The most common genitourinary cancers include, renal cell carcinoma of the kidney, transitional cell carcinoma of the bladder, and adenocarcinoma of the prostate.
1- Renal cell carcinoma, is the most common cancer of the kidney, accounts for approximately 90% of all renal malignancies. About 65,000 cases of renal cell carcinoma are diagnosed each year in the U.S. Despite advances in diagnosis, especially improved imaging techniques and the incidental diagnosis of many tumors with imaging tests for unrelated complaints, about 20–30% of all patients are diagnosed with metastatic disease. In addition, another 20% of patients undergoing nephrectomy will have a relapse and develop metastatic RCC during follow-up.
Kidney cancer is among the 10 most common cancers in both men and women. Overall, the lifetime risk for developing kidney cancer is about 1 in 63 (1.6%). This risk is higher in men than in women. The American Cancer Society’s most recent estimates for kidney cancer in the United States for 2016 are:
-About 62,700 new cases (39,650 in men and 23,050 in women) will occur.
-About 14,240 people (9,240 men and 5,000 women) will die from this disease.
The rate of new kidney cancers has risen since the 1990s. Part of this rise was probably due to the use of newer imaging tests such as CT scans, which picked up some cancers that might never have been found otherwise.
Imaging studies for renal cell carcinoma should include computed tomography CT scans of the abdomen and
A kidney cancer diagnosis typically begins with a complete medical history and a physical exam. Your doctor may also recommend blood and urine tests. If your doctor suspects a problem or if you're at high risk of kidney cancer, you may also have one or more of the following tests to check your kidneys for growths or tumors:
The CDC estimates that each year, more than eight million people are diagnosed, and consequently died from cancer, and this statistic was even higher in the 1950s. During this period, little was known of cancer’s effects on the
leading cause of cancer related mortality within the community for both men and women was
In Egypt, the urinary bladder cancers accounts for 30.3% of all cancers, of which the
The leading cause of cancer death for both men and women in the United States and worldwide is lung cancer. Lung cancer is responsible for thirty percent of cancer deaths in the United States. The deaths caused by breast cancer, colon cancer and prostate cancer combined do not add up to the deaths that lung cancer causes. In 2007, 158,683 people, 88,243 men and 70,354 women died from lung cancer in the United States (Eldridge, 2012). Out of the 158,683 people that died from lung cancer in 2007, 135,000 of them died of lung cancer caused by smoking cigarettes. The overall survival rate of those with lung cancer is at about fifteen percent.
Name the cell-types that define carcinomas, sarcomas, lymphomas, and leukemia’s. Which type is most common?
Kidney cancer is a cancer that begins in the kidneys. Cancer begins when cells in the body start to become uncontrollable. Cells in almost any part of the body can get to become cancerous, and can spread to different parts of the body. Renal cell carcinoma also called renal cell disease or renal cell adenocarcinoma, is by a wide margin the most well known sort of kidney cancer. Around 9 out of 10 kidney cancers are renal cell carcinomas. Despite the fact that RCC typically develops as a solitary tumor inside a kidney, at or more tumors in one kidney or even tumors in both kidneys in the meantime. There are a few subtypes of RCC, construct for the most part in light of how the cancer cells look under a magnifying instrument. Knowing the subtype
all other cancers combined. This includes breast cancer, colon cancer and lung cancer (Skin Cancer Foundation).
detailed image of the kidneys and other organs, a kidney biopsy where a small piece of
conducted by Inci et al. [26] has showed that malignant renalthe variability in MR imaging systems and the different pulse
Patients with metastatic renal cell cancer treated with TKIs at our institution (Mount Vernon Cancer Centre) from 2005 to 2009 were identified retrospectively from the clinical database. Institutional review board waiver was obtained for this retrospective analysis. Patients were selected from the database, for the analysis, based on the inclusion and exclusion criteria explained here.
Wilms tumor also called nephroblastoma is a type of cancer that causes tumors in the cells of one or both kidneys in children. According to the American Cancer Society, Wilms tumor occur in about 9 to 10 cancers in children with 5% to 10% children having one tumor in one kidney, and about 5% of children having tumors in both kidneys. This cancer begins in the kidneys and can develop in other organs in the body, if the tumor is not caught early. There are two classifications of this type of kidney cancer that determines the outcome of the treatment for the patient. By examining the tumor under a microscope the histology can be favorable where 9 to 10 Wilms tumors have a good chance of being cured, or can be unfavorable where the cells look abnormal. The abnormal cells are quite large and distorted which is called anaplasia making it more difficult to cure (American Cancer Society, 2016).
The study presented in the article „Pretreatment differentiation of renal cell carcinoma subtypes by CT: the influence of different tumor enhancement measurement approaches“ was designed as a continuation of previously performed similar uroradiologic studies in the field of renal cell carcinoma (RCC) differentiation with minimally invasive cross-sectional imaging methods such are ultrasound, computed tomography (CT) and magnetic resonance imaging. In this study, differences in enhancement between solid forms of clear cell RCC(ccRCC) and other subtypes of RCC (papillary, chromophobe, and collecting duct RCC) measured using two distinct techniques were retrospectively assessed to determine the most accurate and simple method of assessing tumor enhancement. The results of these solid renal carcinomas enhancement measurements were expressed in the form of tumor attenuation values and tumor enhancement ratios with formulas originally defined by Herts et al.(Herts BR, Coll DM, Novick AC, et al. Enhancement characteristics of papilary renal neoplasms revealed on triphasic helical CT of the kidneys AJR Am. J. Roentgenol. 2002;178:367-372), and were then correlated with pathologic reports (tumor histologic subtype). The cutoff number for each approach to the tumor enhancement measurement was chosen in order to achieve apropriate sensitivity-specificity balance with emphasis on the specificity. To the best of our knowledge, this is the first report to examine CT-based solid renal
In the U.S. kidney disease is the 8th leading cause of death with an estimated 31 million people having chronic kidney disease. Women are more likely to have chronic kidney disease than men. Compared to whites, African Americans chance of developing this disease is 3.8 times higher, Native Americans risk is 2 times higher, and Asians it is 1.3. Diabetes