Sepsis

‘Sepsis’, a lame man might hear of this word and have no clue or whatsoever of what this is – but in the real world it’s not something to be happy about and has been a major issue in the medical field. Sepsis is a complex condition which doesn’t have a specific definition, diagnosis or treatment but one thing the medical practitioners are specific of is the origin. Sepsis is from a Greek word called “Sepo” which means “decay” idiomatically known as “Blood poisoning” (Steen C., 2009). The medical

Sepsis is one of the leading causes of morbidity and mortality globally, the 10th leading cause of death in the United States and the second leading cause of death in non-cardiac intensive care units [1]. Each year between 400,000 and 500,000 cases of sepsis occur in the United States and the cost of caring for a septic patient is high, resulting in a national economic burden of almost 17 billion dollars per year [1-2]. Sepsis is a serious health concern and a better understanding of the causes and

With sepsis becoming a growing concern with each passing day, we must develop new ways to combat it aggressively. With EMS becoming a more advanced, educated, and integral member of the health care team; there must be an inclusion of them into the early and advanced treatment of sepsis. According to a research team in the Netherlands 3.3 out of every 100 patients encountered by EMS in the United States have severe sepsis diagnoses, compared to only 2.3 per 100 for myocardial infarction and 2.2

On his death certificate they declared his cause to be Sepsis by an unknown origin. Sepsis is defined as a systemic inflammatory response that occurs within the body due infection within the bloodstream. Common sites for infection that cause sepsis include pneumonia, kidney infections, or abdominal infections. The infection can be either bacterial, viral, or fungal. The most common gram positive organisms include staphylococcus aureus and enterococci. Common gram negative organisms include pseudomonas

the time sepsis is caused by “hospital-acquired gram-negative bacilli or gram-positive cocci and often occur in immunocompromised patients and patients with chronic and debilitating diseases” (Maggio). Sepsis “may be associated with the introduction of microbes into the blood stream directly via” invasive hospital instruments (Cuna). B. Pathophysiology – Sepsis is described as a generalized infection that is characterized by the presence of bacteria in the blood. The progression of how sepsis becomes

Thirty to 50 percent of the 400,000 to 500,000 cases of sepsis in the United States each year are fatal, emphasizing the seriousness of this public health concern [2]. Recent research into possible alternative treatment options indicates that patients being treated with statin therapy are less likely to develop sepsis from a serious infection, die from sepsis or develop serious complications due to sepsis; however, the mechanism of action is unknown and therefore is the focus of this study [2, 6

Introduction Sepsis is a potentially life-threatening complication caused by the body’s response to an infection. Our immune system protects us against threats, which include viruses, bacteria and parasites that cause infectious diseases. Our immune system responds by triggering an inflammatory response to bacteria in the blood. However, with sepsis the response is massive and the inflammation that occurs can cause a ripple effect of changes that may lead to damage of multiple organ systems, causing

Introduction Sepsis is a systemic response to infection that leads to severe sepsis and septic shock (Dellinger et al., 2013). Severe sepsis and septic shock are major health concerns, affecting millions of people, and killing one in four (Dellinger et al., 2013). Multisystem organ failure (MOF) is one of the leading causes of death of hospitalized patients with the underlying condition of sepsis (Rittirsch, Redl, & Huber-Lang, 2012). TP is a 57 year old male who presented with severe abdominal

Sepsis in the Older Patient Sepsis is a common condition in critically ill patients. Cases of sepsis rose by an average of 9% per year (Nasa P, 2012) and the number elderly patients being admitted to ICU’s has increased recently. One of the reasons for this trend is that people are living longer. The world’s population of people over the age of sixty has been increasing steadily. It has been projected that over the next twenty years the number of people over the age of eighty will be double and

Sepsis continues to be a significant cause of death and morbidity in the intensive care unit (ICU), with documented mortality rates as high as 50% (Nargis, Ibrahim, & Ahamed, 2014). It is also estimated to be the principal cause of death and illness worldwide (Singer et al., 2016). Moreover, the socioeconomic costs related to sepsis were determined to be more than $20 billion in 2011 in the United States (Balk et al., 2017). Also, there has been a steady increase in the incidences of sepsis as