[1] NaH HO diphenhydramine Br [2]

Q: One step in the synthesis of the antihistamine fexofenadine (Section 23.5) involves acid-catalyzed…

A: Given Structure: Reaction of A in presence of acid-calatysed hydration of H+ Following products are…

Q: Devise a stepwise mechanism for the following reaction, a key step in the synthesis of the…

A:

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

A:

Q: Although codeine occurs in low concentration in the opium poppy, most of the codeine used in…

A: The given compound is morphine. We derive codeine from morphine by selective methylation method.

Q: The analgesic naproxen can be prepared by a stepwise reaction sequence from ester A. Using enolate…

A: The most acidic proton in compound A will be the one which is attached to the carbon adjacent to the…

Q: Which carbonyl groups in the anticancer drug Taxol will undergo nucleophilic addition, and which…

A: The nucleophilic addition is a characteristic reaction of carbonyl compounds. It is sensitive…

Q: Coumarin, a naturally occurring compound isolated from lavender, sweet clover, and tonka bean, is…

A: Acetate Ion will de-protonate the phenol to form phenoxide ion as follows,

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

A: Y has to be identified and how it is formed has to be explained

Q: Но. (A LOH B LOCH

A: 2- Naphthol aniline dye is a scarlet dye can be prepared by coupling reaction. Aniline reacts with…

Q: II. Provide what is asked in the following: A. CI + H₂N- B. Product in A reacted with LiAlH4. C.…

A: In A , amide formation .In B reduction with LiAlH4. In C , N-dialkyl benzene sulfonamide formation.

Q: HN' CH3 C A

A: The hydrolysis of ester, amide and acyl chlorides depends on the tendency of how strong the leaving…

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

A: The above reaction indicates that lone pairs of electron present on the nitrogen atom of given…

Q: One step in the synthesis of the antihistamine fexofenadine involves acid-catalyzed hydration of the…

A: Acid catalyzed hydration of alkynes- Acid catalyzed hydration of alkynes produce ketone.…

Q: Decytospolides A and Bare fungal natural products that are toxic to some cancer cells, In a…

A: Concept : 1) NaH is used as base for deprotonation.  2) Grignard reagent is used as nucleophile here…

Q: When diphenyl ether is reacted under the same conditions as in Problem 22.35, a compound is produced…

A:

Q: Identify compounds A–C in the attached reaction scheme.

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Q: Muscalure, the sex pheromone of the common housey, can be prepared by a reaction sequence that uses…

A: The formation of Muscalure follows a number of steps involving nucleophilic attack at the…

Q: Mol of 5-hydroxypentanoic acid reacts with 1 mol of SOCI2 and then with 1 mol of dimethylamine. What…

A: In a chemical reaction, two or more compounds react with each other to form product(s). Organic…

Q: Amobarbital is a sedative marketed under the trade name Amytal. Propose a synthesis of amobarbital,…

A: Structure of Amobarbital is,

Q: Rank the attached compounds in order of increasing reactivity in asubstitution reaction with −CN as…

A: Nucleophilicity is defined as the tendency to give the electrons. And, a better nucleophile can…

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO),which has been converted to a…

A:

Q: 18.65 Propose a plausible synthesis for the following trans- formation. CH3 CH3 CH3

A:

Q: OH H3O* H20 он or он „CH3 H20 CH3 он

A: The mechanism for the following reaction is-

Q: What starting materials are needed to prepare each compound by the Michael reaction?

A: Organic reactions have name reactions, they are reactions named after the scientist who discovered…

Q: Even though B contains three ester groups, a single Dieckmann product results when B is treated with…

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Q: 21.(4) Provide a mechanism for the following transformation. кон heat Br

A: ->KOH is a base which can substrate Hydrogen and give elimination reaction.

Q: Q3\ The pKa of p-cyclopropylbenzoic acid is 4.45. Is cyclopropylbenzene likely to be more reactive…

A:

Q: An unknown compound A (molecular formula C7H14O) was treated withNaBH4 in CH3OH to form compound B…

A: The nuclear magnetic resonance spectroscopy or NMR deals with the study of magnetic properties of…

Q: What steps are needed to convert benzene into p-isobutylacetophenone, a synthetic intermediate used…

A: The steps required to  convert benzene into p-isobutylacetophenone are 1) reacting benzene with 2…

Q: Draw the structure of A, an intermediate in the synthesis of the antipsychotic drug risperidone.…

A: The structure of A has to be drawn

Q: Diphenhydramine, the antihistamine in Benadryl, can be prepared by the following two-step sequence.…

A:

Q: Lexan can also be prepared by the acid-catalyzed reaction of diphenyl carbonate with bisphenol A.…

A: Protonation Attack of Nucleophilic and electrophilic center

Q: d. Aflatoxin B, hemiacetal racemizes readily in basic solution. OCH3 O: OH Aflatoxin B1 hemiacetal

A: As per the rules, only the first question can be answered. Organic reaction mechanism.

Q: What steps are needed to convert benzene into p-isobutylacetophenone, a synthetic intermediate used…

A: First we need to react the benzene with the below mentioned compound in presence of AlCl3  Than the…

Q: Which stereoisomer is obtained in the following intramolecular reaction? BrMg Br a. b. d. C. **** I,

A:

Q: Coumarin, a naturally occurring compound isolated from lavender, sweet clover, and tonka bean, is…

A: Please find below the reaction mechanism.

Q: Quinapril (trade name Accupril) is used to treat high blood pressure andcongestive heart failure.…

A: The reaction mechanism along with the products is given below.

Q: Draw the curved arrow mechanism for the following reaction: Ph- Но- НО ÓMe CH2CI2 -78 °C 1 h TMEDA…

A:

Q: Diphenhydramine, the antihistamine in Benadryl, can be prepared by the following two-step sequence.…

A: The structure of diphenhydramine has to be given.

Q: 1 Mol of 5-hydroxyheptanoic acid reacts with 1 mol of SOCI2 and then with 1 mol of dimethylamine.…

A: Carboxylic acid reacts with thionyl chloride to form an acid chloride which reacts with the amine to…

Q: β-Vetivone is isolated from vetiver, a perennial grass that yields a variety of compounds used in…

A: a.

Q: The pKa of p-cyclopropylbenzoic acid is 4.45 . Is cyclopropylbenzene likely to be more reactive or…

A:

Q: Ме Ме. 'N' Me H O:

A: Concept- In the reaction there will be first addition of I2, and then elimination of HI.

Q: Coumarin, a naturally occurring compound isolated from lavender, sweet clover, and tonka bean, is…

A: The step-wise mechanism for the formation of Coumarin from Q-hydroxybenzaldehyde is given below:…

Q: What epoxide and organometallic reagent are needed to synthesize attachedalcohol?

A: Given,

Q: Draw the structure of A, an intermediate in the synthesis of theantipsychotic drug risperidone.…

A: Risperidone is an antipysichotic drug, it is used to treat bipolar, mental disorder. This medication…

Q: 18.65 Propose a plausible synthesis for the following trans- formation. CH3 CH3 CH₂

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Q: Identify the intermediates (A–C) in the following reaction sequence, which was used to prepare…

A: Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections.…

Q: What neutral nucleophile is needed to convert dihalide A to ticlopidine, an antiplatelet drug used…

A: The characteristic reaction of alkyl halide is nucleophilic substitution reaction. The substitution…

Q: Identify the intermediates (A–C) in the following reaction sequence, which was used to prepare…

A: