You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly elected compound from the table below) of aspirin/ paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug.Important: your company wants efficiency, a ynthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that mvolve working with lots of ring deactivating groups) is Br OH
You are working for a drug discovery company. Your team has identified a derivative (you will be given a randomly elected compound from the table below) of aspirin/ paracetamol, has optimal physicochemical properties for biological activity. To conduct preliminary tests on the drug candidate you are required to synthesise the derivative from benzene. Propose a synthetic pathway starting from benzene to the candidate drug.Important: your company wants efficiency, a ynthetic, pathways that provide good yield (major product) and are energy efficient (if possible, avoid pathways that mvolve working with lots of ring deactivating groups) is Br OH
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter18: Functional Derivatives Of Carboxylic Acids
Section: Chapter Questions
Problem 18.42P
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