It 's All About The Execution

Today we are in great need of a solution to solve the problem of the shortage of human organs available for transplant. The website for Donate Life America estimates that in the United States over 100 people per day are added to the current list of over 100,000 men, women, and children that are waiting for life-saving transplants. Sadly enough, approximately 18 people a day on that list die just because they cannot outlive the wait for the organ that they so desperately need to survive. James Burdick, director of the Division of Transplantation for the U.S. Department of Health & Human Services confirms, “The need for organ transplants continues to grow and this demand continues to outpace the supply of transplantable organs”. The

To further commend her argument, Satel analyzed the short term amd long term risks an organ donor faces and to a reasonably fact, “The truth is that a normal person can get along perfectly well with one kidney. The risk a donor runs is that his single functioning kidney will become deceased or injured and he’ll need a transplant himself—a highly unlikely event” (Satel 451).

Recent medical advances have greatly enhanced the ability to successfully transplant organs and tissue. Forty-five years ago the first successful kidney transplant was performed in the United States, followed twenty years later by the first heart transplant. Statistics from the United Network for Organ Sharing (ONOS) indicate that in 1998 a total of 20,961 transplants were performed in the United States. Although the number of transplants has risen sharply in recent years, the demand for organs far outweighs the supply. To date, more than 65,000 people are on the national organ transplant waiting list and about 4,000 of them will die this year- about 11 every day- while waiting for a chance to extend their life through organ donation

I watched Anthony Atala’s speech “Growing new organs” in TED Talks, and was convinced by Anthony that even engineered organ was very a controversial topic, it still brought benefits to patients who need tissue replacement. Anthony’s strongest delivery attribute was his language choices. He opened his speech by showing a story and research statistics of organ transplantation. For example, he pointed out: “every 30 seconds, a patient dies form diseases that could be treated with tissue replacement.” Anthony used the story and number wisely because he caught my attention and brought my interest to his speech. Also, Anthony used examples and stories of his own experience as a surgeon and a researcher. He not only established his credibility, but

“You see Mr. Benedikt my intentions were never to hurt anyone, I did not create the monster you saw.

Kidney disease has become more prevalent over the years, one in nine Americans has chronic kidney disease, resulting in the need for a kidney transplant. Kidney failure is caused by variety of factors resulting in damage of the nephrons, which are the most important functioning unit of the kidneys. Kidney failure can be broken down into three groups: acute, chronic, end-stage. Once kidney failure is irreversible, dialysis or transplantation is the only method of survival. To avoid a kidney transplant, one needs to be aware of the pre-disposing factors, signs and symptoms, available treatments, and proper diet.

The topic I would like to talk about today is called xenotransplantation. If you haven’t ever heard about xenotransplantation that’s okay, a lot of people haven’t. As you know many of the people who need organ donations need them because of new and old health issues. The worldwide demand for organs far surpasses the supply. A study done by the United Network for Organ Sharing in 2004 found that over one hundred thousand patients could have benefited from an organ transplant but only twenty-nine thousand were available. In the United States alone seventeen patients die each and every day while on the waiting list to receive a donor organ. Scientists have been trying to find a solution for the lack of donated organs.

Around the world there are millions of people, who suffer from kidney disease. However, globally there were 64,606 kidney-transplant operations in 2007. Donating Donating organs is one of the biggest problems around the world people need the donation of the organs, people who are dying at the hospital depend on it. Not everyone is able to afford a donation, they are really expensive, that's unfair in the sense that because someone has more money than some else they should be more important than someone else. The waiting list for a organ donor is also really bad, people have to wait years for a donation, because of how the list is people died like it said in the article that out of 64,606 people need it a transplant only 16,500 receive one.

