The word poliomyelitis is derived from two Greek words, polio meaning grey and myelon meaning marrow which indicates the spinal cord. The classic manifestation of paralysis is the effect of polio virus on the spine (Paul, 1971). Ancient records mention crippling diseases compatible with poliomyelitis. A weakness of the lower limbs in children that was identifiable as poliomyelitis was first described by Michael Underwood in 1789. The first outbreaks were reported in the early 19th century and in 1843 in Europe and the United States respectively. For the next century, polio epidemics were reported from developed countries in the Northern Hemisphere each summer and fall. As years passed, the severity of the epidemics and the average age of persons affected increased (Birmingham et al.,1997). This led to an increase in the number of deaths as a resulting from polio. Polio cases hit a peak in the USA in 1952, where more than 21,000 paralytic cases were reported (Paul, 1971). However, polio incidence declined rapidly following introduction of …show more content…
The virus is a member of the enterovirus sub-group, family Picornaviridae. Enteroviruses are transient inhabitants of the gastrointestinal tract, and are stable at acid pH. Picornaviruses are small, ether-insensitive viruses with an RNA genome (Musa et al., 2009). It is shed in large quantities in the throat and intestines of infected persons such that a mere gram of stool may contain several million virus particle (Saunders et al., 2011). Poliovirus exists in three serotypes (P1, P2, and P3) (Dowdle & Birmingham, 1997). There is marginal heterotypic immunity between the three serotypes such that immunity to one serotype does not produce substantial immunity to the other serotypes. The poliovirus is quickly inactivated by formaldehyde, chlorine, ultraviolet light, and heat (Paul,
Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.
Nobody has ever discovered completely how it is that polio is spread. The best evidence suggests that the virus is excreted in the stool and passed through hand to hand or hand to mouth contact by people who do not wash their hands properly or often enough. It was during the first few years of the fifties and many years before then, that health department officials
Poliomyelitis was a highly infectious disease that spread through many Americans in the early 20th century. As a matter of fact, over 3,000 Americans died of the disease each year. Families were overwhelmingly desperate for doctors to find a cure. When one suffered from polio, they generally experienced painful symptoms which included not only fatigue and muscle weakness, but even death. Therefore, when the polio vaccine was introduced by scientist Jonas Salk in 1953, it greatly contributed to Americans in numerous positive ways. Environmentally, the vaccine saved countless young American lives affected by the disease thus decreasing American mortality rates. Socially, the polio vaccine convenienced families who were either directly afflicted
Poliomyelitis (polio) is a disease that attacks the nervous tissue in the spinal cord and the brain stem resulting in paralysis (Document One). Polio is caused by the poliovirus, but it is unknown how this virus is acquired. The virus enters the digestive tract and stays in the intestines for up to eight weeks, and then attacks the lymphatic system, the blood stream and eventually travels to the brain and spine (Document Four). Once it is infected in one’s body, the disease is highly contagious and can be spread through contact of saliva, food, germs, or feces (Document Two). “The poliovirus causes most of its infections in the summer and fall. At one time, summer epidemics of polio were common and greatly feared” (Document Four). This may
Polio, something that can devastate anyone and everyone so very quickly. In 1953, you didn’t know when you could be infected with this life threatening disease.
