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Influenza Infective Analysis

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cells and avoid the immune system response; also in human influenza infections, this glycan promotes binding of the virus to the glycans on erythrocytes; thus, facilitating the entry of the virus to the cells. Its overexpression on cell membranes is linked to cancer metastasis (Fuster and Esko, 2005; Severi et al., 2007). Therefore, the better understanding of how this post-translational modification occurs, will give insight into options for applications in biotechnology and medical treatments. A way of doing this is generating sialic acid analogues to be accepted by a SiaT enzyme. For instance, studies with various α-2-3 and α 2 6 linked sialyl galactosides analogues containing C9-modified sialic acids (produced by a coupled assay with enzymes:

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