SLE is an autoimmune disease that is more common in women versus men. Ninety-six percent of SLE cases are in women, whereas only four percent of SLE cases occur in men. The survival rate of systemic lupus erythematosus has improved due to many factors such as earlier diagnosis, better management of disease and prevention of organ damage. Despite these advances in care, the life expectancy of patients with SLE remains, lower than the general population. SLE may also be associated with an increased prevalence of cervical cancer and other cancers thereby shortening their life spans. Cervical cancer is caused by the human papillomavirus (HPV) and is an important cause of morbidity in women. Cervical cancer is the second most common malignancy in women worldwide and despite recent discoveries in vaccines; it remains a problem in developing third world countries. Studies have indicated that HPV infections and cervical cancers are increased in patients with systemic inflammatory diseases most importantly with systemic lupus erythematosus. This increase in HPV infections and transforming infections could be due to either SLE itself or to the immunosuppressive treatments that are given to patients with autoimmune diseases. Studies have shown that immunosuppressed women with HIV have increase chance of developing cervical cancer. Mendoza et al found that levels of B cell lymphocytes and natural killer cells were lower in SLE patients who were under immunosuppressive therapy
Let alone the cause of this horrible disease. One of the most commonly suspected reasons for systemic lupus erythemotosus (SLE) is a very low iron count. Low iron has a veriaty of effects on the body including the feeling of being cold, low blood count (anemia), and impaired immune defiecency, ect.. Thus the low iron syptom seems to add up with lupus making doctor think that low iron can have a leading from in the disease.
Systemic lupus erythematosus (SLE) also referred to lupus dates back to the middle ages and has made an explosion in the past 60 years. Even though more than 1.5 million Americans have lupus and 90% of lupus sufferers are women, between the ages of 15 to 44 (Lupus Research Institute), there is little awareness about the disease. 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it (Medical News Today). However, researchers continue on working to have a better understanding of SLE factors, pathophysiology, current treatment and new prospects for treatment.
Systematic lupus erythematosus (SLE) is a chronic, systemic, autoimmune disease. This condition causes the body to mistaken its own tissues and organs as foreign bodies and begins attacking them causing continuing inflammation and pain. (Huether & McCance, 2012) The cause of SLE still remains unknown, but it is possible that is inherited as a complex trait or caused by environmental stimuli. (S) Anyone is at risk for Lupus, but is more common among women than men and is more prevalent of African Americans and Asians. (National Library of Medicine 2010, para 2) This condition can be difficult to diagnose, as a patient must present a number of the recognizable symptoms. Depending on the location that Lupus presents itself in the body, the symptoms
Most know Systemic Lupus Erythematosus (SLE) as simply lupus. It is difficult to diagnose and treat but the symptoms can be mentally and physically devastating for any patient. Many may not realize the extent to which a person with SLE is affected on a day to day basis. It is important for healthcare professionals to understand the disease process, including the cause, signs, symptoms, and treatment of SLE. By understanding the aforementioned, healthcare professionals can assist with reporting signs and symptoms to the patient’s doctor to further reach a correct diagnosis, but to provide holistic care to the patient. SLE is a heterogeneous autoimmune disease which means the body’s immune system fallaciously attacks healthy tissues and various organs, in this case, primarily the skin , joints, kidneys, and brain of both men and women.
Lupus is a disease that can damage any part of the body, whether skin, joints, or organs inside the human body. Having lupus means something goes wrong with the immune system, which is the part of the body that fights off viruses, bacteria, and germs. Autoimmune happens and your immune system cannot tell the difference between these foreigners, nor your body’s healthy tissues and creates autoantibodies that attack and destroy healthy tissue. Autoantibodies cause inflammation, pain, and damage in various parts. Lupus is also a disease that my reappear after curing and is not contagious through sexual contact and is not like or related to cancer. Lupus can become life-threatening and should always be treated by a doctor and most people with lupus can lead a full life, “research estimates that at least 1.5 million Americans have lupus.” Anybody can get infected with lupus, any race and ethnic groups
Lupus is a chronic autoimmune disease that can happen when your body's immune system attacks Some tissues and healthy organs. It is natural that the immune system protects the body from viruses and bacteria, but in the lupus attacks the healthy tissue. this disease can called systemic lupus erythematosus or SLE. It is difficult to diagnose the disease because its signs and symptoms tend to mimic other diseases. What makes diagnosis difficult is that it can not determined from just one test but by several tests it can be determine. These tests include blood, urine and physical examination. Lupus most common in women and often of childbearing age. however, children, men and teenagers can develop this disease too. most people develop this disease between the ages of 15-44 (Anonymous, 2013). Also, Scientists believe that there are 5 million people around the world who have a form of lupus and that it spreads in African-Americans, Hispanics and Asians (Anonymous, 2016) . Lupus is like any disease it has causes, symptoms and Methods of Treatment for this disease.