As a result, a researcher from Wake Forest University named Professor Anthony Atala did a TED talk in 2011 on a demonstration on how to print a living human kidney, in which after the demonstration caused confusion in the crowd due to the research being in the early research stage and has never been previously used for a viable organ transplant (Lipson and Kurman 7). The TED talk demonstration was the world’s first introduction to the use of bio-printing viable organs for possible transplantation. In consideration of the TED talk, researchers have begun to harvest stem cells to 3-D print, in hopes to integrate with the existing tissue to produce viable organs and other body parts (Griggs 8). The bio-printing process has begun to have some success with clinical trials. In 2013, a surgeon named Doctor Paolo Macchiarini had a patient that is a 2-year old girl named Hannah from Illinois, who was born without a trachea (Griggs 9). Dr. Macchiarini created a bio-printed trachea from Hannah’s own stem cells and bone marrow, after in which he performed the 9-hour operation (Griggs 9). As a result, Dr. Macchiarini allowed Hannah to breath on her own and he will monitor her throughout her life, but for right now she is responding well to the transplant (Sifferlin 2). In result, bio-printing may begin to save and improve a lot of individuals’ life. Since, each day 18 people die in the

There are some medical conditions and situations which can cause an irreversible organ damage and failure. Currently, the only long term treatment for an end-stage organ failure is an organ transplant (Dalal, 2015). The most common transplant operation is the kidney transplant. Currently, in the United States, there are approximately 124,000 patients in the waiting list for organ transplant and there are not enough organs to keep up with the demands (Wall, Plunkett, & Caplan, 2015). Due to donor shortage only a small percent of patients would receive organs. Each year about 10,500 patients would die or become too sick for transplantation. Every 10 minutes someone is added to the transplant waiting list (Wall et al., 2015). Currently, organ

second that goes by, researchers are creating effective ways that can save more American lives. In the world of medicine today, there are many issues in health care we cannot solve. The lack of organs and tissues in America results in patients either dying or being put on waiting lists. There are no guarantees that the organ transplant will get to a person in time. Waiting for a perfect donor can take weeks and sometimes years for some patients. The lack of necessary organs is what has caused this organ transplantation crisis in America. This is what has driven many researchers to develop a new solution called three dimensional bio printing and tissue engineering.

At Niobrara County High School this school year, we have adopted the Four Disciplines of Execution by Stephen Covey as a model to develop and implement the Leadership focus in the high school.

Nine year old Amy has already had a rough start in life. She was born with an abnormal heart that hinders her everyday activities. Amy is unable to keep up with kids her own age because she often tires out easily. As a consequence, she has very little friends and is often alone. Amy is forced to take different medications everyday just to survive. Amy’s life consists of medicine, doctors, and constant hospital visits. However, Amy is due for a heart transplant that will save her life. The transplant goes extremely well and now Amy has the opportunity to go to high school and live a normal teenage life.  Like Amy, many lives are positively transformed due to the amazing surgery of organ transplants. Scientist and doctors are due the credit

Though sophisticated in nature, doctors for have actually performed organ transplants over a century, starting first with animal organs and then moving to human organs. For instance, in 1906, Dr. Mathieu Jaboulay, a French surgeon, treated two suffers of kidney failure by transplanting a goat kidney in one patient and a pig kidney into the other. While these transplants proved to be unsuccessful, resulting in the demise of both patients, Dr. Jaboulay’s work did lay the foundation for Dr. Yu Yu Voronoy, an Ukraninina surgeron that was the first to use a human kidney for transplantation. Again, these surgeries were unsuccessful. However, according to Watson and Dark (2012) but they did demonstrate “the deleterioius effect of warm ischeaemia”. Eventually,

One of the ideal treatments for organ failure in most of the cases is an organ transplant, which will help restore the function of the organ. Studies have shown that patient with kidney failure that are on a long-term dialysis have a higher mortality rate than patients with kidney transplants. However, there is a shortage of organ donors worldwide. According to the united network for organ sharing, as of October 30, 2015 there are 101,237 people on the kidney transplant waiting list and on the average there are over 3000 new patients added to the list each month. In the year of 2014, 4270 patients died while they were waiting for a kidney transplant. “Kidney regeneration is likely to provide an inexhaustible source of tissues and organs for immunosuppression-free transplantation. It is currently garnering considerable attention and might replace kidney dialysis as the ultimate therapeutic strategy for renal failure.” In spite of that, the anatomy of a kidney is very complex and that makes it difficult to regenerate the entire kidney.