BRCA 2 INFORMATION
BRCA1 and BRCA2 share a lot of similarities. BRCA2 is also a cause for hereditary breast cancer and is also responsible for tumor suppressor proteins. BRCA2 is located on chromosome thirteen. BRCA2 can repair breaks within DNA, such as DSBs and can regulate cytokinesis. Cytokinesis is a process during cell division where the cytoplasm, the fluid inside the cells that is enclosed by the cell membrane, of one parent cells splits into two daughter cells. BRCA2 mutations are more commonly found in people of Jewish and French-Canadian backgrounds.
MUTATIONS THAT LEAD TO BREAST CANCER THAT DON’T INVOLVE BRCA
Mutations in the BRCA1 and BRCA2 genes are the only cause for breast cancer. A mutation in the human epidermal growth
Personally, I feel like BRCA1 may not predict cancer in the future because cancer cells are always evolving. Just because the BRCA1 marker can predict cancer now, it does not mean it can in the future. The makeup of cancer cells may very well change which means the BRCA1 gene mutation would also have to evolve to be able to make those same predictions. This is what makes viruses and cancer such deadly and scary diseases. They are always evolving and retailing against our cures and antibiotics. For example, take vaccines. You purposely inject a very small portion of a virus into your body so your body can learn how to fight out the virus before you get the real thing and become extremely sick. Cancer cells are able to evolve just like the cells
information that until 2014 her only medical condition was Irritable Bowel Syndrome, BRCA1 was identified when an abnormal mammogram came back in 2014. A biopsy was performed due to the calcification being identified on scan, upon biopsy it was identified as stage 1 breast cancer at age of 61. Daughter “K” has no know medical conditions was identified with BRCA1 gene in 2015.
Breast cancer is an uncontrollable division of cells within the breast tissue that affects about 12% of women in their lifetime. Cancer can be caused by sporadic mutations influenced by environment or by genetic disposition. Several genes play a role in cell division: Oncogenes are responsible for directing mitosis, and tumor suppression genes prevent the expression of genes involved in cell division. Mutations that occur in either gene can lead to carcinogenic tumor growth and immortal cell lines.
BRCA 1 can help predict cancer, as it is a mutation in the cell layers. It is a human tumor suppressor gene, which is found in every human. It acts as a protector against furthering steps of cancer, and if it mutates or changes, it will lead to cancer. People can have their BRCA genes tested, and see if they have the precursor to cancer. According to a study done by the National Cancer Institute, if you have an abnormal BRCA1 gene, there is a 60% chance of it evolving to cancer over that person’s lifetime. Restating the definition of Sociological Imagination, it means the ability to connect basic aspects to more impersonal historic forces. Using your sociological imagination, history has shown that most people who develop breast
BRCA1 and 2 are tumor suppressor genes. Both BRCA proteins are used in cellular processes such as DNA repair, regulation of transcription, and maintenance of the genome. Some genes they regulate are vital to cell growth, repair, and death.
This type of breast cancer begins in the milk ducts of the breast. At first, there are normal cells, but then a mutation occurs. Some kind of carcinogen damages and changes a couple of genes. The mutated genes associated with breast cancer are Genes BrCA1 and BrCA2. The
and it is the most common form of cancer identify a disease or its cause after skin cancer among women. Although both men and women can develop this type of cancer, it affects mostly women. Like any other type of cancer breast cancer happens when there are changes in the cells of the breast making them different from what's usually expected and changing quickly to form a lump in the body. Today, doctors have found that only five to ten percent of breast cancer cases are caused by something valuable you get when older relatives die. When breast cancer is caused by something valuable you get when older relatives die is due to a tiny chemical assembly instruction inside of living things change that is passed through generations in a family. There is some received changed in a bad way tiny chemical assembly instructions inside of living things that have been identified that make a person easily able to be harmed or influenced by a higher risk of breast cancer. Among all this different types of born-in tiny chemical assembly instructions inside of living things the most common one is BRCA1 and BRCA2. Both of these tiny chemical assembly instructions inside of living things not only raise the risk of breast cancer but ovarian cancer also. Among different racial groups, White woman are at higher risk for breast cancer. The number of times something happens for this group of 132.5, however although white
An example of this are the BRCA1 and BRCA2 mutations. This genes are relate to hereditary breast and ovarian cancer. Based on the results from a 2007 study, BRCA1 is more than dangerous that BRCA2 because more patients were diagnose and more patients died. The risk of a women dying of cancer if she carries a mutated BRCA 1 gene is very high. There's an 18% chance that a women carrying this gene will die if diagnosed with cancer. Based on the chart 16 out 89 patients died.
BRCA1 and BRCA2 mutations and breast cancer seem to be distributed among a variety of populations.
It was Monday March 17th, 2014 when I received a phone call from my grandma asking me to come visit her. That day is the day when I received the news that my grandma has been diagnosed with invasive lobular carcinoma breast cancer. My grandma and I are very close. Her diagnosis is what persuaded me to write my I- search paper on this specific breast cancer. One topic I am really focusing on when I write my paper is the genetic factors because its important to my family and I. Even though I began to research about the cancer when my grandma was diagnosed, there are still a lot of things I don’t know about and I’m interested to learn about within creating this paper. In this paper I will share with you the importance of invasive lobular
Such findings, all of which relate to hormone-based life events, suggest that breast cancer is somehow affected by prolonged exposure to female sex hormones, such as estrogen. Women with a history of breast cancer in the family are also at greater risk. About five percent of all breast cancers have been attributed to a mutated, or structurally altered, gene known as BRCA1. Mutations in a second gene, BRCA2, contribute significantly to the development of breast cancer in Jewish women. Alcohol, high levels of fat in the diet, and not exercising regularly have also been linked to increased risk for breast cancer (Garber).
Breast cancer, a very painful disease emotionally and physically for women, can also be detected with genetic testing. The majority of cases of breast cancer are not the result of known inherited mutations, but rather from two breast cancer susceptibility genes: BRCA1 and BRCA2. Although the two genes are similar, BRCA1 mutations lead to estrogen receptor negative
We have all seen the pink ribbons. They have become a national, if not international symbol for breast cancer support and awareness. Breast cancer knows neither racial boundaries nor age restrictions. Females of all ages and ethnicities can develop breast cancer and it is the leading most common cancer among women. Calling attention to this often fatal disease is important by supporting its victims, families and friends of victims, as well as raising funds for breast cancer research. Though males are not immune from developing a breast cancer, for the purposes of this paper, this paper will be limited to information relating breast cancer in females.
This is why BRCA-positive people have a higher risk for cancers. It also explains why they get them earlier in life. They were born already having one mutated BRCA allele ready to fuel cancer cells.
This paper will inform you of Breast Cancer. It is the most common form of cancer in women today but thanks to medical advances it is no longer the number one killer of women.