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Statement Of Purpose Statement For Neuroscience

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Statement of Purpose

I have elected to pursue research in the field of neuroscience because I relish the approach of logical thinking to satisfy the curiosity of knowing things about me and the world around me. Neuroscience is a fascinating area with a limitless possibility of understanding and uncovering to resolve so many unanswered and unimagined questions. Although, in recent years, a large number of breakthroughs research have been done in the area of neuroscience, still, there is a lot more to discover and untangle in this area. Such an enormous amount of research work in this area has led open to the advancement in the diagnosis and therapeutic approaches to several neurological disorders and cancer such as glioma. Therefore, I decided …show more content…

I have also achieved expertise in small animal handling, animal surgery, isolation of inguinal and axillary lymph nodes and other peripheral organs, and microdissection of various brain areas (frontal cortex, striatum, medial basal hypothalamus, and hippocampus) of the rat. Currently, I am working on a review article based on the findings from my Ph. D. work and preparing the manuscript from the last chapter of the dissertation. I hope to come out with the completed papers for publication by the end of this May …show more content…

The homeostasis of the brain depends heavily on efficient energy metabolism. A number of studies have shown the role of inflammatory mediators such as nitric oxide, NF-κB, and proinflammatory cytokines play a key role in the impairment central nervous system function, thereby leading to the development of several neuroinflammatory and neurodegenerative disorders. Although not much emphasizes has been made in understanding the role of neural-immune aspect of inflammatory mediators and leukocytes infiltration in the development of glioblastoma. Therefore, understanding the role of choroid plexus and leukocytes infiltration and its association with energy metabolism in cancer will lead us in understanding the role of neural-immune interaction in the development of glioblastoma. Dr. Ellora Sen’s research work has caught my attention with her work on neuroinflammation and metabolism in glioblastoma. I believe my previous research experience in working in the area of neuroimmunology, metabolism and cancer make me a suitable candidate for this position and I would enjoy the opportunity to work in this project

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