1. A liquid medicine having an initial drug concentration of 1000 mg/mL undergoes zero-order kinetics with a rate constant of 100 mg/mL per day. How many days does it take for the drug to degrade by 50%?
1. A liquid medicine having an initial drug concentration of 1000 mg/mL undergoes zero-order kinetics with a rate constant of 100 mg/mL per day. How many days does it take for the drug to degrade by 50%?
Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter11: Chemical Kinetics: Rates Of Reactions
Section: Chapter Questions
Problem 41QRT
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Question
1.
A liquid medicine having an initial drug concentration of 1000 mg/mL undergoes zero-order kinetics with a rate constant of 100 mg/mL per day. How many days does it take for the drug to degrade by 50%?
2.
A drug solution with initial concentration of 100 mg/mL degrades to 90 mg/mL in 1 day and to 50 mg/mL in 5 days. If the degradation follows first-order kinetics, what is the likely value of the degradation reaction rate constant?
3.
If the rate constant in a first-order degradation reaction of a drug product is 0.462/year, what is the shelf-life of the drug product in months?
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