Livedoid Vasculopathy (LV)

531 Words3 Pages
Livedoid vasculopathy (livedoid vasculitis or LV) is a chronic, recurrent and painful disorder of the cutaneous microcirculation. This dermatosis is relatively rare and occurs most commonly in young to middle-aged women in whom the lesions are often located in the distal lower extremities and feet. LV is clinically outlined by a triad of symptoms which need not occur simultaneously. These symptoms are livedo racemose, painful ulcerations and scars called atrophic blanche. The pathophysiology of LV is not well understood but the condition is categorized as either primary or secondary. The primary form appears to show no association with any other diseases, whilst the secondary form is associated with diseases characterized by a hypercoagulable state i.e. thrombophilia. Such diseases may arise due to a fibrinolytic disorder (heterozygous protein C or S deficiency, Factor V Leiden mutation), prothrombin gene mutation, or hyperhomocysteinemia. In some cases of LV, there appears to be an association with connective tissue disorders such as systemic lupus erythematosus (SLE), cryoglobulinemia and Antiphospholipid syndrome (APS).…show more content…
This causes a marbled discoloration of the skin which appears lacy – this is associated with livedo

    More about Livedoid Vasculopathy (LV)

      Get Access