You are investigating a case of SCID in which you have observed that the diversity of both T- and B- cells (that is, diversity of both the TCRS and BCRS on the cells of this patient) is drastically reduced. List two genes whose mutation could produce this result, and briefly explain what each one's product normally does.

You are investigating a case of SCID in which you have observed that the diversity of both T- and B- cells (that is, diversity of both the TCRS and BCRS on the cells of this patient) is drastically reduced. List two genes whose mutation could produce this result, and briefly explain what each one's product normally does.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section12.4: B Lymphocytes: Antibody-mediated Immunity

Problem 3CYU

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