Angina is considered a pressure or squeezing pain that occurs in your chest area. This is usually due to your heart muscle not getting the blood it needs to the heart. The pain could also happen in your shoulders, arms, jaw, neck, and back.
Stable – Usually happens with physical exertion, but will get better when the person relaxes or rest. The reason for this is that the persons’ coronary arteries are severely narrowed because of plague. When a person is sedate, then the demand for blood is low so that they do not feel any symptoms. When they exert themselves with exercise or do strenuous work then the heart works harder and needs more blood and oxygen, but it cannot get it due to the narrow arteries.
Unstable – This usually is when a person has physical signs of a heart attack and means that one could happen soon. A person that experiences the signs of a heart attack should seek immediate medical help. This conditions is usually brought on by a blood clot that partially or fully block a coronary artery.
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A person may or may not have heart disease. When the spasm happens, it tightens the walls of the arteries, which narrow the artery and that stops or slows the flow of the blood to the heart.
Explain the mechanism of action of the classes of anti-angina drugs (i.e. how do they work?)
Anti-angina drugs are used to help manage angina by way of improving the function of the person myocardium, helping reduce the demand on the heart, or both. The two most popular anti-angina drugs would be organic nitrates and calcium
Another word used to describe a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. A heart attack is the death of a part of the heart caused by the loss of blood supply. The blood supply is usually gone due to a coronary artery being blocked by a blood clot. When a part of a heart artery breaks a blood clot forms around the piece. This blood clot can block the blood flow through the heart muscle. When the heart muscle needs oxygen it is called ischemia. When damage of a part of the heart muscle happens it’s called a heart attack. During a heart attack damage occurs depending on the size of the area blocked by the blood clot as well as the time between the actual heart attack and the treatment. Even though the heart may be hurt, the rest of the organs work with no problems. However, it will not pump as much blood as it used to in order to supply the same amount of blood to all of the parts of the body.
many different medicines are used to treat coronary heart disease. Usually they aim to reduce blood pressure or widen your arteries. For example antiplatelet are a type of medicine that can help reducing the risk of a heart attack by thinning your blood and preventing it from clotting. However there are also side effects after taking the medication like dizziness, diarrioah, nose bleeds and abdominal pain.
Angiotension II receptor blockers-decrease chemicals that narrow blood vessels allowing blood to flow easily and decreases salt and fluid build-up. Antiarrhythmic-treat abnormal heart rhythms. Antiplatelet-prevent blood clots. Aspirin- help prevent strokes and heart disease. Beta-blockers-help reduce hypertension and congestive heart
Coronary artery disease affects the circulatory system. Chemically, this disease develops when blood vessels that are necessary for living become badly damaged. Cholesterol plaques become inflamed in the arteries. The most common signs and symptoms are chest pains which tighten the chest as if someone were standing on it. Shortening of breath also affects those with this disease because the heart is unable to supply enough blood. A major sign of this disease is having a heart attack. This indicates an artery that is completely blocked. This disease is caused by damaging the coronary arteries by smoking, diabetes, high blood pressure or high cholesterol. To diagnose this disease, medical physicians will perform physical exams and examine blood
The heart in many cases does not have a correct beat and can cause symptoms like fainting, chest pain, heart fluttering, etc (WebMd.com). In some cases, Arrhythmia can be major as it can sometimes cause immediate heart failure or cardiac arrest (MedicineNet.com). The last main condition of cardiovascular diseases are strokes (Centers for Diseases Control and Prevention). A stroke is a point where the brain has an interruption of a blood supply (usually are blood clots). Strokes can block the blood that flows to the heart and can result in heart attacks, cardiac arrest, dizziness, slurred speech, etc (Centers for Diseases Control and Prevention). All of these conditions are the main aspects of cardiovascular disease (WebMd.com).
Angina Pectoris is a disorder described by episodes of pain when the supply of oxygen to the heart is inadequate to meet the needs of the heart (Bruyninckx 2011). Hypoxia can be the result of three types of cardiac stressors:
Coronary Heart Disease (CHD) it is also know as Coronary Artery Disease. It happens when the blood vessels delivering to the heart develop blockage or are narrowed by plaque, which reduces the flow of the blood, oxygen and nutrients supplied to the heart. If this happens the person starts to feel chest pain (also known as angina pectoris) and then it lead to the person to have a heart attack. It is known to be the main factor to cause cardiac arrest and it can be fatal unless the heart is restarted in minutes.
A common symptom for myocardial ischaemia is angina - chest pain. Angina can occur in two forms: stable or variant angina (McCance & Huether, 2014, pg. 1154). Stable angina is caused by myocardial ischaemia. The symptoms are usually described as sensation of heaviness, pressing or squeezing pain, and sometimes may radiate to other places such as left shoulder, arm, lower jaw and neck (McCance & Huether, 2014, pg. 1154; Touhy, Jett, Ebersole, & Hess, 2012, pg. 270). On the other hand,
A recent systematic review of observational data (6 studies) found that the total mortality rate in angina patients was 2.8% to 6.6% per annum(121). At present it is thought that stable angina does not cause permanent myocardial damage. However prompt diagnosis and treatment is important to prevent further complications. Initiation of pharmacological intervention has been shown to retard plaque disease progression and to stabilise the surface endothelium(131).
Amlodipine has been established to block contraction and restore blood flow in coronary arteries and arterioles in response to calcium, potassium epinephrine, serotonin, and thromboxane A2 analog in experimental animal models and in human coronary vessels in vitro. This inhibition of coronary spasm is responsible for the effectiveness of Amlodipine in vasospastic (Prinzmetal's or variant) angina.
In summary, myocardial infarction is where there is a complete blockage of blood supply to the heart. In contrast, angina is chest pain or discomfort that usually occurs with activity or stress resulting from poor blood flow through the blood vessels in the
Heart attack occurs when a blood clot suddenly and completely blocks a diseased coronary artery, resulting in the death of the heart muscle cells supplied by that artery. Coronary and Coronary Thrombosis 2 are terms that can refer to a heart attack. Another term, Acute Myocardial Infarction 2, means death of heart muscle due to an inadequate blood supply.
A heart attack can occur for multiple reasons; angina is one of those reasons. Angina is an illness where not enough oxygen is getting to the heart, it cans be misdiagnosed
Angina pectoris is a symptom of underlying heart condition. It is characterized with symptoms such as severe pressing chest pain or heaviness radiating to the neck, jaw back and arm. The primary cause of angina pectoris is the imbalance between myocardial oxygen demand and the oxygen supplied by the coronary artery.
A heart attack, also known as a myocardial infarction, usually occurs when a blood clot forms inside a coronary artery at the site of an atherosclerotic plaque. The blood clot severely limits or completely cuts off blood flow to part of the heart. In a small percentage of cases, blood flow is cut off when the muscles in the artery wall contract suddenly, constricting the artery. This constriction, called vasospasm, can occur in an artery that is only slightly narrowed by atherosclerosis or even in a healthy artery. Regardless of the cause of a heart attack, the oxygen deprivation is so severe and prolonged that heart muscle cells begin to die for lack of oxygen. About 1.1 million people in the United States have a heart attack every year;