Marburg Virus

Hand, foot, and mouth are parts of human body have the highest change to get contagious infection. There are many viruses but Enterovirus groups, (most common is the coxsackie virus) is the main factor. These viruses can spread through direct contact from person to person especially with those have bad habits such as: unusually washed hands or surfaces contaminated with feces. An infected person’s saliva, stool, or respiratory secretions can transmit the infection.

The Ebola virus can be compared to the Marburg virus. Marburg is a hemorrhage fever. It is mostly found in African Monkeys but can spread to humans. It first affected Marburg, Germany. It was spread by monkeys. 329 people died and this disease was thought to be eliminated.

* The Reston Ebolavirus was discovered during an outbreak of Simian hemorrhagic fever virus (SHFV) in crab-eating macaques from Hazleton Laboratories (now Covance) in 1989. Since the initial outbreak in Reston, Virginia, it has emerged in Siena Italy, Texas, and among pigs in the Philippines. Despite its status as a Level-4 organism, it is non-pathogenic to humans although hazardous in monkeys.

Richard Preston’s novel The Hot Zone, was based on a true story about the origins and incidents involving viral hemorrhagic fevers, mainly the Ebola and Marburg viruses. It primarily focuses on the Ebola virus’ first documented outbreak during the 1980s. As you read The Hot Zone, you will notice that it has been divided into four individual segments. The first segment looks into the history of filoviruses, and how AIDS emerged. The novel begins with Charles Monet, an elderly man who travels to Kitum Cave in Kenya. After coming in contact with an odd liquid substance, he begins to experience symptoms of the Marburg Virus (abbreviated as “MARV”), which includes; headaches, backaches, internal organs failing, and excessive bleeding. Monet travels to the Nairobi Hospital and ends up infecting the young Doctor that treated him. Years after Monet’s passing, a young pathologist named Nancy Jaax is introduced. Her story was told in her point of view as she describes the Introduction to Viruses, Biosafety Levels, and

The Iowa Department of Public Health has confirmed a rare case of disease caused by the Jamestown Canyon virus. In addition, there are two cases has been reported to the Iowa’s Health Department about West Nile Virus, which is also an illness spread by mosquitoes, along with Jamestown Canyon virus. According to the author, people who are infected by these two viruses will experience: “fever, headache, and flulike illness.” Luckily, however, “the patients who had Jamestown Canyon virus and West Nile virus are slowly recovering.”

In his book, The Hot Zone, Richard Preston focuses on an outbreak of the Ebola virus in Reston, Virginia and in multiple places in Africa. To show how dangerous an outbreak can be, Preston examines, in great detail, various other viral outbreaks, including Marburg. Preston begins by talking about a fifty-six year old Frenchman named Charles Monet who ends up breaking out with a treacherous disease called Marburg. This wasn’t known until his doctor, Dr. Shem Musoke, ended up testing positive for Marburg after Monet`s infected blood went all over Doctor Musoke as Monet was dying. Musoke survived his outbreak with Marburg.

First discovered in the 1970’s, the ebola virus was contained to West Africa (“About Ebola Virus Disease”). Villagers’ diets consisted primarily of the resources readily available. Among these resources were fruit, vegetables, and animals, namely monkeys. Monkeys carried the ebola virus, and when people ate them, without proper cleaning and cooking techniques, they became infected. Ebola, formally known as Zaire Ebola Virus, is transmitted through bodily fluids like saliva, blood, semen, breast milk, mucus, sweat, tears, feces and urine. ("Ebola in West Africa."). Since it was introduced to a third world country, where hygiene is not regarded as important as survival. Without education, protection and segregated sewage, the virus began to spread. In days people were dying after spreading the virus to those closest to them (Waterman). The bodies, though dead, were still harboring the virus and

The Hot Zone, written by Richard Preston is the true and dramatic story of the outbreaks of the frightening, unknown and incurable filoviruses; Marburg, Ebola Zaire, Ebola Sudan and Ebola Reston. This book covers the first documented outbreak of the virus and continues to cover more outbreaks over the course of 23 years. These sisters viruses are highly infective and destroyed entire communities throughout Africa with the deaths of 50- 90% of their victims. The effects are similar and horrifying with the viruses penetrating every tissue and organ in the body of a person, primate or other animal. This book takes place in the late 1980s and is based on an outbreak of Ebola in a monkey house in the quaint town of Reston, Virginia. Richard Preston incorporates tales of several outbreaks that occurred in Africa years before to describe the potential destruction that the filoviruses could

I recently read an article written in The NEWYORKER called The Deadliest Virus by Michael Specter. The article talked about the Avian Flu virus, also known as “bird flu”. In the article, Specter interviewed many people, but the most important person, in my opinion, is a virologist who conducted research on the Avian Flu, Ron Fouchier. This article raised many ethical questions. The questions are as followed: Should research be conducted on this virus? Does Fouchier’s research pose a threat? Does the risk of the work outweigh the benefits of the research?

Herpes viruses have a history of infecting different animals in the past. The herpes-b virus is carried by numerous species of macaque monkeys, which are believed to be a natural host for the virus. An increasing population of drifting monkeys in Florida takes a herpes virus that is deadly to people. The herpes-B infection is sporadic in individuals, but if it does happen, it could lead to serious brain injury or death when the individual is not treated immediately.

More active disease surveillance needs to occur. This means that health care workers should be encouraged to document and report those they think have been exposed and their contacts. In more effectively reporting suspected cases, Ebola response teams are better able to promptly follow-up, transfer to isolation centers, and assess the scope of the epidemic (Matua, Van der Wal, & Locsin,

Starting with one of the four filoviruses mentioned in the book, Preston provided us with the story of Charles Monet, an amateur French naturalist who died a gruesome death after contracting Marburg virus following a trip to Mount Elgon. Marburg is brought up in the story several times as a close relative of Ebola, having similar symptoms and equal danger. Throughout the next several chapters, different strains of Ebola are reviewed; the Sudan

Smallpox is caused by the variola virus an extremely contagious disease. That can be spread through any type of contact with the virus. The virus is a member of the genus Orthopoxvirus, in the Poxviridae family. Smallpox has been considered eradicated in the United States since 1972. Virologists have speculated that it evolved from an African rodent poxvirus 10 millennia ago. The name is derived from the Latin word for "spotted" and refers to the raised bumps on the face and body of the patient. (Medscape.com) Smallpox has been to blame for the extinction and almost extinction of many cultures. The disease has been used as biological warfare since the beginning or war. At times,

​The origin of the disease has been described at the end of the movie where we find out that a bat with a virus known as paramyxovirus that infects a pig. The pigs that are for human consumption were located near a forest that was being cut down. The pig in turn infects human beings of the earth through a chef. The agent which is very infectious is known as MEV-1 and its potential spread is estimated at 6-7 which suggests that the virus is highly transmissible from one person to the next. The virus has been compared to that of a smallpox virus with a mortality rate of up to 30%.

A number of studies have supported the theory that the virus had originally occurred in animals previous to human infections.5 The MERs-CoV virus is a type of coronavirus that has been known for infecting both birds and many species of mammals. These types of infections are commonly referred to as zoonotic diseases because the pathogens are able to be transferred from animals to humans. Zoonosis can happen with or without a vector in order to spread the infection. Although the exact origin of the MERs-CoV infections is unknown, there has been convincing research performed that has found related types of coronaviruses in bats and camels. According to the Center for Disease Control and Prevention, the coronavirus is found in multiple species and can cause respiratory illness and gastrointestinal upset.