Concordance studies of twins for a neurodegenerative disorder show MZ=46% and DZ= 15%. Further studies have shown a possible link to a geneon chromosome 9, however, there are some individuals in the study whohave the allele but do not develop the disorder (group 1), and there areother individuals who do not have the allele yet develop the disorder(group 2). Amita's older sister and maternal uncle have this disorder.Currently, Amita & her 2 younger brothers do not show symptoms. Amita'spaternal grandfather was rumored to have this disorder.1. Draw the pedigree for Amita's family and determine the mode ofinheritance if any.2. Explain how the 2 groups in the study could be possible?3. What would you tell Amita about the heritability of this disorder?

Name: Concordance studies of twins for a neurodegenerative disorder show MZ
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Description: Concordance studies of twins for a neurodegenerative disorder show MZ=46% and DZ= 15%. Further studies have shown a possible link to a geneon chromosome 9, however, there are some individuals in the study whohave the allele but do not develop the di

From the given data, it is clear that the disease is autosomal, not sex-linked. As if it was…

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1. Draw the pedigree for Amita's family and determine the mode of inheritance if any. 2. Explain how the 2 groups in the study could be possible? 3. What would you tell Amita about the heritability of this disorder?

1. Draw the pedigree for Amita's family and determine the mode of inheritance if any. 2. Explain how the 2 groups in the study could be possible? 3. What would you tell Amita about the heritability of this disorder?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter18: Genetics Of Behavior

Section: Chapter Questions

Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...

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