Lupus also known as the systemic lupus erythematosus (SLE), is an autoimmune disease which signifies that the body’s immune system attacks the healthy tissues and organs by mistake. Lupus can affect any parts of the body including skins, joints, kidneys, blood vessels and as well as cause large inflammations in the organs that are affected by the disease. When an individual is diagnosed with Lupus, their immune system becomes hyperactive and begin to attack normal healthy tissues. The immune system makes antibodies which help fights against bacteria and viruses. Lupus cause the immune system to not able to distinguish between antigens and healthy tissues. As a result of not being able to distinguish between antigens and healthy tissues, the immune system starts to direct antibodies against healthy tissues. Lupus can be mild
Systemic Lupus Erythematosus (SLE) is an autoimmune disease. Consequently, all organs and tissues are at risk of being damaged by inflammation. The most affected organs are the kidneys, lungs, heart, and skin (Harvery and Zieve; Simanta, and Mohan). The most affected tissues are the joints, and nervous tissues. The renal system controls blood pressure and blood volume. It also removes waste products and toxins from the blood. SLE causes inflammation of the nephrons, preventing the kidney to properly maintain blood volume and properly filter waste products and toxins (Harvery and Zieve). Kidney inflammation alone will trigger complications throughout the entire body. The lungs are responsible for the gas exchange with the
SLE is idiopathic, which means that the cause of the disease is unknown. It is linked to having several factors that can effect it. For example, genetics, environmental factors, and gender and/or hormones. “The disease is not linked to a certain gene, but people with lupus often have family members with other autoimmune conditions. There may be environmental triggers like ultraviolet rays, certain medications, a virus, physical or emotional stress, and trauma. SLE affects more women than men. Women also experience worsening of symptoms during pregnancy and with their menstrual periods. Both of these observations have led some medical professionals to believe that the female hormone estrogen may play a role in causing SLE. However, more research is still needed to prove this theory” (Herndon, n.d.). Our patient’s causes are unknown of why he has Systemic Lupus. We do know through patient history a previous family member does have an autoimmune disease. Also, from his frequent sun exposure he has developed a skin rash on his extremities and face.
Also, since it affects these people in such a general way, diagnosing it is nearly impossible. “Autoimmune diseases cannot be diagnosed by looking at a person's symptoms. It cannot be tested for, either. However, medical specialists can test for the antibodies that come with diseases like SLE. With that, they can assume that it is lupus” (“Questions and Answers about Autoimmunity”). Even though those antibodies are not a sure way of telling who has SLE, that is the closest thing they can get. Until people find a real way to diagnose and cure the disease, they will have to deal with their SLE. As anyone can see, this disease can cause pain in a patient, and it is hard to live with the physical and emotional effects of this
Known as SLE, systemic lupus erythematosus is classified as an autoimmune disorder, which the immune system attacks itself , that might lead to the killing of cells. Autoimmune disorders causes the immune system to overperform and ends up attacking the body. During infancy in a person who has an autoimmune disease, “their immune system “forgets” that certain antigens in the body do belong there” (Thomas). When an autoimmune disease affects more than one organ in the body, it’s classifies as a systemic autoimmune disease. SLE “is a chronic disease that causes inflammation in connective tissues, such as cartilage and the lining of blood vessels.” (Genetics Home Reference) “SLE can potentially affect any system and organ of the body”(Thomas).
There are five forms of lupus; systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus, neonatal lupus, drug-induced lupus, and discoid lupus erythematosus. There are at least 5 million people worldwide that are living with some form of lupus, according to the Lupus Foundation of America. SLE – often called “The Cruel Mystery” – can harm your skin, joints, kidneys and brain; and is fatal in some cases. There is no cure for lupus, but treatments reduce the severity of the symptoms. Flares and remissions of lupus can happen at any time. The exact cause of all forms of lupus is unknown, but there are a few factors that may play a role. Environmental factors – such as infections, sunlight, toxic chemicals, and viruses – and one’s
SLE or Systemic Lupus Erythematosis is not easy to say, and even more difficult to diagnose and live with. The patient and medical provider’s goal is to find the most effective treatment plan for each individual patient to manage the symptoms with which they are presenting. This evolves over time through working at maintaining a balance between preventing flares and the potentially life-threatening organ damage they can cause, while maintaining quality of life and minimizing the side effects that can come from various
Lupus erythematosus is an autoimmune disease that affects the connective tissue of the body. The course of disease is variable and unpredictable, with episodes of remission and relapse. Only a small percentage of patients (10%) have long-lasting remissions. Lupus takes two forms. Systemic lupus erythematosus (SLE) is a multisystem inflammatory disease that affects any body system but primarily the musculoskeletal, cutaneous, renal, nervous, and cardiovascular systems. Discoid lupus erythematosus (DLE) is a less serious form of the disease that primarily affects the skin. DLE is characterized by skin lesions of the face, scalp, and ears. Long-standing lesions can cause scarring, hypopigmentation, and redness. Only 5% to 10% of patients with
Systemic Lupus Erythematosus (SLE) is a genetic disorder. SLE is a type III hypersensitivity or an autoimmune hypersensitivity (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). Meaning that the body is attacking itself. In SLE a large number of autoantibodies circulate through the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies are deposited into the connective tissue all over the body (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). These autoantibodies activate the complement system and cause inflammation and necrosis of the tissue that the autoantibodies are near (VanMeter, K. C., PhD, & Hubert, R. J., BS, 2014). This usually takes place in many systems in the body. In order to be diagnosed at least four body systems have to be affected.