Lh2 Case Study

Lupus “is predominantly a disease of young women (most commonly affecting women between the ages of 15–45) but can affect men as well” (Hughes & Sangle 2012). “Women of color (Asian and African American) are two to three times more likely to develop Lupus than Northern European women” (Hughes & Sangle 2012). It is a chronic autoimmune disease that affects many parts of the human body including the immune system, joints, skin, and organs within the body. Normally, the human body would produce proteins (antibodies) that protect the body from invaders such as viruses, bacteria and germs. In the human body afflicted with Lupus, the body becomes “autoimmune” and the body is unable to tell the difference between foreign invaders such as those named

Systematic lupus erythematosus (SLE) is a chronic, systemic, autoimmune disease. This condition causes the body to mistaken its own tissues and organs as foreign bodies and begins attacking them causing continuing inflammation and pain. (Huether & McCance, 2012) The cause of SLE still remains unknown, but it is possible that is inherited as a complex trait or caused by environmental stimuli. (S) Anyone is at risk for Lupus, but is more common among women than men and is more prevalent of African Americans and Asians. (National Library of Medicine 2010, para 2) This condition can be difficult to diagnose, as a patient must present a number of the recognizable symptoms. Depending on the location that Lupus presents itself in the body, the symptoms

Description: Lupus is an autoimmune disease which attacks the healthy body immune system. This immune disorder attacks the brain, kidneys, joints, skin, and other organs in the body.

Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July

Lupus also known as the systemic lupus erythematosus (SLE), is an autoimmune disease which signifies that the body’s immune system attacks the healthy tissues and organs by mistake. Lupus can affect any parts of the body including skins, joints, kidneys, blood vessels and as well as cause large inflammations in the organs that are affected by the disease. When an individual is diagnosed with Lupus, their immune system becomes hyperactive and begin to attack normal healthy tissues. The immune system makes antibodies which help fights against bacteria and viruses. Lupus cause the immune system to not able to distinguish between antigens and healthy tissues. As a result of not being able to distinguish between antigens and healthy tissues, the immune system starts to direct antibodies against healthy tissues. Lupus can be mild

function that selectively infects helper T cells” (545). My goal in this paper is to show the advances

Lupus nephrirtis is more commonly known as “lupus” is an inflammation of kidney caused by Systemic lupus erythematosus (SLE) , Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of immune tolerance to nuclear self-antigens. The deposition of autoantibodies along the glomerular basement membrane results in immune complex-mediated glomerulonephritis generally characterized by like malar rash, discoid rash, photosensitivity, oral ulcers, nonerosive arthritis, pleuropericarditis, renal disease, neurological manifestations, and haematological disorders.

Known as SLE, systemic lupus erythematosus is classified as an autoimmune disorder, which the immune system attacks itself , that might lead to the killing of cells. Autoimmune disorders causes the immune system to overperform and ends up attacking the body. During infancy in a person who has an autoimmune disease, “their immune system “forgets” that certain antigens in the body do belong there” (Thomas). When an autoimmune disease affects more than one organ in the body, it’s classifies as a systemic autoimmune disease. SLE “is a chronic disease that causes inflammation in connective tissues, such as cartilage and the lining of blood vessels.” (Genetics Home Reference) “SLE can potentially affect any system and organ of the body”(Thomas).

IL-10: works with IL-4 to counteract IFN-gamma and IL-12; comes from monocytes, TH2 cells, CD8+ T cells, mast cells, macrophages, B cell subsets

Systemic Lupus Erythematosus is a very rare and severe autoimmune disease. While the symptoms vary, lupus commonly affects the skin, joints, and mucous membrane (Brown, Bond, & Waldron, 2014). However, systemic lupus erythematosus (or lupus, for short) can become a multi-organ disease resulting in further complications. Because lupus is so rare and the symptoms vary, diagnosis is difficult and often does not occur until the disease is in its latter stages. However, in the detection of the disease, Brown, Bond, and Waldron (2014) express the importance of noticing certain common symptoms in young females, which are severe fatigue, mouth ulcers, headaches, rashes (especially those caused by the sun), and flitting arthralgasis (joint pain) and

Lupus Erythematosus, or Lupus, is a chronic autoimmune disease that causes the human body to attack itself. Autoimmune (meaning “self” immune) diseases result in the body being unable to distinguish between foreign threats and the body’s healthy tissues. Lupus has the potential to range from a mild aesthetic inconvenience to a life-threatening ailment. There is believed to be about five million people worldwide who are living with a form of Lupus (Ginzler & Tayar, 2015). While being a disease that transcends time, gender, age and ethnicity, significant medical progress was not made until the mid 20th century.

There are many varieties of lupus, but the most common one is Systemic Lupus Erythematous (SLE). SLE, commonly referred to as lupus, is a chronic autoimmune inflammatory disease that can affect all of the organs. There has not been a lot of research on this disease, but much of what is known about SLE is based on the signaling of the molecular abnormalities that is present in the disease (Signaling). It is believed that the cause of this disease is genetic, and triggered by unknown environmental stimulus. Although this disorder can occur in person, it is most commonly found among both African American men and women, especially women between the ages of fifteen and forty-five.

Systemic Lupus Erythematosus (SLE) is a genetic disorder. SLE is a type III hypersensitivity or an autoimmune hypersensitivity (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). Meaning that the body is attacking itself. In SLE a large number of autoantibodies circulate through the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies are deposited into the connective tissue all over the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies activate the complement system and cause inflammation and necrosis of the tissue that the autoantibodies are near (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). This usually takes place in many systems in the body. In order to be diagnosed at least four body systems have to be affected.

Memory T-cells- are long-lived subpopulations of Helper and cytotoxic populations that increase capacity to specific common antigens

There are many different types of diseases one’s body can suffer from, but one unique type of disease is an autoimmune disease. What makes autoimmune diseases different than other diseases is with an autoimmune disease the body ends up attacking itself. “The immune system inappropriately identifies its own proteins as foreign and mounts a response to destroy these self-proteins” (Linton, 2016). One in particular autoimmune disease is Systemic Lupus Erythematosus, also known as SLE. SLE has a debilitating impact on the body, is defined by a very distinctive mark on the face, difficult to diagnose, and currently has no cure.