Statement Of Purpose ( Morla Shravan )

“Nothing is so dangerous to the progress of the human mind than to assume that our views of science are ultimate, that there are no mysteries in nature, that our triumphs are complete and that there are no new worlds to conquer.”- Humphry Davy (1778-1229), British chemist and inventor. This quote sums up my desire to pursue a degree in pharmacy. My interest is in finding ways to improve the field of pharmacy by thinking in a way that makes it possible to look at every unknown in medicines and find a way to produce an answer. I chose the profession of pharmacy for many reasons, a Doctor of Pharmacy degree is a step towards reaching my goals, and my background is a large part of me achieving my goals.

Tuberculosis has been part of human history for a long time but how long is a long time? Recent research using genetic data has allowed us to know that the tuberculosis progenitor has been on this planet for about 3 million years affecting even our earlier ancestors (Gutierrez et al, 2005). Additionally this research showed that the bacilli from tuberculosis are capable of mixing sections of their genome with other strains and giving the pathogen a composite assembly, which resulted from ancient horizontal exchanges before its clonal expansion. This quality provided tuberculosis a big advantage that even now a days allows the organism to evade, adapt and create resistance to treatments that were once successful. In order to fix current and

Organic chemistry and critical thinking are important components in my future career. I found this to be the case when I asked Ashley Geisinger, Pharmacist at Meyer Pharmacy in Waverly, Iowa, what kind of influence organic chemistry and critical thinking has in pharmacy. Ashley is also married to my cousin, so I was fortunate enough to have been around her for a few years now. Prior to graduation high school and attending Grand View, I had multiple conversations with Ashley about future careers in medicine and college plans pertaining to a future in medicine.

This paper will illustrate the transmission dynamics, life cycle, and mechanisms of drug resistance in Mycobacterium tuberculosis.

I am a highly self-motivated Nigerian young man who cherishes high academic ambitions, possesses outstanding foundational pharmacy knowledge, and is determined to work harder to make even more proud achievements. My passion in life is to contribute to the advancement of Pharmacy; the academic discipline that is inextricably connected with human life and human welfare, I have always been fascinated by this subject, bent on making my own contributions to the improvement of the quality of human life.

Furthermore, my profound interest in Science courses has also helped direct me toward the pharmacy profession. During my undergraduate years, my greatest interest presented in the courses that taught about Health Sciences. It fascinated me to understand the functions and mechanics of the body and moreover, how certain drugs can interact with some of these processes. I am anticipating to learn more in detail about the several different medications and how

The pieces of this undergraduate puzzle finally fit together. The education I attained was clearly overlapping and unfolding before my very eyes. It began to make sense how the biology course tied together with chemistry, the organic with the biochemistry. How the scientific method intricately tied all these courses together into clinical research. It is not until all the puzzle pieces come together that it all makes sense. All for the better of scientific advances in medicine. I felt as I was beginning to be part of a movement to be able to expand healthcare to underserved populations.

I aspire to become a Biochemist. I trust that university will enable me to develop and enhance existing skills and knowledge to achieve my registration. I look forward to learning and adapting new techniques at university and throughout the placement, which will help me prepare for a meaningful career as a

At age five, I wanted to become a scientist. At age nine, I wanted to be a doctor. At age twelve, I thought I wanted to major in biology. At age fifteen, I found myself completing a difficult physics problem involving Newton’s Laws and solving equations. At age sixteen, I could analyze DNA fragments and run a Tollens’ test. At age eighteen, I knew that I wanted to devote my studies to learning how body mechanisms react to varying chemicals. Suitably, I started my college career as a biochemistry major.

Tuberculosis; often referred to as the silent killer, is a highly infectious disease that is contracted annually by 9.3 million individuals globally, and causes 1.8 million deaths. It’s high mortality rate led to the formation of the American Lung Association in the United States in 1904, after it was declared the leading cause of death during the nineteenth century and early twentieth century. The origin of tuberculosis is not certain; the first documented deaths were recorded in ancient Egypt and Greece, when it was known fittingly as “consumption”, coined for of its all-consuming nature. Today, tuberculosis is more of a problem in developing countries, but is still a threat in the United States. To take preventative measures to avoid contracting this deadly disease it is important to know the causes, life-cycle, how its diagnosed, interactions with the immune system, and public health actions to reduce risk of infection.Tuberculosis is a facultative intercellular bacterial parasite caused by the bacteria Mycobacterium tuberculosis. Mycobacteria are rod shaped in appearance and is a gram-positive bacterium. One characteristic unique to Mycobacteria is the addition to an extra layer beyond the thick peptidoglycan cell wall that is composed of lipids and polysaccharides; this gives M. tuberculosis a unique envelope that makes the cell have low permeability (advantage against the immune system). M. Tuberculosis doubles it’s population every 18-24 hours, which is considered

