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  • Feasibility Of Designing Partial Agonists Of The Human Muscarinic Receptors

    983 Words  | 4 Pages

    This article presents a study performed to demonstrate the feasibility of designing partial agonists of the human muscarinic M1 receptor that would modulate the receptor in two distinct ways simultaneously. It also explains the signaling behavior of the receptor. The muscarinic M1 receptor was described as the one of five subtypes of the muscarinic G protein-coupled receptors (GPCRs) with the highest expression in the central nervous system. Two downstream effects of activating the M1 receptor were

  • Case Study : New Ob Visit

    1187 Words  | 5 Pages

    Date: 08/22/16 Formal Write-Up #2 CC: New OB HPI: YM is a 24 year old G2P1 who presents for New OB Visit at 28 weeks 6 days. Her concerns are the following: 1. Diarrhea – The patient reports traveling to Hawaii approximately 3 weeks ago. She returned home with loose stools. She had a stool sample that showed positive parasites, and was subsequently started on Metronidazole. She finished that course of antibiotics. After that, she continued to have persistent diarrhea. She was worked up for

  • Symptoms And Diagnosis Of Schizophrenia

    1563 Words  | 7 Pages

    Schizophrenia is one of the most severe psychiatric disorders that affects both male and females, respectively. This illness is characterized by gradual increase in changes of perception, thinking, social activities, speech, feelings, and motivations. Many studies have shown that there is a clear difference in outcome between genders including symptom severity, age-at-onset and functional outcome (as cited in Gogos, Kwek and van den Buuse, 2011, p. 213). For example, schizophrenia occurs on average

  • Organ Bath Experiment

    1602 Words  | 7 Pages

    aorta tissue. The hypothesis is the CRA mechanism will reach max contraction, but higher concentration of agonist is needed to reach max contraction in presence of antagonist, the NCA mechanism will show decrease in max contraction of agonist with presence of antagonist, and physiological antagonism will show relaxation of tissue due to the action of antagonist during presence of agonist. Each agonist

  • Agonist Muscles

    968 Words  | 4 Pages

    Example 1: javelin Preparatory phase Joints involved Articulating bones Action Agonist Muscle Shoulder Humerus & scapula Horizontal hyperextension Posterior deltoids and latissimus dorsi Elbow Humerus & ulna Extension Triceps brachii Throwing contains of two phases, the preparatory phase and the throwing phase. predominantly the majority of actions are rotational in the transverse plane and longitudinal axis and also both joints mainly involved are the elbow, the elbow is a type of joint called

  • Pimavanserin

    1103 Words  | 5 Pages

    classifications of serotonin receptors, as well as drug classes that act upon serotonergic transmission are discussed below. This includes serotonin (5-HT) agonists, antagonists and medications that modulate 5-HT at the presynaptic level, all of which are of significant clinical relevance. Nuplazid (pimavanserin), is a selective serotonin inverse agonist (SSIA). Pimavanserin is a non-dopaminergic atypical antipsychotic drug with primarily selective inverse agonistic and minor selective inverse agonistic

  • Lysergic Acid Diethlyamide Essays

    4283 Words  | 18 Pages

    Lysergic Acid Diethlyamide The psychedelic effects of d-Lysergic Acid Diethylamide-25 (LSD) were discovered by Dr. Albert Hoffman by accident in 1938. In the 1950s and 1960s, LSD was used by psychiatrists for analytic psychotherapy. It was thought that the administration of LSD could aid the patient in releasing repressed material. It was also suggested that psychiatrists themselves might develop more insight into the pathology of a diseased mind through self experimentation. 1,2 During the late

  • Relevance Of Study And Scientific Background

    1677 Words  | 7 Pages

    -helices that run through the membrane with parts both inside of the cell and outside of the cell (1). The widely accepted model for GPCRs work is outlined in Figure 1 of this paper (2) and is essential for understanding the rest of the paper. An agonist binds to 2AR.Then changes occur to 2AR such that a Gs heterotrimer complex can bind to the 2AR better. The Gs

  • A Short Story : A Good Man Is Hard To Find

    1033 Words  | 5 Pages

    The short story “ A Good Man is Hard to Find” is a story that quite frankly left me perplexed the first time I read it. The story is written in a third person perspective that follows the road trip of a grandmother and her son Baileys family, which is comprised of Baileys wife whose name is never mentioned in the story and their three children John Wesley, June Star and a baby that’s name is not mentioned either. The story is set mainly in the family car, with a stop at a local diner and ultimately

  • The Role Of 3, 4-Methylenedioxymethamphetamine In The Scientific Community

    1535 Words  | 7 Pages

    A 5-HT2A receptor antagonist blocked the social effects of MDMA. A 5-HT2C agonist decreased huddling but did not affect social vocalizations, and a 5-HT1A agonist decreased huddling (Pitts et al., 2017). The researchers concluded that MDMA and its enantiomers increase the frequency of affiliative behaviors and vocalizations in a dose-dependent fashion, and the behavioral