Why is the HbS allele (A₂) eventually lost in the first set of simulations, but not in the second set of simulations? Briefly explain by including genotype fitness differences in your response.
Why is the HbS allele (A₂) eventually lost in the first set of simulations, but not in the second set of simulations? Briefly explain by including genotype fitness differences in your response.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
100%
Transcribed Image Text:Population Data
Population: Finite
N = 200
Frequency A₁ Allele
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1-
Frequency A₂ Allele
0
0.9
0.8-
0.7
0.6
0.5-
0.4
0.3-
0.2
0.1
of
0
ro
T
20
Allele Frequency
# of Populations 5
# of Generations 200
freq A₁ 0.5
20
T
40
GO
T
60
40
A₁A₁
0.5
Fitness (w)
1
T
80
A₁ A₂
T
60
0
A₂A2
Change in A₁ Allele Frequency Over Time
T
100
Generations
Migration
120
80
None
140
100
0
Generations
A₁ ==>A₂
T
120
T
160
Mutation
Change in A₂ Allele Frequency
0
A₁ <==A₂
180
T
140
Q+ == #
Inbreeding
T
160
F
(temporarily disabled)
0
Infinite Population
Pop_1
Pop_2
Pop_3
Pop_4
-Pop 5
O Q + + -
T
180
Start gen Stop gen Pop Size
Bottleneck
Info.
Growth Rate
1
Populations
# with A₁ Fixed=0
# with A₁ Lost = 0
Average # of Generations till
Fixation
=N/A
=N/A
(no populations with A₁ fixed)
Average # of Generations till loss
(no populations with A₁ lost)
Infinite Population
Pop_1
Pop_2
Pop_3
Pop_4
Pop_5
Transcribed Image Text:• Set A₁A₁ (HbAA)
• Set A₁A₂ (HbAS)
• Set A₂A₂ (Hbss)
Why is the HbS allele (A₂) eventually lost in the first set of simulations, but
not in the second set of simulations? Briefly explain by including genotype
fitness differences in your response.
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