Roosevelt became president with infantile paralysis (polio), which was diagnosed in 1921, and the public found out.9 Having the American people's president seem weakened by such a disease but push on through expectations showed that little to nothing was going to get in his way and stop him.10 Including FDR's case, close to 25% of those age 21 and older had paralytic cases by the early 1950s.11 Before the vaccine, there was a peak of about 50,000 cases of polio in 1953.12 Concern of the people was also around it's highest point due to the increasing risk of the horrid disease most feared at this time. Hopes for a solution were still going strong. Friends, family, and even strangers kept prayers for those in need. Anything that could be done was done until the vaccine was established. There were even several hundred thousand children placed in a control study and out of the 749,000, only 33 from the vaccinated group developed paralytic polio.13 In addition to this trial and other performed, and conclusion was drawn stating that the vaccine was 80-90% effective against the paralytic branch of polio.14 Chances for a new beginning were showing up all over with this vaccine, even if it only helped those who haven't been diagnosed
With the last outbreak of Polio in the US being in 1979, many today have no recollection of the terror of this disease. The disease primarily infected children, and there seemed to be no pattern to who succumbed to it. No one could feel safe. Polio as a disease presents such horrors that even those who overcome it once can be plagued by its aftereffects in later life. Before vaccines, single outbreaks could devastate entire communities. One outbreak
Polio is a deadly virus that hit america in the 1930s (Franklin Roosevelt founds...N.P.). Franklin Roosevelt founds March of Dimes Polio is also known to be a crippling disease, which affected Franklin Delano Roosevelt at the age of 39. But, on January the third he created a foundation for a cure for polio called March of Dimes(Franklin Roosevelt founds March of Dimes N.P.).10 years later he created a foundation,Warm Springs Foundation, which focus entirely on the treatment of people with polio(Franklin Roosevelt founds March of Dimes N.P.). In 1934, a business, Henry Doherty donated $25,000 to establish a series of birthday balls(Franklin Roosevelt founds March of Dimes N.P.). In the first year they raised 1 million dollars off
All three strands attack the nervous system and the digestive tract, making fecal matter and vomit infectious. Polio may also be contracted through contaminated food or water. Due to the highly infectious nature of the poliovirus, epidemics were rampant in poor communities and among young children attending school. Epidemics swept the nation during the 1930s, 20s and 10s. People lived in fear of their children contracting such a harmful illness. Schools and swimming pools were closed in order to prevent the spread of the virus (Last). Mothers were warned against breastfeeding, as the virus had the potential to be spread through breast milk
“The single biggest threat to man’s continued dominance on the planet is the virus” Nobel Prize winner Joshua Lederberg once said. Throughout history, this statement has proved to be true. In fourteenth century Europe, the Bubonic Plague killed off almost half of the European population. During the first interactions between Columbus and the natives, Smallpox eradicated entire Native tribes. And in the time of the Industrial Revolution, cholera outbreaks have left millions dead. Since their outbreaks, many of these deadly viruses have been met with cures, saving millions of lives to come. However, for almost 3,500 years, one incurable virus had been attacking humanity: the poliovirus.1P
Poliomyelitis, also commonly known as polio, is a viral infection that, at one point was virtually eradicated in the US (SOURCE). The last major epidemic of polio was in the early 1950's (SOURCE). Polio was characterized in one of three ways: nonparalytic
The infection is caused by poliovirus. The disease was not known to be contagious until 1905. Most patients are infectious anywhere between seven to ten days, however a patient is still potentially contagious if the virus is present in the throat and feces. The infection can also spread through contact through saliva, but this is less likely. Incubation period for this disease is anywhere between six and twenty days. Around one out of four people with the poliovirus will have flu like symptoms including: sore throat, fever, tiredness, nausea, headache and stomach pain. These symptoms usually last two to five days and usually go away on their own. But some people infected with the poliovirus will develop more serious symptoms that affect the brain and spinal cord. Symptoms like: paralysis, meningitis (an infection in the spinal cord and/or brain), and paresthesia (feeling of pins and needles in the legs). Paralysis can lead to permanent damage and even death. Death is possible because the virus damages the muscles that make it possible to
When hygienic conditions were poor polio attacked infants. The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the
“A 1916 Polio epidemic in the United States killed 6,000 people and paralyzed 27,000 more” (“Polio Vaccine”). This lead to the creation of the polio vaccine that has helped to prevent polio for a very long time. The IPV and OPV vaccines played a huge role in all of this. Jonas Salk, who created the IPV vaccine and Albert Sabin, who created the OPV vaccine saved millions of people all around the world from polio (Petersen, Jennifer B). The IPV and OPV polio vaccine helped eliminate polio from the United States and helped prevent polio in other parts of the world (“Polio Vaccine”).
The poliovirus is one of the most transmittable and most contagious viruses that the human population has come in contact with. The structure of the poliovirus allows it to be able to bind to motor neuron cells within a host’s body and reproduce quickly. Like all virus’s, the poliovirus