The Uses Of Metformin

Type 2 diabetes (insulin resistant) is when not enough insulin is produced by the pancreas leaving the body unable to control sugar levels in the blood. It is believed that obesity causes the body’s cells to become resistant to insulin therefore this type of diabetes is mainly associated with a lack of physical activity, obesity and poor diet. This condition is preventable through early lifestyle changes. The person may not have symptoms prior to diagnosis and the disease develops gradually meaning that as the disease gets worse the pancreas may make less insulin. (WebMD , LLC, 2012)

The body does not produce insulin so a person who has type 1 diabetes must take insulin daily (hypoglycemia).

Answer: The combination of Insulin as well as oral hyperglycaemic drugs may be prescribed for Diabetes because they help in lowering the blood glucose levels. However the primary treatment doesn’t consist of these drugs. The primary treatment comprises of Diet control, Physical activity and Weight control. If after following the primary treatment strictly, no improvement in the blood glucose level is achieved then medication is suggested for the same. Insulin helps in maintaining the blood sugar levels. Note that insulin is not to be taken orally because the acids and digestive juices in the stomach destroy it. It has to be injected under the skin only. Taking insulin leads patient to experience Hyperglycaemic condition. The Hyperglycaemic drugs helps our body to react appropriately with the insulin so that the insulin hormone is able to help transfer glucose from blood to the cells successfully.

Gower, insulin shots and medications are hardly necessary. "The medication is needed because diabetes is a disease of carbohydrate intolerance; if the patient does not eat carbs, they do not have to use medication," she said.

Insulin is a crucial thing in a Type One Diabetics life. It is the only treatment for them. Not to confuse you, but insulin is no cure by any means. Their pancreas has stopped making insulin, so they must inject themselves with insulin several times each day in order to stay alive. They also must check their blood glucose levels at least every five hours throughout the daytime to make sure it does not go to high or low and before each meal. The only real treatment for Type Two Diabetics is eating healthy foods and exercising daily. They also must check their blood glucose levels regularly, but not near as often. Some people do take insulin for their Diabetes to help their pancreas produce a little more insulin, but it is only required if food, exercise and medicine (pills) are not working.

It is necessary to consider changing from an oral diabetes medication to insulin injections after

It also prevents the usage of fat for energy. Type 1 diabetics can’t make this hormone or create very little of it, so they need to take a regular shot of insulin to keep the blood glucose levels stable . Some diabetics use a device call an insulin pump. An insulin pump is a device that delivers insulin to the body mimicking a pancreas. Some popular pumps are; Ping, T.slim, and Omnipod.

People with Type 1 diabetes receive injections to level out their metabolisms (Anspaugh, Hamrick and Rosato 444). a. Good blood sugar control reduces the risks. 2. People with Type 2 diabetes control their glucose by keeping records of their healthy diets, daily exercises, oral medications, and weight loss. a.

Dose reductions and increased frequency of glucose monitoring may be required when SOLIQUA 100/33 is coadministered with these drugs.

Another way that type 2, or non-insulin dependent diabetes can be treated is through the use of a medication called metformin (5). Metformin has French Lilac as an active ingredient, which was used in medieval Europe in the treatment diabetics. Metformin acts primarily in the liver to decrease the hepatic glucose output by sensitizing the liver to insulin (3). It also is able to increase the amount of glucagon-like peptide (3), which is a hormone stimulates the release of insulin and suppresses appetite, in both diabetic and non-diabetic adults (6). One side effect of metformin that can greatly benefit those with type 2 diabetes is that users have a tendency to lose weight since the medication is able to fix the overabundance of insulin in the bloodstream that the desensitized insulin receptors do not receive.

Dipeptidyl peptidase-4 inhibitors is a medication which reduces blood glucose by blocking DPP-4, which reduces glucagon production and increases insulin secretion. Side effects include slowed gastric emptying. A systematic review of oral medication found that most guidelines for oral medications

Insulin is an anabolic and anticatabolic hormone made by beta cell in the pancreas. It plays major roles in diabetes mellitus treatment. Insulin treatment is usually offered as subcutaneous injections with syringes, insulin pens or an insulin pump. New technique for the delivery of insulin continue to be discovered, including oral, transdermal, and inhalation delivery.1

Patients diagnosed with diabetes have elevated HbA1C levels of 6.5% or higher. The American Diabetes Association recommends a target of < 7% for most patients3 with diabetes to be considered controlled. Type 2 Diabetes patients usually begin with monotherapy oral medication, such as Metformin along with diet and exercise to decrease blood glucose levels and HbA1C levels. Unfortunately, monotherapy is not effective in many patients and they soon add a second therapy. A sulfonylurea, such as Glyburide, is a second-line drug in the treatment of diabetes because it “enhances insulin secretion”3 unlike metformin which “increases insulin sensitivity.”3

Canagliflozin is prescribed to patients with type 2 diabetes.1 The medication along with proper diet and frequent exercise will improve glycemic control in patients with type 2 diabetes.1 Canagliflozin is in the class of sodium-glucose cotransporter 2 (SGLT2) inhibitor.1,2 This medication reduces reabsorption of filtered glucose by lowering the threshold of glucose and increasing the amount of glucose that will be excreted.2

In type II diabetes, insulin is hypoactive, and does not engage in its normal role with blood glucose regulation. This is different from type I, where insulin is not even secreted by the pancreas. When insulin is not functioning properly, blood