Celiac Disease

When the gluten reaches the small intestine, it activates the immune system to attack the intestine lining. Destroying the finger like projections called Villi which are involved in the absorption of the nutrients.

Celiacs disease (gluten-sensitive enteropathy) is a condition where in some people, gluten cannot be digested and causes an immune response. Gluten is a protein found in wheat, barley, oats, and rye. In some people who take in and ingest gluten, an enzyme named transglutaminase transforms the gluten into a chemical that triggers an immune reaction, causing irritation and inflammation of the lining of the small intestine (Wedro, 2016). The microvilli that make up the inside surface of the intestine are destroyed, causing nutirents to pass without being, like our body needs from our diet. This can cause damage to other organs in the body due to malabsorption. (Wedro, 2016) Organs that depends the most on nutrients to function properly consist of the liver, bones and the brain. This is crucial especially in children because malnutrition can lead to abnormal growth and development. (Wedro, 2016) Celiacs disease can also be known by Coeliac Disease. Roughly 8,000 years after its first appearence, celiacs disease was identified and named. A Greek physician named Aretaeus of Cappadocia who lived in the first century AD, wrote about “The Coeliac Affection.” Also, he called it “koiliakos” after the Greek word “koelia” meaning abdomen. (Guandalini, 2007) Another 17 centuries passed, and in the early 19th century Dr. Mathew Baillie, presumably unaware of Aretaeus, published his observations on a chronic diarrheal disorder regarding adults, causing malnutrition and characterized by a

Celiac disease, which is also called coeliac disease, is a genetic autoimmune disease that injures the small intestine. Gluten is a protein that is in some wheat, barley, and rye. It is also a new fad diet and being gluten intolerant is something a majority of the population may claim. However, for those who really have celiac disease it is more serious. In fact, "Despite popular belief, celiac disease is a serious genetic autoimmune disease, not the latest fad diet", according to the organization Beyond Celiac(What is Celiac Disease, 2016). This article also gives a great explanation about what gluten does to the small intestine on a cellular level. The definition on the webpage goes on to include "When people with celiac disease eat foods containing gluten, their immune system responds by damaging the finger-like villi of the small intestine. When the villi become damaged, the body is unable to absorb nutrients into the bloodstream, which can lead to malnourishment" (What is Celiac Disease, 2016). It also mentions that when celiac is left untreated, other autoimmune diseases are very common such as thyroid disease, osteoporosis and other cancers. Migraines, diabetes, and infertility are a few more illnesses that go hand in hand with celiac. (What is Celiac Disease, 2016).

S lactose intolerance, mouth ulcers, and IBS (irritable bowel syndrome). Damage to your small intestine may cause you to experience abdominal pain and diarrhea after eating lactose-containing dairy products, even though they don't contain gluten ("Celiac Disease," n.d.). Mouth ulcers become apparent as a late sign and symptom of celiac disease. Celiac disease has symptoms similar to other digestive disorders, such as irritable bowel syndrome, gastric ulcers, Crohn's disease, parasite infections and anemia ("Celiac Disease,"

“In this disorder the gastrointestinal tract is the major site of harm and it is also classified as an autoimmune disease. An autoimmune disease is a disease where the body instead of helping cure itself actually attacks itself.” The immune system begins trying to kill parts of the body that are healthy and functioning correctly. Also, more times than not the parts of the body it starts trying to kill need to be alive in order to live. “What happens in Celiac disease is the immune system treats gluten as a foreign object and inflames the villi in the small intestine in order to protect the body from what the immune system sees as an invader. This causes a problem because the villi in the small intestine enable the body to digest and absorb food. When they are inflamed and eventually flattened, they can no longer perform. This leads to malnourishment or a lack in nutrition” (Green). The villi can no longer do its job of absorbing nutrients into the body so no matter how many different kinds of food and how much of it they eat, the person will remain malnourished until they cut gluten out of their diet and the villi become healthy again (Langwith). Depending on each individual that has Celiac disease this effect can either progress rapidly or gradually (Green).

What is celiac? Celiac Disease is an autoimmune disorder that results in damage to the lining of the small intestine. When you have celiac disease your immune system does not protect it from foreign invaders. When you eat things that contain gluten, their immune systems form antibodies to gluten which then attacks the intestinal lining. when your body starts to attack itself it causes inflammation in the intestines and damages the villi.

When a person with celiac disease eats a food contains gluten, an immunologic response occurs and the small intestines are damaged due to the response, which hurts proper absorption of nutrients. If the disease is untreated it may lead to iron deficiency anemia, and osteoporosis, as well as increase the risk of lymphoma, due to this impaired absorption. If someone with coeliac disease consumes gluten can include: bloating, abdominal pain, diarrhea, weight loss, impaired growth rate, weakness, tiredness, and malnutrition. Some people are reported to vomit after gluten consumption (Celiac Disease, n.d. ; Celiac Disease Facts, n.d. ; Celiac disease – sprue. n.d.; Coeliac Disease – NHS, April 2010.).

