Why is GenBank important and What is GenBank format?

Q: What is a database? What types of information are stored within adatabase? Where does the…

A: The complete set of chromosomes present in the organism is known as the genome. Bioinformatics…

Q: Why is genome database and annotation relevant to Genome sequencing?   Are there any examples?

A: Genome: the set of genes. Genome database: it is the collection of all information on the human…

Q: What is central dogma of molecular genetics? How does it work ?

A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…

Q: Which is a limitation of using massively parallel sequencing ?

A: It is a term used to describe the method of high-throughput DNA sequencing to determine the entire…

Q: What are the differences between a DNA library and acDNA library?

A: For the gene cloning method, the DNA is used, which is cut and ligated in the vector. This…

Q: what are the purpose of sequence alignment? define local alignment and global alignment?

A: Alignments are an effective method for comparing similar DNA or protein sequences. DNA molecules are…

Q: What Is a DNA Library?

A: For constructing DNA libraries, the DNA is processed using restriction enzymes. The components of…

Q: What impact does RDT has on genetics and society?

A: Using recombinant DNA technology for the production of genetically modified organisms for commercial…

Q: What is a genomic library?

A: Deoxyribonucleic acid (DNA) is a molecule composed of two polynucleotide chains. It coils around…

Q: What is GenBank used for?

A: The introduction of automated DNA sequencing has created the revolution in biological data…

Q: What are gene microarrays? How are microarrays used?

A: The process of forming a single double-stranded nucleic acid molecule by combining two…

Q: What provides a convenient bridge between the low resolution of a karyotype and the ultra-high…

A: Introduction  Cytology refers to the study of cell such as cell morphology, physiology etc. As we…

Q: What is a cDNA library, and for what purpose can it be used?

A: In genetics, the term cDNA library refers to the library containing the group of cloned copies of…

Q: How to create DNA-sequence alignment ?

A: DNA-Sequence alignment can be defined as the way in which sequences of DNA samples are arranged for…

Q: What are genomic DNA libraries ?

A: Contains DNA fragments representing entire genome of an organism. Created using molecular cloning.…

Q: Why is QTL mapping in human genetic diseases important?

A: Human genetic disease or hereditary disorders is an illness brought about by changes in an…

Q: What is oligonucleotide microarray?

A: An array is an orderly arrangement of samples where matching of known and unknown DNA samples is…

Q: What is the annotation of the genome?

A: A gene is the fundamental unit of heredity, physical and functional. Gens consist of DNA. Some genes…

Q: Define the Single-cell sequencing (SCS) ?

A: Working of Single-cell deoxyribonucleic acid genome sequencing involves analytic one cell,…

Q: What does SDS–PAGE stand for? What is the benefit of doing SDS– PAGE?

A: Electrophoresis is the migration of charged particles under the influence of an electric current.…

Q: What is the difference between RefSeq and GenBank?

A:

Q: What does 'biological sequence database' refer to?

A: Bioinformatics aids in the storage and process of large biological information by the aid of…

Q: What is pharmacogenomics and how might it benefit patient care?

A: Pharmacogenomics is the study of how genes affect a person's response to drugs. This relatively new…

Q: what are similarities and differences between chain-termination and reversible terminator…

A: Gene sequencing  aids in the development of gene therapy, a form of treatment that replaces faulty…

Q: What is the difference between a genomic library and a cDNA library?

A: The genomic library is a set of cells that together contains an organism’s whole genome that is cut…

Q: What is the principle behind to Sanger sequencing?

A: Sanger sequencing is a method of DNA sequencing, which is based on selective incorporation of…

Q: Approximately how many base pairs were identified in the human genome working drafts?

A: The human genome project is a scientific project led by James Watson and Francis Collin, started in…

Q: What would be a medical advantage of having a catalog of SNPs?

A: A single-nucleotide polymorphism is a substitution of a single nucleotide at a unique position in…

Q: What is genomic sequencing and what are the 3 primary ways of annotating a gene?

A: A genome sequence:It is the total nucleotides list that include A, C, G, and T for the DNA genomes…

Q: What is the motive behind Genome Project 10K?

A: The advent of low-cost, high throughput sequencing has ushered in a new age of genome science and…

Q: Explain how substitution matrices can be used to improve the possibility of identifying related…

A: Protein is a macronutrient that is vital for building muscle mass. It is normally found in creature…

Q: How can libraries be used to locate a specific gene of interest?

A: Scientists use genetic engineering methods to create two different types of DNA libraries. These are…

Q: When is low diversity especially problematic in sequencing?

A: In sequencing micro RNA any method which requires use of in house barcodes may results in giving low…

Q: What is a DNA library? Do you think this name is appropriate?

A: In terms of molecular biology, a library can be defined as the collection of DNA fragments that are…

Q: What is an advantage of RNA Seq over microarrays?

A: The process in which the sequencing of total messenger ribonucleic acid (mRNA) is carried out…

Q: What are frame-shift insertion?

A: Mutations are changes that occurs in the deoxyribonucleic acid (DNA) sequence, either due to…

Q: Hi, I would like to know which program is used for the graphical presentation of the results of a…

A: A genome wide linkage association study (GWAS) is an approach used in genetic research to associate…

Q: Which are the limitations of using massively parallel sequencing to sequence a genome?

A: Massive parallel sequencing, also known as next generation sequencing or second generation…

Q: What are the main differences between bottom up/shotgun and top down proteomics strategies?

A: Proteomics studies plays an important role in biomarkers and drug targets. Mass spectrometry (MS) is…

Q: What is the primary disadvantage of Sanger sequencing?

A: Sanger sequencing the target DNA sequence is determined by copying it into the fragments of…

Q: "Whole-Genome Sequencing Is Widely Used for Sequencing and Assembling Entire Genomes". Explain this…

A: Whole genome sequencing It reveals an organism's complete DNA make-up ( allowing us to better…

Q: What is GenBank ?

A: The study of genomes' architecture, functioning, development, sequencing, and modification is the…

Q: What is a genome and what is it composed of? What is thecentral dogma of molecular biology?

A: Genes are the hereditary units that are transmitted from one generation to another generation. The…

Q: What key molecules are essential for Sanger sequencing?

A: DNA sequencing is used to determine the exact arrangement of the nucleotide bases adenine (A),…

Q: What is GenBank in bioinformatics?

A:

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.