preview

On Certain Derivatives Of Dihydroanthracene Summary

Decent Essays

Drug Discovery Pioneer Exercise Ryan Stephens 21276916 Felix Hoffmann was born January 21, 1868 in Ludwigsburg, Swabia, Germany. Although his family did not come from a medical or scientific background (his father was an industrialist), it has been said that Hoffmann was searching for a drug to relieve his father’s arthritis pain. Hoffmann studied at the University of Munich and in 1891, Hoffmann graduated magna cum laude (“with great praise”) with a degree in Chemistry. Two years later in 1893, he received his doctorate, also magna cum laude, after completing his thesis, “On Certain Derivatives of Dihydroanthracene”. Hoffman is most well-known for his role in the discovery and creation of Aspirin while at Bayer. He started his journey …show more content…

• it is often used to help prevent heart attacks, strokes and blood clots because of its antiplatelet effect Aspirin has had a profound effect on clinical practice Aspirin is now used post-surgery after percutaneous coronary interventions to prevent blood clots. Aspirins usability has created a trickledown effect allowing people being able to control their own pain with the drug, it has would resulted in less people having to come to clinical practices with more minor problems subsequently therefore allowing doctors to focus on serious cases. Also, as Aspirin reduces pain, fever and inflammation, it has reduced the amount of time patients stay in hospitals to recover. There has been little evolution and innovations in terms of Aspirin’s formula. It has not been changed since Hoffman’s discovery! However its form has been improved whilst originally sold as a powder, in 1915 Aspirin was produced as a tablet. Also, while the drug itself has not been modified, the knowledge about it has. It was not until the 1970’s that scientists began to understand how aspirin works, and in 1982, the scientist responsible for the findings, Professor Vane, won the Nobel Prize for Medicine for his …show more content…

The end of Hoffman’s story unfortunately ends quite sadly. Although his discovery had such a profound effect on the world Hoffman’s legacy is rather understated, to this day the inventor of Asprin has remained to some extent faceless. Having never married, nor had children, Felix Hoffmann died February 8, 1946 in Switzerland, out of the public eye. References Chemheritage.org,. 2014. 'Felix Hoffmann | Chemical Heritage Foundation'. http://www.chemheritage.org/discover/online-resources/chemistry-in-history/themes/pharmaceuticals/relieving-symptoms/hoffmann.aspx. Communications, Bayer. 2014. 'Felix Hoffmann - Bayer'. Bayer.Com. http://www.bayer.com/en/Felix-Hoffmann.aspx. Drugs.com,. 2014. 'Aspirin Uses, Dosage, Side Effects & Interactions - Drugs.Com'. http://www.drugs.com/aspirin.html. Inventors.about.com,. 2014. 'History Of Aspirin'. http://inventors.about.com/library/inventors/blaspirin.htm. Rainsford, K. D. 2004. Aspirin And Related Drugs. London: Taylor &

Get Access