Malignant melanoma is a serious type of cancer that effect skin cells. The incidence of cutaneous malignant melanoma has rapidly increased over the past 50 years in predominately fair-skinned populations and have spread in KSA and worldwide countries
Worldwide incidence:
Malignant melanoma is the 19th most common cancer worldwide, with around 232,000 new cases diagnosed in 2012. Skin cancer incidence rates are highest in Australia/New Zealand and in North America but lowest in South Central Asia, but this partly reflects difference data quality worldwide. The rates have become rather stable in recent years. Indications of a stabilization or decreasing trend were noticed mainly in the youngest age group (25-44 years). Rates have been rising
Although there are several types of skin cancer, the most aggressive form is melanoma. This cancer of the skin involves mass replication of the pigment producing melanocyte cells, which are located in the epidermis, below the basal layer. There are several factors involved with the onset of melanoma including, exposure to ultraviolet rays, genetic predisposition, numerous nevi (moles), immunosuppression, and environmental exposure to carcinogens.
Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and
Melanoma is a serious type of skin cancer, causing up to 75% cancer-related deaths and is usually occurs due to exposure to UV rays of the sun. The chances are increased with sunburn episodes especially during childhood. It developed from the pigment cells known as melanocytes, a layer of cells producing melanin which protects against the damaging rays of the sun. Sometimes, these pigment cells increase in size and become cancerous melanoma. It didn’t show any particular symptoms, however, it is related to the changes associated with moles, gives ‘ABCDE’ warning signs i.e. Asymmetry, irregular Border, uneven Colour, Diameter, evolution.
There has been cases where places on your body that don't receive exposure to sunlight has been diagnosed with melanoma. The damage of skin may take place in the few years before the start of the cancer. Children and young adults often get sun exposure that might not result in cancer until many years later. The epidemiology of melanoma is diagnosed at 70 percent of curable stages. However, if melanoma is diagnosed later, the patient has a decreased chance of living. An estimated incidence rate of melanoma has been 3–7% per year for Caucasians. Melanoma is the fifth most common cancer in men and the seventh in women. The pathogenesis of this disease is a neoplasm of melanocytes or a neoplasm of the cells that develop from melanocytes. The treatment for melanoma can be done in stages. Stage zero is a surgery to remove the area of abnormal cells and a small amount of normal tissue around it. Next, stage one of the treatment is having surgery to remove the tumor and some of the normal tissue around it. Stage two of treatment finding the lymph nodes and taking a biopsy. If cancer is found in the sentinel lymph node, a second surgery would need to be carried out to remove more nearby lymph nodes. Then, for stage three, a doctor may take skin grafts to cover the
Malignant melanoma is the most commonly seen skin cancer and it has the highest number of deaths among diseases of the skin (Friedman, Rigel, Kopf and Polsky, 2005). Among the many factors that cause this cutaneous cancer genetic modifications, viruses, carcinogens and excessive exposure to ultraviolet rays are the most commonly occurring (Friedman, Rigel, Kopf and Polsky, 2005). Malignant melanoma affects all areas of the skin and the disease forms in melanocytes, which are the cells in which pigments (melanin) are synthesized (Melanoma Treatment). The cancer has its origin in the epidermis and affect squamous and basal cells. The disease usually affects the trunk, arms and legs but can also be present in the eye, affecting the
“Skin cancers are the most prevalent form of cancer in the Unites States An estimated 11,790 people die of skin cancer each year, 8700 from malignant melanoma” (Huether, McCance, 2012, p. 1058). Since melanoma is the most prevalent form of cancer, it is important to understand what causes it, what it does, who is at a higher risk, and possible treatment routes.
