1.: Male side-blotched lizards display throat color polymorphisms; some males have orange throats, some have yellow throat stripes, and some have blue throats. The following table gives genotypes observed in a California population in 1993. Genotype Individuals 2 10 oy ob 14 yy 32 yb bb 42 Please calculate: a) The allele frequencies. b) The observed heterozygosity. Note that you have more than one type of heterozygote at this locus. c) The expected heterozygosity.
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- Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?Using the HardyWeinberg Law in Human Genetics In a given population, the frequencies of the four phenotypic classes of the ABO blood groups are found to be A = 0.33, B = 0.33, AB = 0.18, and i = 0.16. What is the frequency of the i allele?Which of the following represents an example of qualitative phenotypic variation? a. the lengths of peoples toes b. the body sizes of pigeons c. human ABO blood types d. the birth weights of humans e. the number of leaves on oak trees
- If the genotype frequencies in a population are 0.60 AA, 0.20 Aa, and 0.20 aa, and if the requirements of the HardyWeinberg principle apply, the genotype frequencies in the offspring generation will be: a. 0.60 AA, 0.20 Aa, 0.20 aa. b. 0.36 AA, 0.60 Aa, 0.04 aa. c. 0.49 AA, 0.42 Aa, 0.09 aa. d. 0.70 AA, 0.00 Aa, 0.30 aa. e. 0.64 AA, 0.32 Aa, 0.04 aa.1. The ability to taste the compound PTC is controlled by a dominant allele T, while individuals homozygous for the recessive allele (t) cannot taste PTC. In a population consisting of 500 individuals, 347 are tasters and 153 are non-PTC tasters. Calculate the frequency of the T and t alleles in this population, and frequency of the genotypes.(Please train yourself to use the Hardy-Weinberg equation.)To present your answers, follow the format in the picture below.1. In a particular bird species, the tips of the feathers are tinged with blue, white, or silver. The BB genotype calls for blue-tipped feathers. The WW genotype calls for white-tipped feathers. The BW genotype calls for an intermediate with silver-tipped feathers. A mating occurs between a blue-tipped bird and a white-tipped bird. What types of offspring would be expected? Give the genotypes and phenotypes of the possible offspring and the probability of each. 2. The bird species described in question 5 has an ornamental plumage on its head. The plumage feathers are either flexible or stiff. The allele for flexible plumage is dominant over the allele for stiff plumage. A male who is heterozygous for plumage and has silver-tipped wings mates with a female who has stiff plumage with silver-tipped wings. What types of offspring would be expected from this cross? Give the probability of each. 3. In some cats, the gene for tail length shows incomplete dominance. When a cat with a…
- 1. A man and woman are both affected with the BRCA1 gene for familial breast cancer, a disease that has 80% penetrance in all individuals who carry the allele. They are both heterozygotes for the disease-causing mutation. What is the probability that they will have a phenotypically normal child?a. 20%b. 40%c. 60%d. 50%e. 80% 2. In populations in Hardy-Weinberg equilibrium, the heterozygote frequency is maximal when the A allele equalsa 0b 0.2c 0.5 d 0.8e 1.01. Two loci found in mice are suspected to be linked. To test this hypothesis, a group of graduate students performed a test cross between mice that are true breeding for both dominant traits and mice that are true breeding for both recessive traits. Individuals from the F1 generation were crossed with individuals that express both recessive traits. The phenotypic results are shown in the table below. Use chi-square analysis to determine if the graduate students’ hypothesis is supported by the evidence. Phenotype Number of OffspringDominant 1, Recessive 2 132Dominant 1, Dominant 2 128Recessive 1, Recessive 2 118Recessive 1, Dominant 2 124 a. What are the degrees of freedom and the critical chi-square value (from the table)?b. What is the calculated chi-square value?c. Do the results support that the loci are linked or that they are independently assorted (unlinked)?1. Suppose you are studying a trait due to three genes that all additively affect the same trait. The genes are A, B, and C. Capital letters symbolize the "phenotype-adding" allele and lower case letters symbolize the "non-adding" allele. (In other words, the behavior of the genes is like those affecting wheat kernel color in the Nilsson-Ehle experiment presented in class). If AaBbCc is testcrossed to aabbcc, how many different phenotypes will be produced in the progeny?
- 3. Researchers are investigating a newly discovered condition that greatly increases the likelihood of lung damage associated with the use of e-cigarettes. They found that 2% of their study population has the condition. The researchers believe they have found a useful marker locus for assessing the presence of the condition in individuals with unknown family history. They have found that, of those individuals with the condition, 99% have the marker allele M1. Of those without the condition, 99.8% have an alternative allele M2 at the marker locus. What is the probability that an individual has the condition if they have marker allele M1 and what do you conclude about the utility of the marker locus for indirect diagnosis?1. Certain flowers are either red (dominant) or white (rr). 91% of the flowers are red. Using the equations, calculate the frequency of the R allele. First you replace R and r for p and q. Thus we know that q2 = .09, because only the homozygous recessives will be white. *changed away from percentages to work the math more easily* What is the frequency of the R allele in this population? 2. In a coastal city in Nigeria, the incidence of Sickle-Cell disease is 4% of the population. Based on this information, what is the frequency of this allele in the population of that city? 3. In a given human population, only the "A" and "B" alleles are present in the ABO system; there are no individuals with type "O" blood or with O alleles in this particular population. If 200 people have type A blood, 75 have type AB blood, and 25 have type B blood, what are the alleleic frequencies of this population (i.e., what are p and q)? 4. An allele W, for white wool, is dominant over allele w, for…1. If a set of parents both have Bb genotypes, how many different types of zygotes can they form? CHOICES: A. one. B. Two C. three.D four 2. Having black hair is represented by the following alleles: A, B, and C. Which of the following genotypes represent the alleles of having brown hair? CHOICES: A. aabbcc B. AaBbcc C. AAbbcc D. AABBCC 3. Two parents have normal vision, but their son is born colorblind. What must be the mother's genotype using XB for normal and Xb for color-blind vision? B. XBXB C. XBXb D. XbXb A. XX 4. The colorblind son grows up and marries a woman with normal vision. She does not carry the colorblind allele. Their genotypes are XbYb and XBXB,respectively. By using the Punnett square solve for the percentage of the phenotype. What is the percentage that their first child will be colorblind? CHOICES: A.0% B. 25% C. 50% D. 75% 5. Which of the following traits is NOT controlled by multiple genes? A.colorblindness C. freckles B.eye color D. hair texture