.HbF is the predominant hemoglobin of embrions.It has two γ-and two α-subunits(α2γ2).HbF does not bind 2,3-BPG well.What is the affinity of oxygen binding for HbF in compare with HbA?For answer: 1)Explain the function of HbA and the role of 2,3-BPG in the regulation of O2 binding. 2)Draw the oxygen-binding curves of HbA and HbF. 3)Mark the Biology significance of the difference in O2 affinity for HbA and HbF.

Human Physiology: From Cells to Systems (MindTap Course List)
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ISBN:9781285866932
Author:Lauralee Sherwood
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Chapter11: The Blood
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2.HbF is the predominant hemoglobin of embrions.It has two γ-and two α-subunits(α2γ2).HbF does not bind 2,3-BPG well.What is the affinity of oxygen binding for HbF in compare with HbA?For answer: 1)Explain the function of HbA and the role of 2,3-BPG in the regulation of O2 binding. 2)Draw the oxygen-binding curves of HbA and HbF. 3)Mark the Biology significance of the difference in O2 affinity for HbA and HbF.
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