CJD is a serious neurodegenerative disorder, a rare form of rapidly progressive dementia, with a 100% fatality within one to two years of onset. CJD belongs to a family of human and animal diseases known as the transmissible spongiform encephalopathies (TSEs). It is believed to be caused by an abnormal isoform of a cellular glycoprotein known as the prion protein that becomes toxic in an abnormal form (CDC) although Dr. Campellone suggest other proteins may play a role in this disease as well. Although, it is so rare that only between one to every one million people worldwide are diagnosed. The three types of CJD are sporadic, familial, and acquired. First, there is sporadic this is the most common of the three, it occurs for unknown …show more content…
This confusion is due to the similarities of several other forms of dementia that can closely mimic CJD, many tests are ran for process of elimination since CJD is very difficult to diagnose. The symptoms of CJD are very similar to those of dementia, it’s a mental deterioration disease. Symptoms include but are not limited to issues with muscle coordination, personality changes, impaired judgement, thinking, and vision. Some individuals often develop involuntary muscle jerks called myoclonus, and many patients went blind. Pneumonia is also a huge issue that patients with CJD deal with resulting in death from infection. (CDC, Campellone, And Tidy C. D.) Throughout the many test with acyclovir, amantidine, antibiotics, antiviral agents, interferon and steroids to name a few none has shown consistent benefits therefore there are still no known cures for CJD (UCSF). Although Dr. Campellone believes there is hope in tetracycline and/or vaccinations to come soon. For the time being the only treatment available are prescribed to make the patient as comfortable as possible, drugs like clonazepam and sodium valproate may help relieve myoclonus or the irregular, jerking movements. Universities world wide are looking in all directions for help, like “Researchers at the UCSF Memory and Aging
5. What is the prevalence and prognosis of this condition? Is it an inheritable (genetic) condition/disease? (1 point)
Evaluate the extent to which electronic communication enhances or detracts from the quality of interpersonal communication compared to face-to-face communication. Your analysis must engage with three elements of interpersonal communication (for example, eye contact or gestures) and discuss how each is affected by one particular electronic channel of communication. Your essay should be grounded in communication theory from appropriate academic sources.
Proteinaceous Infectious Particles, commonly known as Prions, are extremely rare misfolds of the protein PrPc, which cause fatally neurodegenerative diseases, and are theorized to be infectious only by the protein itself (U.S National Library of Medicine, 1998). This “protein-only theory” is still heavily debated today, as some scientists deny the theory, and there isn’t a significant amount of evidence on each side to qualify the theory or disprove it (Soto, C. 2011). The base “Prion” protein is encoded in the gene PRNP, while being non-infectious. Prions are most commonly found in human prion diseases, but they can also be in other animals in the form of Mad Cow Disease and Chronic Wasting Disease, classified as Bovine Spongiform Encephalopathies
This song has a remorseful and gloomy mood incorporated in it. Early in the song J. Cole depicts himself as selfish and trying to keep to himself. “I like to write alone, Be in my zone,” here J. Cole is explicitly telling us that he would rather do what he does, which is making music, alone. “Until they snatched it from my mama And foreclosed her on the loan I'm so sorry that I left you there to deal with that alone I was up in New York City chasin' panties, gettin' dome Had no clue what you was goin' through,” J. Cole explains to us how he was blinded by sex, money, and fame. He tells us that he was too busy getting panties to care about his mother having her home for closed. Not only was it her home, but the only place he called home throughout
Doctors administer a variety of strategies to diagnose dementia (National Institute of Neurological Disorders and Stroke). It is extremely important that all treatable conditions first be ruled out, such as depression and Vitamin B12 deficiency, which can cause the same type of symptoms as dementia (National Institute of Neurological Disorders and Stroke). Timely and accurate diagnosis of dementia is extremely important for both the patient and their families because it allows early treatment of symptoms (National Institute of Neurological Disorders and Stroke). A variety of tests are used to aid in the diagnosis process, such as neurological evaluations, in which doctors look specifically at patients’ balance, sensory responses, reflexes, and various other functions (National
Creutzfeldt-Jakob disease is a degenerative brain disorder that leads to dementia and ultimately death. Symptoms of Creutzfeldt-Jakob disease (CJD) sometimes resemble those of other dementia-like brain disorders, such as Alzheimer's, but Creutzfeldt-Jakob disease usually progresses much more rapidly.