When a person eats gluten, which is a protein that causes an attack on the villi’s of the small intestines, which are described as small finger-like structures and damages the villi’s in return it’s very difficult for a person to absorb any nutrients. That is why there is many long term affects in a person’s health. Where they either have Iron deficiency anemia, or early osteoporosis, vitamin and mineral deficiencies and many more health conditions. There are many symptoms to Celiac disease, and that is why it’s difficult to diagnose a person. Some people who have Celiac disease have little or no symptoms. There are several treatments for Celiac disease which are Gluten-free diet, vitamins and dietary supplements and bone health. Of course, the patient can treat Celiac disease with choosing to not eat gluten products such as cereals that contain wheats and processed foods. Eating foods like fruits and vegetables would be convenient for the person who has Celiac

Celiac Disease (CD) is a digestive disease triggered and continued by the ingestion of gluten in the diet. Individuals with celiac disease have an irreversible intolerance to gluten. Celiac disease is also known as celiac sprue, nontropical sprue, and gluten-sensitive enteropathy. CD is considered an autoimmune disease. It is activated by eating gluten-containing foods. People who are genetically susceptible can experience varying degrees of lesions in the small bowel mucosa. The lesions can range from “mild intraepithelial lymphocytosis to severe mononuclear infiltration which can result in total villous atrophy”. (García-Manzanares,).

CD is an autoimmune disorder that affects the small intestine. The small intestine is largely responsible for breaking down macromolecule, like carbs and fats, and absorbing nutrients. After gluten is ingested the body begins producing autoantibodies that to begin to attack the patients own cells. This leads to an inflammatory reaction in the small intestine. Long-term inflammation then leads to the shortening of villi lining the intestine. Villi are important for the absorption of nutrients. (See figure 1).

Someone with gluten sensitivity may experience the following gluten sensitivity symptoms- they may fail to gain weight or may lose weight mostly due to the ability to absorb carbohydrates and fats. They may also experience loose bowel movement with excretions of pale and malodorous stool. Another common predicament caused is the development of casein

DEFINITION: Celiac Disease (Sprue) is a disorder of the small intestine characterized by permanent inability to tolerate dietary gluten (a protein found in wheat and other grain products). When a person with celiac disease eats foods containing gluten, an immune reaction occurs in the small intestine, resulting in damage to the surface of the small intestine and an inability to absorb certain nutrients from food. This condition is manifested by diarrhea, malnutrition, and a bleeding tendency. No treatment can cure celiac disease. However, you can effectively manage celiac disease through changing your diet.

Gluten sensitivity is a condition in which your body does not react well to foods that contain the protein gluten, which is found in wheat, barley and rye. It differs from the more serious celiac disease, which is an autoimmune disorder that destroys the lining of the intestines, resulting in poor absorption of essential vitamins and minerals. Unchecked celiac disease, in fact, can lead to cancer. However, gluten sensitivity does not lead to these complications, although it can cause you great gastrointestinal discomfort. According to the WebMd website, you may present with bloating and pain, but you may also experience symptoms outside the gastrointestinal tract, such as fatigue. If you have any symptoms that suggest that something is amiss in your intestinal tract, you should see a doctor--the sooner, the better.

Celiac disease is a genetic, immune disease that targets the small intestine and is triggered by the consumption of gluten. Gluten is a protein primarily found in foods such as wheat, rye, and barley. Additionally, gluten has been included into man-made products such as medicines, vitamins and supplements, lip balm, and the glue on the backs of stamps and envelopes. When eaten, these gluten products affect the immune system’s response leading to the deterioration of the small intestine (U.S. National Library of Medicine, 2015).

While coeliac disease is often asymptomatic and underdiagnosed, the villous atrophy may cause severe malnutrition leading to abdominal pain, changes in bowel movements, weight loss, anaemia, fatigue, reduced growth, osteoporosis, infertility, and neurological problems and may also cause gastrointestinal cancers (Alaedini & Green, 2005). Further, coeliac disease may also manifest itself in dermatitis herpeiformis, a severe skin rash. Coeliac disease is usually diagnosed through endoscopy of the duodenum or intestinal biopsy while the patient is on a gluten containing diet, or through serological or genetic testing (Alaedini & Green, 2005). The only therapeutic option for affected individuals is a life-long gluten free diet and in over 95% of case this leads to an abatement of symptoms within weeks, but regeneration of the duodenum may take more than 12 months (Lee, et al., 2003). The suggested maximum permissible daily intake of gluten ranges between 10mg and 100mg (Hischenhuber, et al., 2006), and a recommendation of below 50mg per day has been confirmed in a