Multiple Sclerosis : An Autoimmune Disease Of The Central Nervous System

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)

Multiple Sclerosis is a disease that attacks the myelin coating over the nerve receptors in your brain and spinal cord. Myelin is a fatty material that coats and protects the nerves in your brain. These nerves send signals to the rest of your body enabling

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

If you know anyone with Multiple Sclerosis or MS, you would know how terrible the disease is. Multiple Sclerosis is an inflammatory disease in which your immune system attacks the nerve cell covers in the brain and spine are damaged. The nerves in the body eventually deteriorate and it is fatal. According to the National Multiple Sclerosis Society, the cause of Multiple sclerosis is still unknown. There is not a cure at the moment for Multiple Sclerosis, but there are treatments that can speed recovery when attacked by the disease (Mayo Clinic). Scientists are under the impressions that there are a few factors that may come into play. They say that when they discover the exact cause of Multiple Sclerosis it will be easier to find a way to treat the disease or maybe even stop it from happening at all. (National Multiple Sclerosis Society)

Multiple Sclerosis is an autoimmune disorder which is characterized by multiple areas of scarring to nerve fibers of the CNS. It often affects people between 20 to 40 years. Currently there are about 1.1 million people suffering from multiple sclerosis. Like most of the autoimmune diseases females are more affected than males in this disease. Multiple Sclerosis effects the central nervous system (brain and spinal cord). The disease commences with a discrete attack known as CIS (clinically isolated syndrome), which may attack any area of the CNS but mostly attacks either the brain stem, optic nerve or spinal cord.

different. Everyone has different symptoms and treatment that works for them. Not one case is

Imagine a world where you have been diagnosed with a disease that has no cure and left your world upside down because your body has turned against you. Multiple Sclerosis is a potentially debilitating disease that is caused by the body’s immune system attacking the Myelin sheath of nerve fibers throughout the body (Multiple Sclerosis, 2017). This, in turn, creates miscommunication or lack of communication in the body, which can eventually lead to permanent disability. For those who are diagnosed, there are various symptoms to watch for and while not curable, it is treatable.

The first and most common type of MS is Relapsing-remitting multiple sclerosis (RRMS). This type of MS is characterized by periods of damaging relapses followed by extending periods of remission without symptoms. It is believed that the relapses are caused by acute inflammation that appears randomly. Most individuals who are diagnosed with RRMS transition to secondary progressive multiple sclerosis (SPMS) as their symptoms worsen from recurrent relapses. SPMS is described as the progressive decline in neurological function that may or may not have periods of remission. A less common form of this disease is primary-progressive multiple sclerosis (PPMS). Individuals with PPMS suffer from continual progression of disability without any periods of remission. This is caused by the gradual degeneration of neurons as opposed to continual periods of acute inflammation. This type of MS is rare, only affecting around 10% of those diagnosed with the disease. The rarest form of MS is progressive-relapsing multiple sclerosis (PRMS). This type of MS is the most debilitating form of the disease. Individuals suffer from a steady decline in neurological function from continual acute attacks of inflammation. In this form of MS, there are no periods of remission and disability worsens, often without any recovery (Waxman,

Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS) that typically is diagnosed in the second or third decade of life. Normally, nerves are enclosed in myelin sheaths that help facilitate transmission of nerve impulses within the CNS and the peripheral nervous system throughout the body. In patients with MS, the myelin sheath is damaged and eventually degenerates, causing patches of scar tissue called plaques or lesions to occur anywhere randomly on the myelin sheath (Ruto, 2013). This results in impaired nerve conductivity, which interferes with message transmission between the brain and the other parts of the body. As a result, impulse transmission is altered, distorted, short-circuited, or completely absent. This interference in impulse transmission creates muscle weakness, muscle imbalance, and possibly muscle spasms with partial or complete paralysis. Multiple sclerosis also can result in visual impairment and alteration of cognitive abilities, as well as pain, numbness, or tingling sensations (Ruto, 2013).

Multiple Sclerosis (MS) is a condition where myelin forms scar tissue and disfigures nerve impulses. This is an example of a deviation from normal physiology found in the nervous system. MS is the result of the immune system atypically attacking myelin and nerve fibers within the central nervous system (CNS). When the myelin and nerve fiber are damaged, it can cause the signal to be disturbed or disfigured. The damaged scar tissue (sclerosis) gives the disease its name. The symptoms of MS can range anywhere from pain and fatigue to tremors and

Multiple Sclerosis is hard to diagnose; early signs of MS are non-specific and the individual may appear to have another disease (“NMSS,” 2012). It is still unclear how multiple sclerosis is inherited, although the disease does appear to be passed down over family generations. Most people exhibit symptoms for the disease between the ages of 20-40 years old; symptoms can vary depending on the individual and can range anywhere from mild to extremely painful (“NINDS,” 2015). People manage their symptoms in different ways including prescription

Multiple Sclerosis is an autoimmune disorder affecting movements, sensation and bodily functions. The cause of MS is by the myelin sheath being destroyed in the brain and spinal cord. The immune system attacks myelin sheaths which is a fatty substances that surrounds the nerve axons that makes it possible for the transmission of nerve impulses. When the myelin sheath are destroyed the nerves impulses that are being triggered to the brain and spinal cord get out of disrupted that provoke the messages to become slower and less efficiently. There are four types of MS people could experience which are Relapsing-remitting multiple sclerosis (RRMS), Secondary –progessive multiple sclerosis (SPMS), Progressive-relapsing multiple sclerosis (

the fact that there are many more cases in the northern latitudes than in the