These side effects are more common, although your experience may be different – the range of discomfort or pain varies, depending on your response to the medicine and your current health. Talk with your doctor or health teams – they can help you get through this phase of treatment.
Side effects are part of the treatment and individuals’ response differently – your health care team can offer recommendations to reduce the effects. Be sure to keep them updated on the level of pain – they can’t help if they don’t know. If you have questions about your response and treatments – ask your doctor.
Some side effects will need medical attention, although they are not an emergency. Keep in contact with your doctor to help monitor the effects of
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Do not change the settings and if the alarm goes off – call the doctor nurse.
The first and second cycle of treatments completed under full supervision for observation of responses. Future cycle schedules will change if treatments are interrupted for any reason. After the second cycle, your doctor may adjust the dose of medicine and increase the treatment cycles contingent on the response to bliatumomab. Talk with your doctor to fully understand what’s involved with treatment, the duration and the adjustment of dosage.
Interactions
In all cases of treatment, there is an interactive between medicines – for the most part your doctor has the information of drugs reacting with bliatumomab. When this is a known fact, your doctor may change the dose, frequency or suggest an alternative as a precaution before starting treatment.
This is also the reason, it’s important to share your medical history and current health routines with your doctor. Over-the-counter medication may contain ingredients that will interact with bliatumomab.
Here’s a list of medications that are known to interact with this drug. There may be others not listed. If you have any questions, ask your
Adverse reactions to drugs are common and almost any drug can cause an adverse reaction.
Some side effects of these drugs are nausea, vomiting, diarrhea, weakness, and/or dizziness. If the side effects continue after the first 24 hours, medical attention is required because there can be serious medical problems. Bleeding and severe cramps are expected during the process. Bleeding and spotting may last for more than the next 30 days. Sometimes, the bleeding has needed to be stopped by surgery. Other serious side
You don 't come cross anaphylactic shock often, but you still have to be aware. Other severe adverse reactions that could include a fever and skin blistering; these usually occur within an hour of the medications being administered. Sometimes adverse reactions can develop over a few weeks, they may cause damage to the kidneys or liver. If adverse reactions are not treated they could be fatal. When individuals experience adverse reactions to medicines my workplace policy is to inform the GP and explaining in detail the adverse reactions, the staff member will then inform the individual/ team. GP advise and guidance will then determine if the medication is to be stopped. If the reactions are so serious then an ambulance should be called my responsibility is that I have duty to continue to observe the individual and monitor their vitals, speaking to them and looking at any changes, so as to ensure that the individual is not deteriorating. All adverse reactions and following advice given, must be recorded in full in the individual’s clinical note and referenced in their daily report also MAR’s chart. 4.
In most cases the reactions are mild and if they do occur then first-hand you should consult the medicine box/bottle/DOMAR where it will state any possible side effects on the leaflet or possibly on the main label ir you see on some pain medication ‘’Caution-May make sleepy do not operate heavy machinery’’ etc.
Now, although this pill does seem to be a good thing all drugs come along with a possible negative side effect that may vary from person to person. Students were questioned about their personal uses and what side effects they experienced if they did any and the reports are as followed:
Some of the immediate physical complaints include constantly feeling cold, bloodshot eyes with dark circles, finger calluses, dizziness, weakness, lackluster hair, moodiness, insomnia, no menstruation, swollen glands, weight loss, sore throat, or dry skin. Some of the long-term effects include extreme weight loss, gastrointestinal pain, diarrhea and/or constipation, malnutrition, loss of tooth enamel,
Are there any contraindications for this drug? Hypersensitivity, cross-sensitivity with other NSAID’s such as aspirin, history of allergic reactions, asthma, advanced renal disease, hepatic dysfunctions, perioperative pain.
The health issues listed here are just a glance at what this drug can do to one’s health.
Melinda, I also have the same concern when it comes to side effects and furthermore allergies. This issue can definetely be drawback as it can contribute to non-complience and perhaps even life threathening related to allergies. I think it would be difficult to determine which drug could be the trigger for such reactions. If I was to be the health care provider prescribing this pill I would take into consideration, if the patient had taken any of this drugs separatly prior, to make an assessment if weather it would be a good candidate for the polypill.
Relevant interactions: Diuretics - hypokalemia, predisposing patient to digitalis toxicity. Antacids - decreased absorption of oral digoxin.
Adverse reactions to this medication are migraine, speech disorders, rhinitis, sinusitis, hyperglycemia, elevated liver function, elevated serum creatinine level, pancytopenia, bronchitis, dyspnea, toxic epidermal necrolysis, anaphylaxis, elevated creatine kinase, generalized pain, and infection. Nursing considerations with this medication is to have the patient swallow the whole tablet and not to chew. Watch for aspiration while watching the patient take the medication. Educate the patient about the medication and inform them to notify a physician if bleeding
Chemotherapy is given in cycles a treatment period followed by a recovery period, then another treatment period and so on. The drug enters the blood stream and destroys leukemia cells throughout the body. However, they cannot reach the brain and spinal cord, because of a protective network of blood vessels that keep foreign substances from entering the central nervous system. In certain cases doctors need to inject the drug directly into the fluid that surrounds the brain and spinal cord. (Health a to z, 20)
As a result of the clinical trials and other studies, the FDA requires that the patient should be given a copy of the medication guide and patient agreement. These require that each patient understand and sign a form that has information on what side effects can and probably will occur, in addition to other pertinent information regarding the drug. The side effects that most patients can expect to occur are vaginal bleeding and uterine cramping. Most bleeding or spotting lasts for an average of 9 to 16 days. Other commonly reported side effects include nausea, vomiting, and diarrhea. Rarely occurring side effects include pelvic pain, fainting, headache, dizziness, and asthenia (FDA, 2000).
bacterial urinary tract infection, which is the most common side effect, may occur.21 Other patients
Other side effects include cloudy urine, proteinuria, irregular heartbeats, and chest pain. Angioedema involving the extremities, face, lips, mucous membranes, tongue, glottis or larynx has been seen in patients treated with ACE inhibitors, including captopril (Capoten, 2014). If these effects happen nurses should be ready to administer epinephrine to reduce swelling. Other adverse effect according to Karch (2014) include, “CV: Tachycardia, angina pectoris, heart failure, MI, Raynouds syndrome, hypotension in salt-or volume depleted patients.”