Melanoma, a type of skin cancer that normally starts in the melanocytes, a type of skin cell. In the past few years, doctors have noticed a spike in the number of cases of Melanoma. Many things can cause Melanoma, such as sun exposure or even laying in tanning beds. The use of tanning beds is the one of the large reasons why doctors believe this spike has occurred. Men are more venerable to skin cancer than women are, although women who tan are obviously more prone to getting this type of skin cancer. In the past few years, doctors have seen a rise in middle-aged women. Also compared to the 1970s doctor’s suspect that the way our clothes and bathing suits are designed now days could have something to do with this increase. The bathing
In 2011, there was an estimated 65,647 patients diagnosed with melanoma, and 9,128 deaths from melanoma in the United States.[1] Rates for new melanoma of the skin have been rising on average 1.8% each year from 2002 to 2011.[2] It has been estimated that 1 in 75 persons born in the year 2000 will develop melanoma of the skin during their lifetime.[3] Like most cancers, the outcome of melanoma depends on the stage at diagnosis, which makes the early detection and treatment of melanoma important.[4] However, in the United States approximately 80% of biopsies performed in a primary care setting are benign.[5] Technologies such as RCM may have the ability to reduce invasive diagnostic procedures such as a biopsy or excision associated with
Melanoma being the austere form of skin cancer which can be fatal in most cases. Mayo Clinic’s article on the diseases and conditions of melanoma gives good clarity as to what is actually occurring, and how it forms. The article states that what causes melanoma is unclear and hasn’t been discovered but what takes place is the melanocytes that generate melanin cells is agitated by unknown causes which results in the change in pigmentation of the skin or a change in a current mole already present on the skin. Strategies that can help you detect the symptoms of melanoma consist of the letters “A- E meaning A: asymmetrical shape regarding moles, B: irregular boarders, C: change in color, D: diameter, and E: evolving” (Mayo Clinic Staff 2016) Melanoma can appear not only on the skin but underneath a person’s nail, it can affect their eyesight and rarely their internal organs such as the mouth, urinary tract, and digestive tract called mucosal melanoma. These are noted to be hidden
Melanoma is a very serious type of skin cancer and can be extremely dangerous if it’s not taken care of properly. Melanoma usually develops in the melanocyte cells when the skin has been exposed to ultraviolet radiation from tanning beds or from being outside in the direct sunlight for too long or over a long period of time. When unrepaired skin DNA becomes too damaged, it can trigger a mutation in the cells which leads to the skin cells to rapidly multiply, turning into the cancerous growths. In some cases, melanoma can form in the eyes, nose, mouth, genitals and, in rare situations, form in the intestines (Mayo Clinic).
"The rates of skin cancer have expanded consistently since the 1920s uncovers the risk of the American fixation on getting a "solid" tan. Skin tumor is an infection where growth (harmful) cells are found on the external layer of the skin (epidermis). The three sorts of cells found in the epidermis are squamous cells, basal cells, and melanocytes. These cells in time develop to be carcinogenic. Consequently, the three sorts of skin tumors are squamous cell, basal cell, and melanoma. Melanoma is the deadliest and dangerous kind of growth. The quantity of individuals with melanoma has ascended in Scotland from 3.5 in 1979 to 10.6 for each 100,000 in 1998 for men and 7.0 to 13.1 for ladies. (Mill operator 945) Squamous cell and Basal cell skin
The outcome of interest in this study was to identify a population at a higher risk for malignant melanoma, and develop a clinical screening tool that could earlier detect malignant melanoma in this high-risk population. Another outcome of interest was to determine the effectiveness of total skin examination in detecting malignant melanoma in these high-risk groups, with the hope of detecting the melanoma earlier so that patients can be treated more effectively. This would be important to patients because the earlier detection of malignant melanoma from screening high-risk populations would allow for earlier treatment, thus hopefully decreasing the mortality rates in patients with malignant melanoma.
Melanoma can spread quickly to other parts of the body and organs. In addition, it can begin wherever there is pigment, most appear spontaneously, and about one-third develop from preexisting moles. An estimated 9,940 people will die of melanoma in 2015 according to American Cancer Society (2015) (6). Although it accounts for less than two percent of skin cancer cases, melanoma composes the vast majority of skin cancer deaths. Indeed, certain populations are at a greater risk of getting skin
The skin cancer is long term disease.it is most widely recognized of all diseases. The melanoma indicates under 2% of growing skin cases however there is huge greater part of skin cancer passings.the recent research the Cancer Society’s identified melanoma in the newzealands for 2015:
In the scholarly article “Influencing melanoma prevention”, Calianno explained the significance of the growing amount of people that are being diagnosed with cancer (2011). The article states risk factors that are indicative of people more susceptible to getting cancer, but also how early detection can be categorized. These risk factors include genetic predisposition, skin type, environment…large congenital moles, or extensive freckles (Calianno, 2011, p. 6). There are four main types of melanoma included but the most common is