Crohn's Disease is Inflammation in the Digestive System Essay

Crohn’s disease is characterized by inflammation of segments of the GI tract. The parts of the tract where Crohn’s disease is most often seen are in the terminal ileum, jejunum, and right side of colon. Involvement of the esophagus, stomach, and duodenum is

For this week’s discussion topic, I have decided to talk about Crohn's disease. This disease causes inflammation of the bowels and the lining of the digestive tract. According to WebMD, Crohns is caused by an immune reaction against the intestinal tract and it can cause the small intestine to become inflamed, which hinders the absorption of nutrients (WebMD, n.d). Some symptoms that accompany Crohns disease are malnutrition, diarrhea, weight loss, bloating, and abdominal pain. According to the Mayo clinic serious problems can occur for people suffering from Chohns disease. Such problems include ulcers, colon cancer and bowl obstructions (The Mayo Clinic n.d.).

For my mini research paper I chose to interview one of my family members who currently suffers from Crohn's Disease which is a chronic inflammatory condition of the gastrointestinal tract. Crohn's Disease affects your digestive system and is believed to be caused by an overproduction of proteins produced by the immune system. The inflammation occurs when bacteria, food or other substances in the digestive tract are mistaken as a danger to a person's health and the body then responds by attacking the tissues of the colon. This process causes symptoms that include pain in the abdominal, cramping, and chronic diarrhea, usually soon after food is ingested. Upon being diagnosed, the doctor recommended making a few lifestyle changes to help alleviate

The immune system is the one that causes the inflammation in response to what is happening to the persons body. Having this inflammation would cause flare ups depending on what food you eat, leaving you with very frequent trips to the bathroom and severe abdonminal pain. Also, constantly having diarrhea can cause dehydration and make your appetite decrease as well. Crohn's disease does have some genetic link. According to the case study in class, antibiotics can sometimes trigger this response in the persons GI tract because it throws off the bacteria in our digestive system and we need that

Crohn’s disease, also known as regional enteritis, is one of two chronic inflammatory disorders that are referred to as irritable bowel syndrome (the other being ulcerative colitis; Lichtenstein, 2012). The difference between the two forms of irritable bowel syndrome (IBS) is based on the location within the gastrointestinal tract (Little, Donald, Craig & Nelson, 2008). Crohn’s disease may cause inflammation in any area of the gastrointestinal (GI) tract resulting in intestinal ulcers distributed segmentally, while ulcerative colitis is restricted to the colon and rectum (Kumar, Abbas & Aster, 2013).

Crohns diseases is an inflammatory disease of the GI tract. It differs from other forms of irritable bowel syndrome, because in can occur in any part of the GI tract. Most cases involve the small intestine. Some causes of this disease are lymphatic obstruction, infection, genetic predisposition, and an altered immune response to intestinal bacteria. Crohns disease causes ulceration of the superficial mucosa, and progresses its way to the deep mucosa. This will cause masses of granulation tissue to form. These masses are called granulomas. These granulomas will extend into the lymph nodes in the area. This will cause lymphatic obstruction. Edema, mucosal irritation, fissures, and abscesses occur. Neutrophils will infiltrate the area, and form

Crohn’s disease (CD) is an Inflammatory bowel disease (IBD), which is caused by the inflammation of gastrointestinal (GI) tract. IBD is known as the complex disease and the mechanism of progression remains as secret. Microbial imbalance expected to be the main cause of the inflammation. Gut microbiota takes a crucial importance in the intestinal diseases. Patients affected with the IBD are expected to have reduced biodiversity of commensal bacteria, such as Bacteroidetes and Firmicutes. Additionally, individual’s with CD were preassigned for antibiotics in between 2-5 years before diagnosed for CD rather than unaffected persons. Up to date, the medical treatment methods, which were using are immunosuppression medicals like prednisone, azathioprine,

For instance, Crohn’s disease(CD) is a chronic relapsing inflammatory bowel disease (IBDs), which affect the various areas of GI tract (from mouse to anus) and lead to abdominal cramps, weight loss, diarrhea, fever and the other symptom. According to the survey, Crohn’s disease was found to be more common in developed industrialized countries than less developed tropical countries because people who lived in developed areas have less chance of exposure to helminthes. Therefore, although the cause of Crohn’s disease is not fully understood, but it is consider to be related to environmental, genetic factor and autoimmune reaction. Medically speaking, Crohn’s disease is classified as an autoimmune disorder. Usually, there are many harmless and

