You have 150 mL of 0.25 M n-propylamine and you shake this in a mixture of 90 mL of water and 50 mL of an organic solvent and let it achieve equilibrium. You removed the water layer and titrated it using 0.30 M HCl, where end point of the titration was achieved at around 42.5 mL. Calculate for the partition coefficient of n-propylamine and describe the affinity of the compound based on the value you obtain.

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter14: Chemical Equilibrium
Section: Chapter Questions
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You have 150 mL of 0.25 M n-propylamine and you shake this in a mixture of 90 mL of water and 50 mL of an organic solvent and let it achieve equilibrium. You removed the water layer and titrated it using 0.30 M HCl, where end point of the titration was achieved at around 42.5 mL. Calculate for the partition coefficient of n-propylamine and describe the affinity of the compound based on the value you obtain.

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