Genetic variation of alleles is evident through physical attributes of humans and can be attributed to the specific sequence of nucleotides in DNA. Gregor Mendel experimented with plant breeding in order to determine that the inheritance of different traits is dependent upon the differences in alleles, or genes. Two loci that can measure the genetic variation in human populations are the LCT locus and the TAS2R38 locus (Leicht & McAllister, 2017). The LCT locus is located on chromosome 2, and encodes for the enzyme lactase that breaks down lactose into its monomers to aid digestion of dairy in the small intestine (Leicht & McAllister, 2017). The two potential alleles that LCT has are C and T, which can form three potential genotypes in …show more content…
We were then using the Hardy-Weinberg Principle to calculate the observed and expected values of genotype frequencies within the class and compare the results using the Chi-Square goodness of fit test (Leicht & McAllister, 2017). Demonstrated by the Hardy-Weinberg Principle, that without any evolutionary forces, the allele and genotype frequencies of sexual populations will remain constant between generations (Sadava, 2011). The Hardy-Weinberg Equilibrium is met be a population under five specific conditions: no genetic mutation, random mating between individuals (no sexual selection), infinite population size (no genetic drift, or any chance of variation with allele frequencies), no gene flow (migration of new individuals into or out of the population), and no natural selection (all genotypes contain the same relative fitness for survival and reproduction). If any of these conditions are not met, the population is not in Hardy-Weinberg Equilibrium and evolution is occurring. The expected frequencies within a population are determined by two equations: p + q = 1 for allele frequencies, and p2 + 2pq + q2 = 1 for genotype frequencies (Sadava, 2011). After using the Hardy-Weinberg Principle, we used the Chi-Square goodness of fit test to compare the expected and observed frequencies of the LCT and TAS2R38 loci, we
This equation is used to calculate the genotype frequency, so 1 = 100% of the population.
Over five trials the average allele frequency with this change in the migration rate is 0.366.
For one of the monohybrid crosses you performed in this Investigation, describe how to use the phenotype ratios to determine
The degree of freedom in this experiment was 3. The chi-square value that was calculated was 1.4481. The p-value was 0.6943.
Introduction Gregor Mendel, the father of genetics, established the basic principles of heredity by crossing different varieties of pea plants and observing the succession of traits in the resulting generations. In order to studying the trends of heredity, model organisms are crossed and observed for the resulting traits. Drosophilia melanogaster, the fruit fly, has been a useful species in the study and practice of genetics. The fruit fly is an excellent model organism due to its short generation time, large offspring numbers, simply and cheap care, easy handling in a lab setting, and large and varied stocks available with minimum cost. It was among the first organisms to be used for genetic analysis (Pierce, 2005).
Briefly explain how this change in DNA affected the allele frequency of the population. Be sure to use your data in this explanation.
“If no such variations exist, the population rapidly goes extinct because it cannot adapt to a changing environment” (O’Neil, 1998-2013). Scientists call this reproductive success. “Within a specific environment context, one genotype will be better than another genotype in survival or reproduction for certain reasons having to do with the way its particular features relate to the environment or relate to other organisms within the population” (Futuyma, 2000-2014). The theory of evolution is explicable through various kinds of scientific research.
Using the Hardy-Weinberg equation, calculate the predicted genotype frequencies for each population scenario below. Place your calculations and data in the space provided below. Once you have calculated the frequencies, answer the conclusion questions for each one. Please remember that all calculations must be shown for full credit.
One of the main reasons I chose to research this gene is because of its association with
The objective of the project is to be able to determine which alleles are carried at the TAS2R38 locus and verify if the genotype reflects the expected phenotype.
Researchers screened over 3,000 genes and selected 19 random genomic regions for their comparisons, which was much more than previously cited studies. The regions that were chosen for comparison were attached to a core SNP in the coding region of a gene. This was further qualified using only fully known genomic sequence up to 160 kb in either direction of the core SNP and having a frequency of at least 35% in all ethnic groups sampled. The choice of high-frequency SNPs was explained by known factors that affect the rate. Mainly, that they tend to be found in all populations, when LD are around rare alleles the are expected to extend further because these alleles are younger and have had less recombination, and when around common alleles they tend to be more closely associated with diseases. The researchers examined 251,310 bp and found a total of 272 high-frequency SNP’s of which they chose the 19 that they examined and analyzed for this
Table 3 shows our results generated using five genetic models to evaluate associations between the
The pairs of alternative traits examined segregated among the progeny of a particular cross, some individuals exhibiting one traits, some the other
This doesn’t directly chance the frequency of alleles within the gene pool, but the new member may have a unique combination of characteristics so superior to those of other members of the population that the new member will be much more successful in producing offspring. Furthermore, In a corn population, for example, there may be alleles for resistance to corn blight (a fungal disease) and to attack by insects. Corn plants that possess both of these characteristics will be more successful than corn plants that have only one of these qualities. They will probably produce more offspring (corn seeds) than the others, because they will survive fungal and insect attacks. Thus, there will be a change in the allele frequency for these characteristics in future generations.
The law proves that natural selection is necessary for evolution to occur ("SparkNotes: population genetics," 2014). The conditions set up by the Hardy-Weinberg Law allow for variability (the existence of different alleles) and inheritance, but they eliminate natural selection ("SparkNotes: population genetics," 2014). The fact that no evolution occurs in a population meeting these conditions proves that evolution can only occur through natural selection ("SparkNotes: population genetics," 2014). The Hardy-Weinberg Law allows us to estimate the effect of selection pressures