1. Draw the structure of the enol or enolate formed under the provided conditions, and estimate Keg for the enol(ate) formation. b) a) NaOMe NaOH Kea H Keg d) c) LDA (1.1 equiv.) K2CO3 -78 °C Keg Keg f) e) H* cat. KO'Bu Kea Keg

1. Draw the structure of the enol or enolate formed under the provided conditions, and estimate Keg for the enol(ate) formation. b) a) NaOMe NaOH Kea H Keg d) c) LDA (1.1 equiv.) K2CO3 -78 °C Keg Keg f) e) H* cat. KO'Bu Kea Keg

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter23: Addition To A Carbonyl

Section: Chapter Questions

Problem 48CTQ

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Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

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( do all plz )

1. Draw the structure of the enol or enolate formed under the provided conditions, and estimate Keg for the enol(ate)
formation.
b)
a)
NaOMe
NaOH
Kea
H
Keg
d)
c)
LDA (1.1 equiv.)
K2CO3
-78 °C
Keg
Keq
f)
e)
H* cat.
KO'Bu
Kea
Keg

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