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- Lactated Ringer’s/5% Dextrose solution contains: 6 g/L of Sodium Chloride (NaCl MW 58.5) 3.1 g/L of Sodium Lactate (C3H5O3Na MW 112) 0.3g/L of Potassium Chloride (KCl MW 74.5) 0.2g/L of Calcium Chloride (CaCl2•2H2O MW 147) 50g/L of Dextrose (C6H12O6 MW 180) You receive an order to increase the Potassium ion concentration to 0.045 mEq/mL. How many mL of 14.9% Potassium chloride injection should be added to 1L of the above solution to increase the potassium ion concentration to 0.045 mEq/mL ____________________mL 14.9% KCl injection1. You give your home health patient an unopened 500-mL bottle of guaifenesin and tellthem to take 2 teaspoons 4 times a day as ordered. They ask you how long the bottlewill last. 2. You are shadowing a nurse during a clinical who receives an order to adjust the infusionrate of a pump so that 1.6 mg of lidocaine are being delivered per minute. Hanging is a100 mL piggyback containing 0.4 grams lidocaine, a 0.4% solution. How many mL perhour should the piggyback be set to deliver? How long will the piggyback last? 3. Phenobarbital 180 mg/m 2 /24 hours given every eight hours is ordered for a childwhose BSA (body surface area) is 0.29 m 2 . How many mg will you need if the child willbe on the medication for 10 days? 4. You are going to mix a 1:10 bleach solution with water to make 500 mL of a 1:35 bleachsolution. How much 1:10 bleach solution should you use?(I recommend using the C1V1=C2V2 formula) 5. As a home health nurse you need to help a client make…In comparing direct headspace injections with SPMEheadspace injections, later eluting peaks (by GC) arelarger in SPME. Explain why.
- Two analysts each made six determinations of the paracetamol content of the same batch of tablets. The results are shown below:Analyst Paracetamol content % (m/m)A 84.32 84.51 84.63 84.61 84.64 84.51B 84.24 84.25 84.41 84.13 84.00 84.30 How many moles of the analyte P is gravimetrically equivalent to P2O5?A) 1B) 2C) 3D) 4E) 5The rate of settling for 2.5 microgram powder in glycerin is 4.25*10^-8 How did we get this result? What is the equation?Thin‑layer chromatography (TLC) can be used as a preliminary identification method for many amphetamine‑type stimulants (ATS). Using a 0.25 mm thick silica gel stationary phase and a 98.5:1.5 methanol:concentrated ammonia mobile phase, a spot was observed to have traveled 3.52 cm when the solvent front traveled 8.81 cm. What is the retardation factor (?F)for the compound that composes this spot?
- Use the following information collected from a SIZE-EXCLUSION CHROMATOGRAPHY experiment to answer the questions below. MW Standards Molecular Weight (kDa) Elution Volume (mL) blue dextran 1000 85 myoglobin 17.2 200 TIM 53.3 178 hemoglobin 62.2 156 IgG 140 122 ATCase 307.9 94 Prepare a graph showing the linear relationship between log function of molecular weight against Ve/Vo. The R2value must be 0.9 or higher. What is the linear equation from the standards given? What is the R2value?A 60-year-old woman who weighs 75kg requires a loading dose of an antibiotic to treat an infection. A plasma concentration of 4.5 mg/L of the antibiotic needs to be achieved for optimal therapeutic effectiveness. The volume of distribution (Vd) of this antibiotic is 0.2 L/kg. The salt factor (S) is 0.6 and bioavailability fraction (F) is 1. The antibiotic is available as a 100 mg/mL infusion.Loading dose = Amount of drug in the bodyBioavailability (F) x Salt fraction (S)Amount of drug in the body = Target conc. (C) x Volume of distribution (Vd)How many millilitres of antibiotic infusion need to be administered?State your answer to 1 decimal place.unit- mlA particular extraction proceeds with a distribution coefficient of 6. The system consists of 3.5 g of compound X dissolved in 60 mL of water (solvent 1). The effectiveness of three 60-mL extractions with n-hexane (solvent 2) is compared with one 180-mL extraction with n-hexane. Questions: 1. How many grams of compound X will be recovered in -hexane in the first extraction? 2. How many grams of compound X will be recovered in water in the first extraction? 3. How many grams of compound X will be recovered in n-hexane in the third extraction? 4. How many grams of compound X will be recovered in water in the third extraction?
- 4g 5 g 2 g 100 g 49." R Lactic acid Salicylic acid Trichloroacetic acid Flexible collodion qs ad Sig: wart remover. Use as directed. (a) Flexible collodion contains 20% w/w camphor and 30% w/w castor oil. How many grams of each would be contained in 30 g of the mixture? (b) The specific gravity of castor oil is 0.955. How many milliliters of the oil is contained in 30 g of the mixture? (c) If the specific gravity of the mixture is 0.781, what are the percent w/v con- centrations of lactic acid, salicylic acid, and trichloroacetic acid in the mixture?ASSAY Calibration solutions Calibration solutions of naproxen in the range 5 – 25 μg/mL were prepared. Sample preparation 20 tablets weighing 12.3819 g were crushed to a fine powder. A portion of the powder (145.4 mg) was shaken with approximately 150 mL of acetic acid (0.05 M) for 5 min and then made up to volume in a 250 mL volumetric flask (stock solution). Approximately 50 mL of the stock solution was filtered and a 25 mL aliquot was diluted to 100 mL in a volumetric flask. 10 mL of the resulting solution was further diluted to 100 mL with acetic acid (0.05 M). Analysis The standards and sample solutions were analyzed by HPLC under the following conditions: Column: octadecylsilyl (ODS), 4.6 mmx150 mm, mobile phase: acetonitrile : 0.05 M acetic acid (85:15), flow rate: 1 ml/min, UV detection at 243 nm. Results: A calibration curve of concentration versus peak area was constructed for the standard solutions and gave the straight-line equation: y = 3555.6x + 85, r = 0.9999 The area…what weight of betazole phosphotungstate might be expected in the assay of 0.1550 g sample of betazole hydrochloride containing 98% C5H9N3.2HC? Gravimetric factor = 0.0909
