Colon and rectum are both located in the digestive system. There are two parts of the digestive system. Upper part of the digestive system included stomach and small intestine, in which their job is to digest food for energy. Lower part of the digestive system are called gastrointestinal system, where colon and rectum are located. Its function is to absorb fluid to form solid waste then passes from the body as a stool. Small intestine made up of the most part of the digestive system, it is about 20 feet long. It break down the foods and absorb most of the nutrients. Then it pass to the large intestine which is mainly made up of a muscular tube, colon, and it is about 5 feet long. The colon can be divided into 4 section. Ascending colon, it is the beginning of the colon that included the cecum, where the appendix attaches to the colon. Transverse colon, the second section of the colon. It located in the upper abdomen and from the right to the left. The next section is called descending colon, the lower abdomen and from the left to right. The last section,
There are over 100 types of cancer. One type is called colon cancer, a very common disease in the lower part of the digestive system. Colon cancer is luckily very treatable if caught early, but because it is so common it is the second leading cause of death from cancer. About 140,000 people in the U.S. are diagnosed with colon cancer every year.
The colon also known as the large intestine is an important contributor to the gastrointestinal tract. After food is absorbed in the small intestine it is pushed into the large intestine where the remaining water and vitamin k is absorbed. This is where the absorption water is most important in the G.I tract in keeping excretions regular. Also, the colon is a rich source of microorganisms. Bacteria in the colon assist in the digestion of nutrients we are not able to do because we lack those enzymes that specifically breakdown carbohydrates. To disrupt the balance of the microorganisms or bacteria would in fact cause more harm to your health.
The large intestines are a part of the digestive system (Colorectal cancer, 2015). The large intestines (large bowels) are made up of the colon and the rectum (What is colorectal cancer, 2016). The colon is five feet long muscular tube that makes up the majority of the large bowel (What is colorectal cancer, 2016). After food goes through the small intestines, of the digestive system, the colon absorbs the salt and water from the food that remains and the waste matter (feces) is the byproduct (What is colorectal cancer, 2016). The feces is then expelled from the body through the anus (What is colorectal cancer, 2016).
The signs and symptoms of colon cancer include blood in the stool, weight loss, change in movements in the bowel and fatigue. Most colon cancers are adenocarcinomas because they begin in the cells responsible for making and releasing mucus and other fluids. Colon cancer usually begins as a type of growth known as a polyp which forms in colon or rectum’s inner wall. Some polyps may develop to become cancer after some time. Diagnosing and removing polyps is used to prevent cancer. In the United Kingdom, colon cancer is 3rd most common type of cancer for women and men. However, deaths associated with the cancer have been decreasing after the use of colonoscopies as well as fecal occult blood tests which are used to check for the presence of blood in people’s
The normal cancer-fighting response from the immune system activates white blood cells, also called T cells, which target cancer cells in the area. The cancer-fighting cells also
Squamous cell carcinomas cancer is the most common colon cancer in the United States. It is located within the anal canal and around its walls. This sparks my interest because it is quite odd to me that cancer could occur in the anal canal or outside of it. It really shows how cancer can literally occur anywhere in the body. Even Though it is located in the anal canal, the cause of colorectal cancer is usually due to many other reasons that has nothing to do with the colon itself. These causes are the amount of exercise a person have, any smoking or drinking, even if the person is overweight, or attaining HPV. There are also many causes that can not be changed by your lifestyle, for example if you have the genes to have colorectal cancer or
One of the most common malignancies is colon cancer as it accounts for approximately 1.5 million new cases globally each year (Ferlay et al. 2015). According to the latest research, the frequency of colon cancer has increased suddenly over the past two decades (Shin et al. 2012). According to statistics, colon cancer accounts for about 15% of bodily cancers and is the main reason for mortality in different countries especially the western countries (Johnston 2005). The third most common cancer in the Canada and US is colon cancer. In the United States about 1.5 million new cases of colon cancer were reported each year (Jemal et al. 2008). The chances and a number of years of survival in colon cancer depend on the stage of the tumor.
Inflammatory bowel diseases (IBD) are autoimmune disease whose incidence and prevalence are increasing worldwide. The two major types of IBD are ulcerative colitis (UC), which is limited to the colonic mucosa, and Crohn disease (CD), which can affect any segment of the gastrointestinal tract from the mouth to the anus, involves “skip lesions”, and is transmural. There is a genetic predisposition for IBD, and patients with this condition are more prone to the development of malignancy.
The recognised colon cancer is a lifestyle/genetic disease is ultimately developed from the inner lining of the bowel, followed by growths called polyps which can become invasive cancer if undetected. The disease has become more familiar in Australia and occurs more commonly in people over the age of 50. The symptoms are simple to pinpoint, so it is easy to diagnose the cancer quickly and begin treatment. However, while the condition cannot be prevented it can be easily reduced and strategies are available to stop the cancer in its tracks.
Gastrointestinal cancer (esp. colorectal and esophageal cancer) has been shown to contribute to BM cases. The majority of these types of metastases are due to poor prognosis, which can often be avoided. In colorectal carcinoma, mutations of RAS can be correlated with the increase incidence of BM. Therefore, drugs targeting RAS processing and its upstream effectors (MEK) has
GI (PC and CC) cancer accounts for approximately 30% of the total cancer patient population in the U.S [1;2]. Gemcitabine (Gem), the standard drug for PC, does not improve on the dismal survival rate (median survival increased by only a few weeks) , and FUOX (5-FU+Oxaliplatin) for CC has shown limited clinical utility  especially because of high rate of tumor recurrence. Alternative platinum-based regimens incorporating OX have demonstrated only marginal benefits in PC and CC patients . Emerging evidence suggests that the poor response to the current treatment modalities in GI cancer is linked to aberrations in multiple signaling pathways together with the presence of a small subpopulation of drug-resistant CSCs/CSLCs that have the propensity to promote tumor recurrence, invasion and metastasis . Although genotoxic chemotherapies target the majority of tumor cells, CSCs/CSLCs in the
Colorectal cancer mainly starts at colon or the rectum. They are common in most of the way like features, but they have different treatment. What is the different between colon cancer and rectal cancer? Colon cancer happens first four to five feet of the large intestine and rectal cancer happens in the last few inches of the large intestine where it is connected to anus. (cancercenter.com)
http://kidshealth.org/kid/cancer_center/HTBW/digestive_system.html ( I didnt copy direct quotes, however I had used the idea of the beginning in my research on the digestive system to help the reader better understand the system)