Prodair Respiclick Research Paper

When an asthmatic takes an inhaler “Albuterol sulfate”, the medication works by reducing the inflammation in the airway paths “bronchi and bronchioles” of the lungs, allowing the patient to breath without constriction or symptoms of asthma.

Then there’s the “Afternoon” inhaler, which provides a steady buzz from a hybrid of the two.

I press the mask to my face gasping for air. The abuterol steaming throug my over-used nebulizer does nothing to ease my tightening chest. I've lived with

Subsequently, it increases pulmonary pressure and pushes fluids in the capillaries out into the alveolar spaces resulting in congestive heart failure. This series of events can demonstrate fluid overload in the lungs that can cause dyspnea, which may affect an individual overall functional capacity and thus result in cardiopulmonary deconditioning. Pan et al. (2014) describes this medicine as a direct adrenergic agonist that acts exactly on β1 agonist in the heart and partly β2 receptor (lungs); it produces an active contraction of the ventricles to increase the heart’s cardiac output and degrades pulmonary resistance minimally through vasodilation hence, decreasing pulmonary congestion.

Unlike other OSA treatments, upper airway stimulation (UAS) therapy activates neuromuscular anatomy to increase upper airway caliber without the need for surgical removal or alteration of soft or skeletal tissue (Maurer, 2012). The system works by sensing respiration and applying a small stimulus directly to the hypoglossal nerve which is then synchronized to diaphragmatic movement. This stimulation improves airway patency by activating muscles in the tongue mimicking wakeful function. Multiple studies have shown that a reduction in the tone of the pharyngeal and lingual musculature is associated with a significant increase in airflow resistance and pharyngeal obstruction (Maurer, 2012). The Inspire system targets these muscles and increases muscle tone in a synchronized manner, opening the airway and moving obstructing tissue simultaneously. The system is composed of a stimulation lead, a sensing lead, and an implantable pulse generator (IPG), which together sense respiration patterns and deliver stimulation to the hypoglossal nerve. The article goes on to state that The Inspire UAS system is best used to treat patients with moderate to severe OSA who do not tolerate positive airway pressure treatments. Several clinical investigations of the UAS therapy suggest that it is a valid strategy for reducing OSA.

Since smoking is known to further aggravate the condition of a COPD patient (Verduri et al., 2015), it is important to use interventions for making the patient quit smoking. Moreover, there is a need to teach the patient about the ways to correctly use the specified inhaler. Many a time, the patient fails to take in the correct dosage due to the wrong use of the inhaler (Melzer et al., 2017). Thus, providing inhaler usage teaching to the patient is of prime importance. The use of self-management techniques and taking the correct drug dosage at the proper time can be greatly helpful for easing the condition of the patient and also possibly help them recover.

Ipratropium, Tiotropium bromide are anticholinergic agents widely used as second-line bronchodilator (after β2-agonists). The anticholinergic agents are effective for patients with severe airway obstruction and acute asthma exacerbations leads to cholinergic activation through viral infection, allergen exposure and air pollution. The combination of anticholinergic agent with SABA is the best treatment option for the of β-blocker induced asthma.

The body slowly metabolizes the S-Isomer and it stays in the lungs longer, which could cause paradoxical bronchospasm in the long term. The concerns regarding the potential negative side effects of the S-Isomer led to the development of levalbuterol.

When CNS developed the breathing strips their goal was to create a product that would

The main areas of concern are in the mouth and oropharynx. Previous studies with a radiotracer estimate 70-80% of the formulation is deposited in the mouth and oropharynx [6]. The main reason for deposition in the mouth and oropharynx is inertial impaction, which is proportional to the droplet’s ability to travel around a bend. This is determined by whether or not its forward motion is arrested by the change in flow direction before impaction takes place. For good lung deposition the drug particles must be between 2-5µm

The antibacterial effects of sulfanilamide were first observed in 1932, when German bacteriologist and pathologist Gerhard Domagk noted the effects of the red dye Prontosil on Streptococcus infections in mice. It was later proved by French researchers that the active agent of Prontosil was sulfanilamide, or para-aminobenzenesulfonamide, a product of the body’s metabolism of Prontosil. By the 1940s sulfanilamide was a widely used drug. During World War II white sulfanilamide powders became standard in first-aid kits for the treatment of open wounds, and sulfanilamide tablets were taken to fight intestinal infections. Though the medicine was relatively safe, allergic reactions such as skin rashes, fever, nausea, vomiting, and even mental confusion

This Bi-Directional™ technology could be utilized to any type of dispersion technologies related to liquid and powder. When delivery of drug is required, a user exhaled into the mouthpiece of device, soft palate is elevated and the nasal cavity is isolated from the rest of respiratory system. The patient exhaled force emitted the medication from device into nostril while closure of the soft palate prevented the entry of drug to the lungs. Expended nasal passage delivered medication deep into the targeted area of the nasal cavity. When medicine is delivered to the targeted sites, air following “Bi-Directional™ flow path” flowed around to the opposite side of the nasal cavity and exit through the other side of the nose rather than into the throat or lungs, as depicted in fig 6 [129, 130]. Nasal valve is a narrow opening in the nasal cavity, created a barrier for delivery of drug to brain. Neural connection to brain is located posterior to this valve. Traditional nasal devices deliver drug in or anterior to this valve. Optinose is a biopharmaceutical company, patented closed-palate Bi-Directional™ Breath Powered® DDSs. This technology used exhale device to target the drug to upper posterior part of the nasal cavity, beyond this valve [130]. Role of oxytocin has already been explored in the treatment of autism spectrum. Higher doses

It is important that clients who use inhalers are able to use them in a way that gives them their max benefits. Individuals must be able to coordinate actuation of their inhaler with their inspired breaths (Hickey, 2014). If this is a difficult task for them do to the need of coordination, spacers can be beneficial in that they don’t require timing and also decrease effects of the drug in the mouth (Chrystyn & Price, 2009). Spacers make it easier for the medication that is being inhaled to reach the lungs. This results in a decrease in the amount of medication being absorbed by the mouth and throat (How to Use Your Inhaler, 2017). It is also important to note that spacer can only be used with pressurized inhalers.

Performance wise VaporFi Pro is beautiful and light, meaning there is no need to inhale too hard. It has a strong battery that lasts approximately a day or two

In general a ventolin inhaler only cost 13.78 dollar. It is a really cheap product, people can find them from local shop such is chemical warehouse or local hospitals. It has a huge convenience development for asthma people because they just need to take a few walk to get the corresponding medication to treat the disease. Ventolin is