The Polio Years : A Long Period Of Captivity Essay

Polio an American story is a scholarly readable and informative book which covers the lives of many American eminent scientists who struggled a lot to eradicate polio. This book mainly focuses on the mid twentieth century where the people are very eager to find a vaccine to eradicate polio .This book also covers the entire topics from appearance of polio symptoms to post polio syndrome which shows the valuable thesis done by David M. Oshinsky.

Paralytic poliomyelitis, "polio", held a reign of terror over this nation for decades. But unless you were born before 1955, polio may seem to be just another ephemeral disease that has been nonexistent for years. Those born before 1955 remember having a great fear of this horrible disease which crippled thousands of once active, healthy children. This disease had no cure and no identified causes, which made it all the more terrifying. People did everything that they had done in the past to prevent the spread of disease, such as quarantining areas, but these tactics never seemed to work. Polio could not be contained. Many people did not have the money to care for a family member with polio. This was one of the

Polymyelitis, otherwise known as polio, was one of the most feared diseases of the early to mid twentieth century. This disease either killed or it paralyzed its’ victims. This affected America in such a terrible way by killing or paralyzing thousands of them within the beginning of the twentieth century alone, scaring most other Americans and putting up a red flag for most health organizations. President Roosevelt, however, conceived the idea of initiating the charity that would later

To be specific, because of the fact that polio was feared by the majority of Americans, it resulted in a widespread feeling of paranoia. According to David M. Ohinsky, someone who lived through the epidemic before the vaccine, it surprisingly got to the point where people “stopped handling paper money and refused to shake hands” (1). America as a whole feared the disease because both the cause and the cure for polio was undiscovered. Significantly, Americans “looking for anything that could beat back the horror of polio offered up more than 1.8 million children to serve as test subjects” (Wilson 1). The desperation of The United States for the vaccine, was viewed negatively to American history as shown through the immense number of children forced to serve as test subjects by their parents. Even though the parents were harsh on their children by sacrificing them, it ultimately resulted in a positive outcome. This positive outcome was the successful introduction to the poliomyelitis vaccine, which left America overjoyed. The United States sacrificed many children in order to save millions more in the future. In an interview, David M. Ohinsky, an author and history professor, remembers the exact day of the polio vaccine introduction on April 25, 1955 and claimed that “the announcement came from Ann Arbor, Mich. Church bells tolled, factory whistles blew. People ran into the streets weeping” (1). The euphoria brought about a unification within the community. Moreover, it immensely filled American families with hope who were desperate for a cure. American parents no longer had to fear that their children would catch the fatal

Poliomyelitis (polio) is a disease that attacks the nervous tissue in the spinal cord and the brain stem resulting in paralysis (Document One). Polio is caused by the poliovirus, but it is unknown how this virus is acquired. The virus enters the digestive tract and stays in the intestines for up to eight weeks, and then attacks the lymphatic system, the blood stream and eventually travels to the brain and spine (Document Four). Once it is infected in one’s body, the disease is highly contagious and can be spread through contact of saliva, food, germs, or feces (Document Two). “The poliovirus causes most of its infections in the summer and fall. At one time, summer epidemics of polio were common and greatly feared” (Document Four). This may

First and foremost, I thoroughly enjoyed Guerrini's "Polio and Primates" and found it to be both informative and engaging. I did not realize prior to the reading that the path to the polio vaccine was a rushed and flawed one. I wonder how much the misinformation spread across the scientific and non-scientific communities alike as a result of Flexner's research truly "delayed the understanding of polio's complex clinic and epidemiological features" (p. 119). The reading also left me curious as to how the trajectory of polio research would have changed if President Roosevelt had never contracted it during his presidency, since his prominence ultimately led research on the virus to become a national priority. The subsequent public pressure to develop a vaccine further rushed its development with the promise to

