   Chapter 19, Problem 9QP

Chapter
Section
Textbook Problem

Using the Hardy–Weinberg Law in Human GeneticsSuppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?

a.

Summary Introduction

To determine: The M and N allele frequencies for 1-year olds and adults.

Introduction: The allele frequency refers to number of times an allele occurs at a specific locus within a population. It can be represented as percentage or in fraction. The allele frequency is indicative of variation at a particular locus.

Explanation

The genotype frequency is denoted by q2. In case of children, the genotype frequencies are given as :

MM= (0.25)

NN= (0.25)

So in order to find the value of M and N allele separately then under root of q is taken.

Since,

q2= (0.25),

q = (0.5)

So in case of children the allele frequency of M allele is 0...

b.

Summary Introduction

To determine : Whether the allele frequencies are in equilibrium in the population or not.

Introduction: The allele frequency refers to number of times an allele occurs at a specific locus within a population. It can be represented as percentage or in fraction. The allele frequency is indicative of variation at a particular locus.

c.

Summary Introduction

To determine: Whether the genotype frequencies are in equilibrium in the population or not.

Introduction: Genotype can be described as the genetic constitution of an individual. Genotype constitutes of the genes which underlie the inheritance amongst organisms. Genotype frequency refers to the number of times a particular genotype occurs within a given population.

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