Drug resistance has been increasing among patients infected with Mycobacterium tuberculosis. Previous miracle drugs that were used in the 1950s have now been proven useless in many cases simply because the bacteria are not susceptible to antibiotics such as isoniazid, rifampin, pyrazinamide, etc. when they are taken. This pathogen is easily transmitted through air and has the capability of attacking the respiratory system and creating fatal consequences if not treated properly. A lot of people who contribute to the antibiotic resistant statistics are those that do not take medication accordingly. Even though the bacterium may not be resistant at first, it can

My academic performance was good & this acted as a booster & made me look at future with confidence & enthusiasm. In my schooling i was given with the much required information which is needed for a better scientific approach in our life. I learned that just having interest is not sufficient & that it needs to be supplemented with hard work & determination to succeed. I scored 87% in the 10th grade. This result gave me much confidence & left me with a predilection which helped for my academics. Thereafter in my pre-university exams ( 10+2 ) i secured 75%. It was this fascination & years of hard work resulted in my selection in engineering and medicine common entrance test EAMCET. which fetched me an admission into the university college of pharmacy, kakatiya university. It is among one of the best pharmacy colleges in our region with excellent faculty & competitive environment. In my undergraduate course, I have been exposed to the subjects like pharmaceutics, biotechnology, pharmacology, physiology, microbiology, inorganic chemistry, biochemistry, physical pharmacy, medicinal chemistry, organic chemistry and I was given a strong foundation in core subjects that have provided commendable groundwork for my advanced study and honed my laboratory skills in these

I have been interested in the sciences since my childhood, and this affection gradually increases day by day.When I was a college student I became more enthusiastic about chemistry. I was ranked 246 th out of almost 25,000 candidates in the entrance examination for my undergraduate admission at the University of Chittagong (CU). As part of this interest, I didn’t hesitate to choose chemistry at the undergraduate level. Now I am in the next step of building my career. An exhilarating career in the field of chemistry always been my dream and this dream infused me to choose chemical science for higher study. The Course curriculum at Chittagong university laid a firm foundation in the area of Inorganic chemistry, Organic chemistry, physical chemistry, Analytical chemistry, Industrial chemistry, etc. It is my firm conviction that I am capable of

One-forth of this world’s people are infected with Mycobacterium tuberculosis. It is the reason of virtually millions of deaths all over the world every year. This ratio is more than the deaths caused by any other pathogen. From the start of the twentieth century, tuberculosis has become a relatively uncommon disease instead of the most common reason of deaths worldwide [1-3]. The incidence of tuberculosis has waned in the developed countries. The World Health Organization reports that more than ten million cases and two to three million deaths occur annually due to tuberculosis [5]. By another estimate, it is said that at least one billion persons are infected with M. tuberculosis worldwide [6].

Agnelo English High School, U.T. of Dadra and Nagar Haveli . I secured 82.6% in Secondary School Certificate (SSC) examination which permitted me to choose Science stream with biology as my major. With my success in passing Higher Secondary Examination with overall 72%, opened my doors to choose Pharmacy as career. My schooling made me more competitive, confident and to be proficient in various activities such as debate, elocution, sports and cultural activities. I completed my Bachelor of pharmacy from Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India. Being one of the top ranked universities, it provided me a platform to gain profound knowledge in the field of Pharmacy. Through my course of four years, I learnt different subjects namely Pharmaceutical Technology, Pharmaceutical Biotechnology, Pharmacology, Pharmacognosy, Clinical Pharmacy and Therapeutics, Industrial Pharmacy, Instrumental and Biomedical Analysis and Pharmaceutical Jurisprudence and Management. I was enthralled by the extensive lab work and scope of research. By that time, I was sure that Pharmaceutical studies suited my interests than any other course and hence I decided to dedicate my efforts for the improvement of public health through research in Pharmaceutical Sciences. To be honest, what came forth as an impulse then has hitherto been the best decisions I have ever