1- B cell clones undergo somatic hypermutation in which structure? Group of answer choices A) Thymic cortex B) Bone marrow C) Primary focus D) Germinal center dark zone 2- During T cell development, the surrogate alpha chain (pTalpha) is considered analogous to the surrogate light chains (lambda5 and VpreB) expressed during B cell development. Which complexes do these surrogate protein chains help form in T cell and B cells, respectively? Group of answer choices A) Mature TCR and transitional B cell BCR B) Double positive thymocyte CD4/CD8 complex and mature naive B cell IgD/IgM complex C) preTCR and preBCR D) Thymic progenitor Notch receptor and early pro-B cell IL-7 receptor
1- B cell clones undergo somatic hypermutation in which structure? Group of answer choices A) Thymic cortex B) Bone marrow C) Primary focus D) Germinal center dark zone 2- During T cell development, the surrogate alpha chain (pTalpha) is considered analogous to the surrogate light chains (lambda5 and VpreB) expressed during B cell development. Which complexes do these surrogate protein chains help form in T cell and B cells, respectively? Group of answer choices A) Mature TCR and transitional B cell BCR B) Double positive thymocyte CD4/CD8 complex and mature naive B cell IgD/IgM complex C) preTCR and preBCR D) Thymic progenitor Notch receptor and early pro-B cell IL-7 receptor
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1- B cell clones undergo somatic hypermutation in which structure?
Group of answer choices
A) Thymic cortex
B) Bone marrow
C) Primary focus
D) Germinal center dark zone
2- During T cell development, the surrogate alpha chain (pTalpha) is considered analogous to the surrogate light chains (lambda5 and VpreB) expressed during B cell development.
Which complexes do these surrogate protein chains help form in T cell and B cells, respectively?
Group of answer choices
A) Mature TCR and transitional B cell BCR
B) Double positive thymocyte CD4/CD8 complex and mature naive B cell IgD/IgM complex
C) preTCR and preBCR
D) Thymic progenitor Notch receptor and early pro-B cell IL-7 receptor
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