You will be doing Electrophilic Aromatic Substitiution (EAS) in the coming lab (Nitration). You will nitrate different monosubstituted benzene ring, which include Anisole, Aniline, and Acetanilide. Look up the physical properties for all these compounds and the expected product of each reaction. Also, you will using Nitric acid, and sulfuric acid. H3C-0 NO₂ 3=3-28 HNO3 NH₂ H₂SO4 NH₂ 6-6.5.8 + NO₂ HNO₂, H₂SO NH₂ HNO3 CH, or H₂SO4 NO₂ + CH₂ of grot NO₂ NH₂ NO₂ NO₂ "3=-3-23 NO₂ CH₂ NO₂

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Chapter23: Carbonyl Condensation Reactions
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You will be doing Electrophilic Aromatic Substitiution (EAS) in the coming lab (Nitration). You will nitrate
different monosubstituted benzene ring, which include Anisole, Aniline, and Acetanilide. Look up the
physical properties for all these compounds and the expected product of each reaction. Also, you will
using Nitric acid, and sulfuric acid.
H3C-0
H3C-0
H3C-
NO₂
3= 32
HNO3
H₂SO4
NH₂
NH₂
NH₂
NO₂
6-6.5. &
+
NO₂
HNO₂, H₂SO₂
HNO3
H₂SO4
H3C-0
NH₂
NO₂
NO₂
NO₂
CH₂
CH₂
CH₂ or
of Gotzof
H3C-
+
H3C
3
NO₂
NO₂
H3C
CH₂
NO₂
Transcribed Image Text:You will be doing Electrophilic Aromatic Substitiution (EAS) in the coming lab (Nitration). You will nitrate different monosubstituted benzene ring, which include Anisole, Aniline, and Acetanilide. Look up the physical properties for all these compounds and the expected product of each reaction. Also, you will using Nitric acid, and sulfuric acid. H3C-0 H3C-0 H3C- NO₂ 3= 32 HNO3 H₂SO4 NH₂ NH₂ NH₂ NO₂ 6-6.5. & + NO₂ HNO₂, H₂SO₂ HNO3 H₂SO4 H3C-0 NH₂ NO₂ NO₂ NO₂ CH₂ CH₂ CH₂ or of Gotzof H3C- + H3C 3 NO₂ NO₂ H3C CH₂ NO₂
Step 1: Electrophile generation
40
NO
tep 2. Niation (EAC)
ooks
NH₂
NO, →
+ NU₂
NO₂ →
4-000₂H4NO₂ 4₂0 +NO₂
.
-
NACOOKS
colls
FNOG
NHCOCHS
+ 150
+/NO₂ → ²
NH CƯỜN
AA
OCH
-#
NO₂
t
[resonance]
NO₂
->>
Step 1: electrophile generation is the crame
Skp 2 Nitrata
N4₂
Nih
+ NO, →
H
-
4
+
NO₂
19
+ H50₁₂ →
NN₂
#NO₂
NHẠC CH
# NU₂
His
NHCOCK 3
actly
or the position
NO₂₂₂
NHCOCHS
H₂ +150
paty
NO₂
+150-
NH₂
Nc₂
HưOF NHI
NH
+1807
Troy
partin
някост
-NU₂
Willy
-NO₂ + H₂SO₂
ortho
par a
NHCOCHS
meta
NACOCH 3
-NO₂
NHẠCH
-Nu₂
Transcribed Image Text:Step 1: Electrophile generation 40 NO tep 2. Niation (EAC) ooks NH₂ NO, → + NU₂ NO₂ → 4-000₂H4NO₂ 4₂0 +NO₂ . - NACOOKS colls FNOG NHCOCHS + 150 +/NO₂ → ² NH CƯỜN AA OCH -# NO₂ t [resonance] NO₂ ->> Step 1: electrophile generation is the crame Skp 2 Nitrata N4₂ Nih + NO, → H - 4 + NO₂ 19 + H50₁₂ → NN₂ #NO₂ NHẠC CH # NU₂ His NHCOCK 3 actly or the position NO₂₂₂ NHCOCHS H₂ +150 paty NO₂ +150- NH₂ Nc₂ HưOF NHI NH +1807 Troy partin някост -NU₂ Willy -NO₂ + H₂SO₂ ortho par a NHCOCHS meta NACOCH 3 -NO₂ NHẠCH -Nu₂
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