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Variation Of Alleles

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Genetic variation of alleles is evident through physical attributes of humans and can be attributed to the specific sequence of nucleotides in DNA. Gregor Mendel experimented with plant breeding in order to determine that the inheritance of different traits is dependent upon the differences in alleles, or genes. Two loci that can measure the genetic variation in human populations are the LCT locus and the TAS2R38 locus (Leicht & McAllister, 2017). The LCT locus is located on chromosome 2, and encodes for the enzyme lactase that breaks down lactose into its monomers to aid digestion of dairy in the small intestine (Leicht & McAllister, 2017). The two potential alleles that LCT has are C and T, which can form three potential genotypes in …show more content…

We were then using the Hardy-Weinberg Principle to calculate the observed and expected values of genotype frequencies within the class and compare the results using the Chi-Square goodness of fit test (Leicht & McAllister, 2017). Demonstrated by the Hardy-Weinberg Principle, that without any evolutionary forces, the allele and genotype frequencies of sexual populations will remain constant between generations (Sadava, 2011). The Hardy-Weinberg Equilibrium is met be a population under five specific conditions: no genetic mutation, random mating between individuals (no sexual selection), infinite population size (no genetic drift, or any chance of variation with allele frequencies), no gene flow (migration of new individuals into or out of the population), and no natural selection (all genotypes contain the same relative fitness for survival and reproduction). If any of these conditions are not met, the population is not in Hardy-Weinberg Equilibrium and evolution is occurring. The expected frequencies within a population are determined by two equations: p + q = 1 for allele frequencies, and p2 + 2pq + q2 = 1 for genotype frequencies (Sadava, 2011). After using the Hardy-Weinberg Principle, we used the Chi-Square goodness of fit test to compare the expected and observed frequencies of the LCT and TAS2R38 loci, we

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