1. The following are the TLC results from running compounds A and B using column chromatography. What is the best solvent system to elute compound A? How about for compound B? Provide the basis of your answer. O-O A B A B A B A B AB A B 3:1 4:1 6:1 81 10:1 12:1 hexanes'ethyl acetate

EBK A SMALL SCALE APPROACH TO ORGANIC L
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Chapter91: Gas Chromatography
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1. The following are the TLC results from running compounds A and B using column
chromatography. What is the best solvent system to elute compound A? How about for
compound B? Provide the basis of your answer.
A B
A B
A B
A B
A B
A B
3:1
4:1
6:1
81
10:1
12:1
hexanes ethyl acetate
24 The first six fractions were analyzed by TLC to detemine their composition.
Which fractions probably contain compound's with acceptable purity?
mixture
2
3
4
5
Transcribed Image Text:1. The following are the TLC results from running compounds A and B using column chromatography. What is the best solvent system to elute compound A? How about for compound B? Provide the basis of your answer. A B A B A B A B A B A B 3:1 4:1 6:1 81 10:1 12:1 hexanes ethyl acetate 24 The first six fractions were analyzed by TLC to detemine their composition. Which fractions probably contain compound's with acceptable purity? mixture 2 3 4 5
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