Statement of Purpose
I have elected to pursue research in the field of neuroscience because I relish the approach of logical thinking to satisfy the curiosity of knowing things about me and the world around me. Neuroscience is a fascinating area with a limitless possibility of understanding and uncovering to resolve so many unanswered and unimagined questions. Although, in recent years, a large number of breakthroughs research have been done in the area of neuroscience, still, there is a lot more to discover and untangle in this area. Such an enormous amount of research work in this area has led open to the advancement in the diagnosis and therapeutic approaches to several neurological disorders and cancer such as glioma. Therefore, I decided
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I have also achieved expertise in small animal handling, animal surgery, isolation of inguinal and axillary lymph nodes and other peripheral organs, and microdissection of various brain areas (frontal cortex, striatum, medial basal hypothalamus, and hippocampus) of the rat. Currently, I am working on a review article based on the findings from my Ph. D. work and preparing the manuscript from the last chapter of the dissertation. I hope to come out with the completed papers for publication by the end of this May …show more content…
The homeostasis of the brain depends heavily on efficient energy metabolism. A number of studies have shown the role of inflammatory mediators such as nitric oxide, NF-κB, and proinflammatory cytokines play a key role in the impairment central nervous system function, thereby leading to the development of several neuroinflammatory and neurodegenerative disorders. Although not much emphasizes has been made in understanding the role of neural-immune aspect of inflammatory mediators and leukocytes infiltration in the development of glioblastoma. Therefore, understanding the role of choroid plexus and leukocytes infiltration and its association with energy metabolism in cancer will lead us in understanding the role of neural-immune interaction in the development of glioblastoma. Dr. Ellora Sen’s research work has caught my attention with her work on neuroinflammation and metabolism in glioblastoma. I believe my previous research experience in working in the area of neuroimmunology, metabolism and cancer make me a suitable candidate for this position and I would enjoy the opportunity to work in this project
Neurology is one of the most unexplored fields in medicine; however, more recently there has been a spike in the amount of research being done in this specialty. This is because people are becoming more interested in neuroscience, including myself. I attended a pre-medical vocational high school, which exposed me to a greater amount of knowledge pertaining to the basics of anatomy and physiology, along with hands-on opportunities in a medical setting. It was here where I realized that I wanted to pursue a career in medicine; however, due to the fact medical field is very broad, I had no set specialty. This changed when I was exposed to the cruel manifestations of Parkinson’s Disease. During, sophomore year of high school, my grandfather passed away due to complications of Parkinson’s Disease. The way that a neurodegenerative disease was able to overtake a person in the manner that it did was shocking, and while it brought me great grief initially, it later intrigued me. I took up an interest in neuroscience and began to do my own research which culminated in various projects and applications throughout the remainder of my time in high school. These experiences have culminated in my decision to work toward a Cell Biology and
I realized that growing up with a brother who suffers from an unknown neurological issue has been influential in my decision to study neuroscience, but my inherent love for science and people were what made neuroscience my passion. After this epiphany, I made a choice to take matters into my own hands. From taking the most rigorous AP courses to taking summer chemistry classes to further understand what I may have not in previous years, I have dedicated my education to be one that will enable me to help families like my own, and people like my brother. However, my learning does not stop once I leave the classroom, but rather spreads throughout my entire life. From first-hand experiences in shadowing neurosurgeons in my community, to working alongside scientists at the Van Andel Research Institute in researching the effects of Parkinson’s Disease, I try to get my hands on as many opportunities to learn as I can find. I know that the road to becoming a contributor to the field of neuroscience will be long and hard, but what keeps me going is the dream that maybe one day, I will know how to stop Diego’s
The progress of neuroscience has been significant in the past 500 years. and with the advance of technology, there is yet a multitude of chapters left to write in the history books of neuroscience. The book The Tale of the Dueling Neurosurgeons: written by Sam Kean was an engrossing and captivating read. It gives the reader a better appreciation for the growing pains of neuroscience and provides an educational, albeit entertaining overview of the anatomy and physiology of the brain and nervous system. From the early life and discoveries of Santiago Ramón y Cajal and his fascination with Golgi’s method la razione nera, which allowed Cajal to deduct after observing
My professional and academic interest in child development and neuroscience began in earnest with a field experience at the Mrs. Chris Play & Learn during my junior year of high school. I was fortunate to work with infants to pre-K ages children. During my time, I was able to observe their interactions with other children and adults, particularly their developmental changes. This experience greatly impacted me because my life devotion became to create equality in early childhood education. My education and experience over the past decade has prepared me for a career in educational neuroscience utilizing early childhood interventions to address learning discrepancies in different socioeconomic statuses. I attended Morehouse School of Medicine
In the Summer of 2015 I had the opportunity of accomplishing my own research project. With the help of my graduate student, I led us to better understand the neural pathway
Lisa Genova has her PhD in Neuroscience. She used her background in neuroscience to gain access to the chief of neurology in hospitals as well as genetic counselors and leader’s in Alzheimer’s research
The graduate program in neuroscience offered at the University of British Columbia is a research-intensive program that trains students into knowledgeable neuroscientists. In addition to the rich research experience, this program offers a diverse selection of courses, including and not limited to, neuroanatomy, psychobiology and neuropharmacology. Students applying to this graduate program may choose to complete either a MSc or a PhD program, and depending on the program chosen, the course of study can vary from 2 to 6 years. In either program throughout his/her course of study, the student will receive guidance from a Supervisory Committee consisting of four experienced neuroscientists, one of whom is the student’s research supervisor. Upon completion of either program, the student will have obtained a solid foundation in the neurosciences with specialization “in at least one area of research” (UBC, 2015).
