Essay Characteristics of Non-coding RNA

(ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information

study it was reported that miR-221 and miR-222 had antiangiogenic characteristics in endothelial cells. This study came up

What is a gene? The definition of what constitutes a gene has developed throughout history in light of new research and information. In generic terms, a gene is part of a living organism having influence on observable and non-observable characteristics by transfer of genetic information from parent to offspring. The structure of a gene is widely accepted as a sequence of nucleotides consisting of four bases Adenine, Cytosine, Thymine and Guanine. Three bases together determine an amino acid and

(ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information

(ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information

complexity is heavily increased, without any significant change in the number of protein coding genes whereas non-coding portion of the genome has substantially undergone change. It is now well accepted fact that on increasing evolutionary levels, majority of the genome gives rise to non-coding RNAs (ncRNAs) that led to the increased biological complexity. By halting the central dogma – the flow of information from DNA to RNA to protein, ncRNAs have gained central attention. Recent advancement in the next

diagnosis, therapy, and prognosis. This technology enabled researchers to investigate all human genome transcripts, including non-coding versions. Recent investigations have revealed the association of non-coding RNAs (ncRNAs), including miRNAs and lncRNAs, with cancer pathogenesis, prognosis, survival rate and uses of these ncRNAs as cancer biomarker[22-25]. Long non-coding RNA (lncRNA) genes have been defiened

Department, Texas A&M University Kingsville December 5, 2016 MicroRNA-mediated Gene Regulation Introduction MicroRNAs are short regulatory RNAs that modulate gene expression and are expressed in many diseases, including cancer. Studies have shown that microRNAs inhibit the translation and facilitate degradation of their targeted messenger RNAs which makes them a great candidate for the use in cancer therapy (Shahab, 2011, p. 1). Many researchers and scientists are especially finding ways

Abstract Despite the importance of RNA-protein interactions in essential biological processes, there is still only a small number of RNA-protein complexes with high resolution three dimensional structures compared to other biomolecules. In this study, we investigate RNA nucleotide base-amino acid residue interactions by counting contacts in the helical and backbone regions. Contact frequency data from non-redundant RNA-protein complexes is used to estimate relative potential energy of interactions

diagnosis, therapy, and prognosis. This technology enabled researchers to investigate all human genome transcripts, including non-coding versions. Recent investigations have revealed the association of non-coding RNAs (ncRNAs), including miRNAs and lncRNAs, with cancer pathogenesis, prognosis, survival rate and uses of these ncRNAs as cancer biomarker [21-24]. Long non-coding RNA (lncRNA) genes have been defined as an important population of ncRNAs which have key roles in normal development, including