Metastatic Cancer Research Paper

“Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems (NCI, 2013).” Cancer is of many diseases. It originates from the organ in the body and/or from the part of the body that is affected, for example breast cancer. Breast cancer is mainly common among women, except for skin cancers. “Breast cancer occurs when cells in the breast divide and grow without their normal control (Komen, 2014).” The

Cancer begins in the cells, which combine to make tissue in the body. Healthy functioning cells grow and divide to form new cells when cells are needed. Normal cells will grow and then die to make room for new cells. Cancer cells work differently because new cells form when the body does not need them and old and damaged cells do not die. Instead, the extra cells build up and form tissue called a growth or a tumor. Nodules are growth on the thyroid. The two types are benign nodules, which are not cancer and malignant nodules, which are cancer. Cancer cells are very dangerous because the cells can separate from the original tumor and spread to other organs. Metastasis is the spreading of cancer and can result in the damage of organs.

Distant metastases are mostly identified in patients of osteosarcoma with the estimation of about 85% after surgery. Mostly they occur in lungs however it may also metastasizes to soft tissues and other different bone. Osteosarcoma is lethal because of pulmonary metastasis with widespread progression that leads to respiratory failure. Tumor metastasis and invasion are multistep complex process in which tumor cells alter cell–extracellular matrix (ECM) associations at the primary tumor site to invade adjacent tissues and thus translocated through the vascular vessels to other systems to form secondary tumors there. MMPs are family of proteolytic enzyme that plays an essential role in tumor metastasis and invasion by breaking the ECM and basement

“Cancer is the uncontrolled growth of abnormal cells in the body. Cancer develops when the body’s normal control mechanism stops working. Old cells do not die and instead grow out of control, forming new, abnormal cells. These extra cells may form a mass of tissue, called a tumor. Some cancers, such as leukemia, do not form tumor”.(‘What is cancer?”) A tumor is the swelling of a part of the body, generally without inflammation, caused by an abnormal growth of tissue, whether benign or malignant. Benign, if the cells are benign they are not cancerous. It won't invade nearby tissues or spread to other areas of the body. Also, some types of benign tumors such as intestinal polyps are considered precancerous and are removed to prevent them becoming

A tumor, also known as a neoplasm, is an abnormal mass of tissue which may be solid or fluid-filled. A tumor does not mean cancer - tumors can be benign (not cancerous), pre-malignant (pre-cancerous), or malignant (cancerous). There are many different types of tumors and a variety of names for them - their names usually reflect their shape and the kind of tissue they appear in. A tumor is a kind of lump or swelling, it does not necessarily pose a health threat. Tumor are not necessarily cancerous, Benign tumors cannot spread, fibroids are benign tumors that grow on fibrous or connective tissue, lipomas consist of adipose tissue, a premalignant tumor is one that is not yet cancerous but is about to be, Cancerous tumors are referred to

Metastatic disease may be an incidental finding in asymptomatic patients. It may present with nonspecific symptoms such as malaise or weight loss, and it may present with symptoms and signs related to the metastatic site as dyspnea, lymph node enlargement, bone tenderness, or signs of increased intracranial tension.

Metastasis atic growths are is the movement of growths of the neoplastic cells in locations that are secondary to the primary site of origin. Benign neoplasms are unable to form metastatic growthsn. While any space-occupying growth is referred to as a tumor, they may or may not be neoplastic. And neoplastic tumors may or may not be malignant. The term “cancer” refers to malignant neoplasms; the neoplasms that can successfully produce malignant growth at sites other than the origin tissue of the neoplastic cells. The naming of neoplasms is primarily dependent on whether they are malignant or benign and the original tissue type of their origin. whether they are of epithelial or mesenchymal of origin. Benign neoplasms are named by adding the suffix –oma to the tissue of origin. So a benign fibrotic neoplasm is a fibroma, a benign growth of adipose tissue is lipoma, a benign tumor of a gland is an adenoma, and so on. Malignant neoplasms of mesenchymal origin are named by adding the descriptor of sarcoma to the tissue of origin, such as fibrosarcoma, adenosarcoma, and

From the genetic point of view the progression of tumor that culminates with metastasization, occur as a result of activation of oncogenes and/or by the inactivation or inhibition of onco- suppressor genes(Fearon, 1990)

Cancer is a terrible class of diseases that is characterized by abnormal cell growth. Cells can experience uncontrollable growth if there are damages or mutations to DNA. Specifically, the alteration of genes involved in cell division is responsible for the hypergenesis. When damaged cells divide uncontrollably they form lumps or masses of tissue called tumors. These tumors can either be malignant or benign. Benign tumors generally stay in one spot and demonstrate limited growth. Conversely, malignant tumors exhibit angiogenesis and invasion. Invasion is a process by which cancerous cells move throughout the body and grow into surrounding healthy tissues while angiogenesis is a process by which cells divide and propagate continuously making

Any type of cancer begins in the cells. The cells are the basic building blocks that’ll make the tissue. If the process of cell growth goes wrong then new cells will form with in the body. Whenever the cells form within the body it’s because the body no longer needs them cells because they’ve became old and damaged, and old and damaged cells won’t die. When the damaged cells won’t

Metastasis is the process by which cancer cells spread towards different sites within the body. These anew pathological sites are metastases. Metastic processes are common during the final stages of cancer and spread via the lymphatic system, bloodstream or through both pathways. Hotspots for metastases include the brain, lung, bones and liver(Klein, 2008, Chiang and Massagué, 2008).

This paper talks about the discovery of cancer cells, and how different doctors and physicians have tried to get a better understand of it over the centries. The causes of and treatment plans as well as trying to prevent cancer. Breast cancer, happened to be the first cancer cell discovered, so this paper is going to concentrate specifically on breast cancer. It will talk about the different treatment plans that can be considered as well as ways to prevent breast cancer.

Cancer is a disease/ a malignant growth or tumor caused by an uncontrolled division of abnormal cells in a part of the body. Cancer develops when the body’s accustomed control mechanism ceases to work. Cells grow out of control, forming new, abnormal cells. These extra cells may form an abundance of tissue. This abundance of tissue is called a tumor. Some cancers, such as leukemia, do not form tumors. Cancer can form anywhere on the human body.

Cancer starts when the cells of the body start to develop out of control. The cancer cell turns into a cancer cell because of the changes their DNA. Cancer cells travel through the body, making replicates (forming tumors which are balls of cells) of itself that crowds out the normal cells or tissues. There are multiple signs of cancer, such as: weight loss, fever, fatigue, pain, skin change. There are cancer treatments that can either slow down the cancer or supposedly wipe it clean. http://www.cancer.org/cancer/cancerbasics/what-is-cancer

Cancer is a kids of diseases which is the cells divided abnormal and uncountable. That cells can invade to other tissues of human’s body through blood and lymph systems.( MediLexicon International) Cancer is the general term of that disease, actually is not just one disease. There are more than a hundred different types of cancer. Those kids of diseases are most orinage by the organ.