CI OEt OEt LDA two steps (2 equiv) CI B-vetivone

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter16: Synthesis Workshop 1
Section: Chapter Questions
Problem 3CTQ
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A key step in the synthesis of β-vetivone, a major constituent of vetiver, a perennial grass found in tropical and subtropical regions of the world, involved the reaction of compound A and dihalide B with two equivalents of LDA to form C. Draw a stepwise mechanism for this reaction. β-Vetivone contains a spiro ring system—that is, two rings that share a single carbon atom.

CI
OEt
OEt
LDA
two steps
(2 equiv)
CI
B-vetivone
Transcribed Image Text:CI OEt OEt LDA two steps (2 equiv) CI B-vetivone
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