1. Answer ALL parts of this question. OH IN Ph Ph 1 Figure Q1 (a) Provide a two-step retrosynthetic analysis of the fenpiprane analogue 1 (Figure Q1). In your answer account for all synthons and synthetic equivalents, and label the two retrosynthetic arrows, indicting the type of disconnection taking place. (b) Draw the two reaction schemes with viable reagents required for the synthesis of 1. (c) Give plausible curly arrow mechanisms for both reactions in the sequence drawn in part (b) required to make 1.

1. Answer ALL parts of this question. OH IN Ph Ph 1 Figure Q1 (a) Provide a two-step retrosynthetic analysis of the fenpiprane analogue 1 (Figure Q1). In your answer account for all synthons and synthetic equivalents, and label the two retrosynthetic arrows, indicting the type of disconnection taking place. (b) Draw the two reaction schemes with viable reagents required for the synthesis of 1. (c) Give plausible curly arrow mechanisms for both reactions in the sequence drawn in part (b) required to make 1.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter20: Dienes, Conjugated Systems, And Pericyclic Reactions

Section: Chapter Questions

Problem 20.38P

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