Growing up in a family of doctors influenced me to pursue the knowledge of health and diseases. I long for devoting myself to public health. With data explosion, I realized that data-driven science is indispensable to meet the increasing demand in medical and biological improvement. Therefore, I want to apply tools of statistics to address human health problems and become an excellent biostatistician. My goal in entering in the M.S. program at Johns Hopkins University (JHU) is to develop expertise in Biostatistics. At JHU, I am able to obtain an interdisciplinary perspective, combining approaches and knowledge derived from statistics, computing and biology. In the future, I plan to pursue Ph.D. study and one day lead my own research group. To meet these objectives, I wish to carry on advanced study at JHU.
Specially, the exposure of brain parenchyma to blood circulation and the release of danger-associated molecule signals from damaged cells that initiate epileptogenic inflammatory cascades. In chronic neuro-inflammation, astrocytes and microglial cells act in a deleterious manner contributing in sustained release of pro-inflammatory cytokines, chemokines (such as S100B, interleukins [i.e., IL-1B,IL-6], tumor necrosis factor-alpha (TNF-a), interferon-y-inducible protein-10 (IP-10)), transforming growth factor (TGF) and proteases. The sensitive reactivation process and the inducible overproduction of pro-inflammatory mediators make astrocyte a very important contributor to the neuro-inflammation in the early onset of brain
have allowed scientist to study the brain and how it functions. When finding abnormalities in the
When it comes to the human body, there is still much that we do not know about the brain. However, several recent scientific advancements are working on rectifying that; 3-D imaging, fMRI’s, making brains translucent, identifying proteins and structure, and several other discoveries or tools are working together to unlock the brain. People have long been asking questions about the brain, such as how neurons communicate and bond with each other, if they can distinguish between unhealthy and healthy brains based on differences between the two, and if it is possible to bring movement (of a sort) to the paralyzed or quadriplegic. Much of the motivation behind understanding the brain is the hope that illnesses such as Alzheimer’s, autism, and schizophrenia
The high degree of customization available for my academic path in the Wiess School of Natural Sciences appeals to me. Not only would the Neuroscience major under development and the current Neuroscience minor available allow me to study how the brain works, they also let me explore how Neuroscience applies to other disciplines by encouraging specialization in psychology or neuroengineering. In the summer, I could get the hands-on experience I value by participating in research in the Institute of Biosciences and Bioengineering, or I could participate in a field-based study abroad program while immersing myself in a different culture. The opportunities at Rice seem like the endlessly blue sky, wide and limitless, and I would love to be able to take flight.
years later, brain scientists assumed that neurons connected within one another. Glial Cells represented our thoughts and that glia were kind of like stucco and grout holding the house composed. They were well-thought-out as modest insulators for neuron communication. There are some rare kinds of glial cells, but recently scientist’s experts have begun to focus on a more precise brand of glial cell called the 'astrocyte,' as they are rich in the cortex. Technologists have also exposed that astrocytes connect to themselves in the cortex and are also gifted of sending information to neurons. Finally, astrocytes are also the mature stem
Paul Furlong, Professor of Clinical Neuroimaging at Aston University (UK), states that "it's very hard to create an animal model that even equates closely to what we're trying to achieve in the human” (HUMANE SOCIETY INTERNATIONAL, 2013). This is what we need to get through scientific research in order to replace animals by new alternative scientific methods.
From an early age, I have been fascinated by how things work. It seems, listening to family, that I was never satisfied with a simple answer that machine runs on power; but always wanted to know more. As I completed my undergraduate education in ________, I became more and more interested in pursuing an advanced degree in Biomedical Engineering. My well-rounded educational pursuits thus far have served me well, engineering complimented by a sound background in the humanities and hard sciences. I have, though, a robust passion to learn more, to hone my skills even more in a field that has simply exploded over the past decade biomedical engineering.