Samuel's Edema And The Lymphatic System

g. By using antigen concentration to deduce the path of infection, the body’s immune system may try to fight off the antigen invader. Therefore, a limitation may be that the results are a little skewed as some of the antigens may have been killed by the body’s defense. Also, each person is different, so the body’s response to these foreign objects would have varied.

Q. The viral infection poses a kind of stress. Why might Nicholas have such a severe reaction?

The systemic inflammatory response is the next step in the continuum and is a nonspecific inflammatory state that may be seen with an infection. Sepsis is the presence of the systemic inflammatory response syndrome (SIRS) with evidence of infection. As the bacteria invade the bloodstream, they release endotoxins that damage the endothelial cell lining and impair the vascular system, coagulation mechanism, and immune system. These endotoxins also trigger the immune and inflammatory responses, which results in the activation of macrophages and CD4 cells that release proinflammatory cytokines to create a systemic inflammatory response to the pathogen. Hospitalized patients may quickly progress from bacteremia to sepsis and finally to septic shock, even with treatment.

I had a staph infection. As it was described to me, this meant that I had an internal disease that was affecting my blood and I didn’t have enough white blood cells to attack all the red blood cells in my body. It had started in my knee and traveled up to my heart.

One defence mechanism of the human body is that when a person gets ill or is infected the person will get a fever, this is a method of notifying the person. This is a bodily defence mechanism produced by the immune system, its main purpose is to make it difficult for the virus to multiply prepare for the virus. The body’s pH level will also change to make it less optimal for the virus. The immune system’s mechanism will change depending on the body’s condition. If the body gets cut the immune system will causes inflammation, this will cause red blood cells to come to the

Which type of WBCs phagocytizes damaged tissues and pathogens and may have been active early in Ed’s infection (at the site of the bite where inflammation was occurring)?

- wounds and breaks in the skin (pathogens enter the body through mucus membranes, nose, mouth, gut, genital urinary track - catheters, or wounds like surgical incisions which can cause e.g. MRSA).

The cause of the Bubonic Plague was by a living host that transport from one animal to another animal, which is called a vector-borne illness. A Xenopsylla Cheopis, an oriental rat flea, was the vector. When the flea bites, the wound is injected by infected blood and the body’s natural response to inflammatory decreases. The bacteria travels using white blood cells to find the closes lymph node, then spreads and multiplies. Lymph nodes are important because they carry fluids, waste material and nutrients to body tissues and the bloodstream. If they swell up, they can’t filter out the bad bacteria in the body. In the first few days of catching the plague, a person experiences large swelling in the lymph nodes which causes the body immune to

The WBC and platelets are high because the Pt.’s body is trying to fight an infection.

In the lymphatic system, the lymph nodes acts as filters, catching substances harmful to the body, like toxins, bacteria, cancer cells, and viruses. The plague directly targeted this form of defense. The plague has three forms of infection, based on how the bacteria were transmitted to the individual. These forms are bubonic, septicaemic and pneumonic. The Bubonic form was the most common, especially during the 14th century; this form of the plague came directly from flea bites. With the Bubonic plague, the bacteria travel to the lymph nodes where it begins to multiply. The lymph node begins to become inflamed. The swollen lymph nodes are called “buboes”. The swollen nodes soon begin to cause sores, and if left untreated, the Bubonic plague can turn into the septicaemic form. The septicaemic form is a result of the Y. pestis entering the bloodstream. Since the bacteria are overwhelming the lymph nodes, and causing them to swell, the immune system is compromised. Individuals with the septicaemic form of the plague suffer with a high fever and eventually die of multiple organ failure. The last and most fatal form of the plague is the pneumonic plague. When infected with the pneumonic plague, the individuals develop a cough due to high levels of mucus buildup in the lungs, about 99% of those who contract this form die. Although the disease is fatal if left untreated, there is

The Black Death is the most common plague. It usually follows a bite from a flea. The bacteria pass from the skin to local lymphatics and to local lymph nodes. The infection involves lymph nodes of the groin and neck may also be effected. The bacteria of the Black Death replicate in the lymph node causing it to become enlarged and swollen and tender, they are called Buboes.

The organs that make up the lymphatic and immune system are the tonsils, spleen, thymus gland, lymph nodes, and lymphatic vessels. White blood cells (leukocytes), red blood cells (erythrocytes), plasma, and platelets (thrombocytes) make up the blood. Lymphocytes are leukocytes (white blood cells) that help the body fight off diseases. Two types of lymphocytes are B cells and T cells. Lymphocytes recognize antigens, or foreign substances/matter, in the body. Lymphocytes are a classification of agranulocytes, or cells (-cytes) without (a-) granules (granul/o) in the cytoplasm. B cells are created from stem cells, which are located in the bone marrow. B cells respond to antigens by becoming plasma cells. These plasma cells then create antibodies. Memory B cells produce a stronger response with the next exposure to the antigen. B cells fight off infection and bacteria while T cells defend against viruses and cancer cells. A hormone created by the thymus gland called thymosin changes lymphocytes into T cells. The thymus gland is active when you are a child and slowly shrinks, as you get older. T cells bind to the antigens on the cells and directly attack them. T cells secrete lymphokines that increase T cell production and directly kill cells with antigens. There are three types of T cells: cytotoxic T cells, helper T cells, and memory T cells.

Stevens – Johnson syndrome (SJS) is a severe immune response-mediated hypersensitivity reaction to particular drugs or infections that causes rashes, sloughing of the skin, and the disruption of mucous membranes. This condition may affect abdomen, back, breasts, feet, gastrointestinal system, genitals, hands, head, immune system, knees, legs, lungs, neck, nose, reproductive system, respiratory system, urinary system and eyes.

(With the onset of infection the immune system is activated and signs of infection appear.)

spleen is a place for immune function, and it kills defective or aged red blood