Ulcerative colitis is a chronic inflammatory bowel disease that usually onsets early in life. Characteristics of ulcerative colitis are inflammation, multiple ulcerations and shedding of colonic tissues. This disease usually begin in the rectum and spread proximally to the colon; affecting the colon’s mucosa and submucosa. The treatment for this disease usually requires surgery and/or a lifelong drug regimen. (Hinkle, J. L., Cheever, K. H., 2013)

Crohn’s disease is not a curable disease. Crohn’s is an inflammation disorder that takes place in the gastrointestinal tract with symptoms from mild to severe. Victims of Crohn’s struggle with abdominal pain, diarrhea, weight loss, anemia, and fatigue. In some cases it can cause life-threatening complications. Colorectal cancer becomes an increased risk and patients often receive regular screenings.

Clinical manifestations for the two inflammatory bowel disease classifications are very similar however there are disparities which can help differentiate which disease process is occurring. In ulcerative colitis, the primary manifestations are bloody diarrhea and abdominal pain which can vary from mild lower abdominal cramping to severe, constant pain. In Crohn’s disease, the primary manifestations include diarrhea and crampy abdominal pain. Also, weight loss is very common in Crohn’s disease because inflammation of the small intestine causes nutrient malabsorption and deficiencies (Lewis et al.,

Inflammatory bowel disease(IBD) is a chronic lifelong disease that causes inflammation of the gastrointestinal (GI) tract. There are two most common types of IBD, Chrohn's disease and Ulcerative colitis. The GI is responsible for digestion of food, absorption of nutrients, breaking down, and elimination of waste from the body. The GI tract includes all of the parts of the body that digest food. It begins with mouth it follows down your throat into the esophagus,through stomach, small intestine, large intestine,rectum, and it finishes with your rectum. Chrohn's disease and ulcerative colitis have many things in common but they have some important differences. There is also a third type of IBD, indeterminate colitis can sometimes be diagnosed.

Crohn’s disease is chronic inflammatory disease of the intestines however affects the entire digestive system, from the mouth to the anus otherwise known as the Gastrointestinal Tract (GI Tract) [1]. Individuals affected by the disease are often young adults and adolescents aged 15 – 35 [7]. Crohn’s Disease is one of the two types of Inflammatory Bowel Disorders (IBD), the other being ulcerative colitis [3] and is usually located in the lower part of the small intestines and the upper end of the colon. There is no exact cause of this disease however various stimuli can cause the disease such as bacteria, genetics or Paneth cells [4]. Paneth cells are one of the four main specialised cell types found in the small intestine [6]

IBD, including both UC and CD, are not medically curable and the treatment process must be maintained throughout patient life. The primary therapeutic goals of IBD treatment are to (1) reduce the inflammation, that triggers the signs and symptoms, through inhibition of different targets (2) induce and maintain long time remission and (3) preventing and treating complications, which ultimately improve patient quality of life. The therapeutic choices of IBD include drug therapy and surgery. Pharmaceutical treatment options of IBD involve five major categories of medications, namely Aminosalicylates, corticosteroids, antibiotics immunosuppressive drugs and biologic agents.

In general, an infection, which provokes an inflammatory state in people with and without IBD, may cause every individual to have temporary GI inflammation and stir up symptoms of abdominal pain and diarrhea. Following the acute infection, most individuals reset their immune system and return to the previous state of controlled, low level inflammation. Individuals with various genetic abnormalities for IBD however, demonstrate an overly aggressive T-cell response wherein the immune system fails to reset itself and the colon does not return to its previous healthy state. Instead, there is a chronic inflammatory state, with a persistent imbalance between the factors that increase the body’s immune response and those that limit it. The onset and reactivation of disease are triggered by environmental factors that transiently break the mucosal barrier, stimulate immune responses or alter the balance between beneficial and pathogenic enteric bacteria.