1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 cocktail 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 count 45 47 39 47 51 39 40 42 35 38 52 52 53 54 49 49 48 51 52 51 66 64 62 61 58 57 56 59 59 60

Holt Mcdougal Larson Pre-algebra: Student Edition 2012
1st Edition
ISBN:9780547587776
Author:HOLT MCDOUGAL
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Chapter11: Data Analysis And Probability
Section: Chapter Questions
Problem 8CR
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Would someone familiar with SPSS be able to help me with sub-questions b and c please?

Question 1
In a study of the in vivo effects of cytokines on in vitro clonogenicity assays, a number of rhesus macaques
(of the same age and gender) were randomly assigned to one of three treatment groups. Bone marrow
samples were taken from the monkeys after 10 days, and the number of CD34+ cell colonies determined by
flow cytometry.
The results of the trial are contained in the file Marrow. say, where two variables are listed:
●
mmm
b)
c)
cocktail A factor, with three levels, giving the group to which the monkey was assigned:
O
1 Control group, administered a placebo;
O
2 TCC group, administered the traditional cytokine cocktail;
O
3 ACD3S group, administered a conditioned media with anti-CD3.
count Number of colonies of CD34+ cells detected in vitro.
a) Produce a box plot to show a comparison of the number of colonies detected between each group.
Comment on the appearance of the plot.
Perform an analysis of variance calculation to test the null hypothesis that the mean number of
colonies is the same in all three groups of monkeys, and comment on your results.
Perform both (i) a pairwise comparison with a Bonferonni correction and (ii) a Tukey honest
significant differences analysis to determine where the significant differences lie, and discuss the
results.
Transcribed Image Text:Question 1 In a study of the in vivo effects of cytokines on in vitro clonogenicity assays, a number of rhesus macaques (of the same age and gender) were randomly assigned to one of three treatment groups. Bone marrow samples were taken from the monkeys after 10 days, and the number of CD34+ cell colonies determined by flow cytometry. The results of the trial are contained in the file Marrow. say, where two variables are listed: ● mmm b) c) cocktail A factor, with three levels, giving the group to which the monkey was assigned: O 1 Control group, administered a placebo; O 2 TCC group, administered the traditional cytokine cocktail; O 3 ACD3S group, administered a conditioned media with anti-CD3. count Number of colonies of CD34+ cells detected in vitro. a) Produce a box plot to show a comparison of the number of colonies detected between each group. Comment on the appearance of the plot. Perform an analysis of variance calculation to test the null hypothesis that the mean number of colonies is the same in all three groups of monkeys, and comment on your results. Perform both (i) a pairwise comparison with a Bonferonni correction and (ii) a Tukey honest significant differences analysis to determine where the significant differences lie, and discuss the results.
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Transcribed Image Text:1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 cocktail 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 count 45 47 39 47 51 39 40 42 35 38 52 52 53 54 49 49 48 51 52 51 66 64 62 61 58 57 56 59 59 60 var
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