Why is genetic engineering such a controversial ethical issue? How would you assess the importance of the Ethical Legal Social Implication (ELSI) Program's impact on the privacy and confidentiality of genetic information, and its implications for medical practice, genetic counseling, and reproductive decision making?
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- Discuss the use of biotechnology and genetic engineering for medical, environmental, legal, and pharmaceutical uses. What are the pros and cons to our society? Why is genetic engineering such a controversial ethical issue? How would you assess the importance of the Ethical Legal Social Implication (ELSI) Program’s impact on the privacy and confidentiality of genetic information, and its implications for medical practice, genetic counseling, and reproductive decision making?write a comprehensive, one-page position paper about your stand on the practice of stem cell therapy and genetic engineering. Consider the following guide questions in establishing your arguments: •Could the widespread use of gene therapy make society less accepting of people who are different? •Will genetic engineering permanently change our society?Do you think it is ethical (morals: right or wrong), safe, and helpful for scientists to continue with genetic engineering? Write a paragraph explaining two reasons to support and two to disagree with the practice of genetic engineering.
- Mary and Marcie. identical twins, go to the same internist who is also a faculty member at a major medical center. At their last visit, they each received a brochure describing a genetics research program recently launched by the hospital and its affiliated university. Researchers were asking for volunteers to fill out a questionnaire and a consent form, donate a blood sample, and have their medical records encoded and transferred to a database. The goal was to enroll 100,000 participants, and the brochure noted that over 10,000 people had already agreed to participate. The blood sample would be used to extract DNA. which would be encoded with the same number as the medical records. This DNA would be used to search for genes associated with conditions such as arthritis, diabetes, and Alzheimer disease. The idea is that researchers interested in studying arthritis would use the medical records to identify which participants have the condition and then use DNA from those individuals to find genetic similarities that are not present in participants who do not have arthritis. The genetic similarities help identify regions of the genome that contain genes associated with arthritis. These regions can then be studied in detail to identify and isolate genes that may be associated with arthritis and other inflammatory disorders. In exchange for enrolling, participants would be informed about any genetic conditions or predispositions to genetic disease they carry and would receive free access to testing. After discussing the brochure. Mary decided to enroll, but Marcie decided she did not want to do so. She said she did not want to know what diseases she may develop or which disease genes she may carry. At their next annual visit. Marys internist told her that because her questionnaire indicated that some relatives had Alzheimer disease, her DNA was used in a study to identify risk genes. He said she had been identified as a carrier of a gene that greatly increased the likelihood that she would develop Alzheimer disease. The physician told her that age was the greatest risk factor, and while it was not 100% certain she would become a victim of Alzheimer disease, the gene she carries is a factor in 2025% of all cases. Mary asked if there was anything she could do about these findings. The internist told her that exercise, controlling blood pressure and cholesterol levels, as well as participating in mentally challenging activities such as reading or playing a musical instrument may all help reduce her chances of developing this disease. Mary then asked if Marcie was going to be told about Marys genetic risk, and the internist said that he would not tell her. For the next few days. Mary was conflicted about the situation. Marcie was an Identical twin, and If Mary carried a gene predisposing her to Alzheimer disease. Marcie must carry the same gene. Marcie did not exercise with Mary, had high blood pressure, and little interest in reading or social activities. Mary did not know whether she should tell Marcie. If you were advising Mary, what would you say? Should she tell Marcie about the risk? Should she not tell her, but instead try to get Marcie to exercise and be more social? Should Mary ask their internist to talk with Marcie about this?As genetic testing becomes widespread, medical records will containthe results of such testing. Who should have access to thisinformation? Should employers, potential employers, or insurancecompanies be allowed to have this information? Would youfavor or oppose having the government establish and maintain acentral database containing the results of individuals’ genomescans?What novel applications or ethical considerations arise from the integration of genomics and personalized medicine?
- Think of a possible safety or ethical issue related to genetic engineering and explain briefly why this is a valid concernexplore the social and ethical issues created by the multiple applications ofmodern genetic research?What are the advantage and disadvantages of genetic engineering. Give at least five each.