With a substantial amount of preventive healthcare advancements behind them, the American medical community turned its attention to the deadly polio virus plaguing America. From 1937 to 1952, known cases of Americans contracting polio skyrocketed from ten thousand to a staggering figure of roughly fifty-seven thousand cases. Of those cases within that time period, approximately one thousand five hundred deaths as a result of polio were recorded. In the year 1953, The National Foundation for Infantile Paralysis provided the scientist Dr. Jonas Salk with the tools necessary to research, and develop a working vaccine to combat the devastating polio disease. After much trial and error, Dr. Salk was finally able to create what he felt was a successful polio vaccination, and proceeded to conduct a field test. After resounding success, manufacturing instructions for the Salk vaccine were sent to a series of scientific laboratories for immediate production and administration to American children. The disaster that occurred next will forever be known through American medical history as the Cutter Incident (named so after one of the labs that administered the polio vaccine). This medical crisis sent shockwaves throughout America and the medical community, and numerous lawsuits were filed against Cutter Laboratories, resulting in fewer and fewer labs willing to accept contract work in developing vaccines.

With the last outbreak of Polio in the US being in 1979, many today have no recollection of the terror of this disease. The disease primarily infected children, and there seemed to be no pattern to who succumbed to it. No one could feel safe. Polio as a disease presents such horrors that even those who overcome it once can be plagued by its aftereffects in later life. Before vaccines, single outbreaks could devastate entire communities. One outbreak

David Oshinsky's 2005 Polio: An American Story, is a history of the fight to eradicate polio in the 20th century. Polio became one of the most, if not THE most, feared diseases of the century due to the influence and example of President Franklin Roosevelt, who was stricken with the disease as an adult in 1921. Owner of a Warm Springs, GA resort dedicated to polio rehabilitation(where he died in 1945), Roosevelt needed to raise funds to keep the resort operational. In 1934, he allowed planners to throw a nationwide series of birthday parties (over 6,000) for him to raise money for the care of polio survivors and for the upkeep of Warm Springs. The success of these parties and recognition that the key to raising money during the Great Depression

The last cases of naturally occurring paralytic polio in the United States were in 1979, when an outbreak occurred among the Amish in several Midwestern states. From

The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus.

(CDC https://www.cdc.gov/mmwr/preview/mmwrhtml/00056803.htm) As the vaccine from heaven quickly spread throughout the world in an effort to eradicate the destructive virus, children from all corners of the globe began to believe they were safe from the dangers of contracting polio. The sigh of relief from these children's parents could practically be heard from space. However, just as the polio vaccine had become trusted and strides were being made to eradicate this virus for good, a batch of vaccines produced by Cutter Labs caused a hitch in the breath of parents once more. April 1955 marked the administration of a batch of polio vaccines which, in the process of inactivating the live polio virus, had been defective. This caused those who had been administered the vaccine, primarily young children, to then become infected with Polio and be subjected to the harsh effects of the disease. The parents who had been more than willing to allow their children to be administered this vaccine felt betrayed by the doctors, scientists and government officials who mandated that their children were to be given this

Polio is an infectious disease that has killed and paralyzed many people (Birth of Jonas Salk and the death of polio in India). It has taken the lives of

Dr. Jonas Salk was an American medical researcher, physician, and virologist who developed the first safe and effective polio vaccine. Before this vaccine was created, polio vaccines usually contained live, weakened forms of the virus, but Salk developed a vaccine that contained an inactivated, dead form of polio, the first of its kind. Until the Salk vaccine was introduced on April 12, 1955, polio was considered the most frightening health problem in the United Sates. Just 3 years before the vaccine was released, almost 58,000 cases were reported, with 3,145 deaths and 21,269 paralyzed. Most of the victims were children, leaving them scarred for the rest of their lives, which, depending on how bad they were affected, wasn’t long. Because

The similarity between the poliovirus and already solved plant virus’s led to a better understanding of how the poliovirus can regenerate within a host. Although the virus was similar to other plant viruses. The poliovirus was covered with more elaborate loops that are the site of monoclonal antibody escape mutations (Hogle, Chow and 229: 1358-1365Filman, Science). Individual proteins of the virus particle are produced by proteolytic cleavages from a larger precursor, yet the amino and carboxy-termini produced by proteolysis are very distinct. By noting this, Hogle and his team were able to conclude that proteolysis was not just making a lot of proteins from one gene, it is also controlling the timing of assembly (Hogle, Chow and Filman, Science 229: 1358-1365).