A possible disadvantage is that If the mentor-mentee relationship is forced, such as when a supervisor assigns an experienced employee to tutor a new hire, it is possible that the two may not hit it off, or that the mentor may feel he doesn't have the time to fulfill the role while still carrying out
While growing up my mother worked at a child development center educating children ages 3-5. I enjoyed watching her interacting with the children. So I decided to try to teach a few of the students like she did and I did very well. This is when I knew I wanted to be a teacher. I worked at Jefferson Place Learning Center for almost 5 years. There I decided there to obtain my CDA to groom my skills as an educator but I was not able to complete this. In 2011, I decided it was time for a change and I decided to leave Jefferson place and moved to KinderCare Learning Center. I really enjoyed working for KinderCare but due to transportation I had quit and I started to work Wal Mart. My heart was heavy because I knew that working for was not something
Humans have to deal with many different diseases and the ones most disliked are the ones with no cures. Like cancer, transmissible spongiform encephalopathies have no cure, but they are more rare. These diseases are prion diseases which cause the brain to deteriorate. Prions are proteins that sometimes behave like viruses, which mean that they should have some form of nucleic acid, but since they don’t, they cause abnormalities. The nervous system contains many normal prions, but when an abnormal prion comes along, it transforms all the normal prions into abnormal ones. Bovine spongiform encephalopathy is found in cattle, but it can be transmitted to humans.
CTE, or Chronic traumatic Encephalopathy, is an incurable progressive degenerative disease that will gradually deteriorates the brain causing the brain to lose mass. CTE is caused by repeated head concussions and by traumatic brain injuries. Brain trauma injuries can lead to a buildup of tau, a protein that slows kills brain cells. CTE is found commonly found in athletes and members of the military. The only way to diagnose someone with CTE is after death through an examination of the brain. CTE can cause symptoms of confusion, mood changes such as aggression and depression, memory loss, anxiety, suicidality, and impaired judgment. CTE is often mistaken for Alzheimer's or Parkinson's due to the fact that both diseases share symptoms with CTE. However Alzheimer's is a progressive disease that slowly destroys memory and important mental functions. Alzheimer's is an incurable progressive degenerative disease that cause gradual brain cells death. Alzheimer's can cause one to experience memory loss, a mental decline, confusion, trouble concentrating, behavioral changes such as aggression, moods such as anger, and depression. Also mistaken for is Parkinson's disease. Parkinson's is a disease that is caused by the deterioration of neurons in the area of the brain called substantia nigra. Without this your body cannot create dopamine. A person with Alzheimer's would experience tremors, muscle stiffness, fatigue and memory
In bovine spongiform encephalopathy (BSE), the disease is caused by the misfolding of proteins that cause proteins and peptides to develop a fibrillary structure. The PrPc is a correctly folded prion and the misfolded form is called PrPSc. BSE occurs when the normal PrPc come into contact with the toxic PrPSc and the normal prion takes on the shape of the PrPSc. The normal chaperones are unable to convert the PrPSc back to the normal form. The PrPSc now takes on the role of chaperone and the conversion of PrPc prions continue over and over. PrPSc, now being hydrophobic avoids the water of the inner cell and begin to accumulate and form plaques along the neuronal cell membranes. The aggregation of the prions on the cell membrane eventually lead to cell death which produces the sponge-like appearance in the brain of cattle infected with BSE (Thompson, 2014).
STAGE 6: Center on universal ethical principles- the person who has reached this stage bases moral judgment in the higher law of truth, justice, and morality.
The following major crime offender characteristics, age, sex, race, and social class, can greatly influence criminals in their own different ways. However, the most the characteristic that can have a bigger impact in some cases is social class. Out of the four characteristics listed, this is the only one that can be changed. The age, sex or race of a person cannot be changed while social class is in fact changeable. A person can change either legally or illegally their social class. If a person is raised in poverty or the lower class of society, regardless of of their sex or race, they desire to have nicer things and live a better life. Living in the lower class society is a motive in itself to have more
* Role models – be able to coach and mentor managers and trainers within the warehouse, People value my input and seek my ideas and suggestions when key decisions need to be made regarding not only Learning and Development but other operational decisions.
Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases that are thought to be caused by the misfolding of prion proteins. Prions are able to replicate in the absence of nucleic acids. TSEs include: scrapie, bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, kuru, Gerstmann-Straussler-Scheinker disease, and Fatal Familial Insomnia. They can affect many different animals, including humans. Currently, there are no ways to diagnose, treat, or cure TSEs, as much more research is needed before these diseases are completely understood.