1. Which are the starting materials used to synthesize the given compound through reductive amination? a. propan-1-amine and acetone b. acetone and dimethylamine c. propanal and dimethylmine d. propan-1-amine and acetaldehyde 2. Arrange the following in increasing order of acidity. I. 2,3-Dichlorobutanoic acid II. 2,2-Dichlorobutanoic acid III. 2-Chlorobutanoic acid IV. Butanoic acid a. Il

1. Which are the starting materials used to synthesize the given compound through reductive amination? a. propan-1-amine and acetone b. acetone and dimethylamine c. propanal and dimethylmine d. propan-1-amine and acetaldehyde 2. Arrange the following in increasing order of acidity. I. 2,3-Dichlorobutanoic acid II. 2,2-Dichlorobutanoic acid III. 2-Chlorobutanoic acid IV. Butanoic acid a. Il

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter23: Amines

Section: Chapter Questions

Problem 23.32P: Suppose you have a mixture of these three compounds. Devise a chemical procedure based on their...

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Why do you wash the dichloromethane solution of your reductive amination product with sodium bicarbonate, rather than dilute aqueous HCl? a) Sodium bicarbonate is a good method of removing aldehydes from organic solvent.b) The amine product will be protonated by acid and remain in the aqueous layer as a salt.c) Sodium bicarbonate transfers the amine starting material into the aqueous layer.d) Sodium bicarbonate reacts with leftover NaBH(OAc)3 and removes it from the mixture.
Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over the synthesis of a primaryamine using an alkyl halide and ammonia?
use your knowledge of acid-base extraction to come up with a plan to separate the following compounds from each other. Your plan should include specific solvents or reagents to be used and result in 4 isolated solids in the end. p-anisidine pyrene salicylic acid: 2,3-xylenol *Here is an hint and example: p=Anisidine is an amine, xylenol is a phenol, and salicylic acid has COOH and phenol groups. Always start with identifying the functional groups and you either add acids or bases to react then after you get your layer, you extract and normally you will get precipitation at the bottom and you collect it by vacuum iteration, solate the amine by extracting with HCl. The ammonium salt will be in the aqueous layer. Neutralize it by adding base (NaOH) until the solution is basic. Collect the amine(which we expect to precipitate) by vacuum filtration.
Q1- From a-haloketone how can you prepared flowing compounds : Imidazole Oxazole Thiazole Q2: compared the acidity and basicity of Pyrazole and Imidazole with Pyrrole and Pyridine ?
Suppose you have a mixture of these three compounds. Devise a chemical procedure based on their relative acidity or basicity to separate and isolate each in pure form.
1. Arrange the test samples in order of increasing reactivity with sodium bicarbonate? Explain briefly -Ethanoic acid, Butanoic acid, Benzoic acid 2. Arrange the test samples in order of increasing solubility in water? Explain briefly. -Ethylamine, Diethylamine, Aniline 3. Arrange the test samples in order of increasing basicity? Explain briefly. -NaOH, Ethylamine, Aniline
Which or which of the statements given below is correct. I) Maleic anhydride is a carboxylic acid derivative and its reaction with water is a reduction reaction. II) Fumaric acid and maleic acid are stereoisomers of each other III) Since fumaric acid has a more stable structure than maleic acid, its boiling point is higher. A. Solo I B. I and III C. II and III D. I, II, III E. Solo III
a) Which characteristics of POME would be the basis for your remediation or treatment recommendation? Briefly explain your answer b) Suggest ONE (1) most suitable POME treatment method and briefly explain your choice.
An alternative procedure for preparing the amine of Step 3 is reductive amination of the corresponding ketone. What is reductive amination? Why might this two-step route for formation of the amine be preferred over the one-step reductive amination?
Please don't ptovide handwritten solution ....
You could extract caffeine from neutral organics by treatment with aqueous HCl (acid). Write the structure of the conjugate acid of caffeine (after treatment with HCl) and explain why it would dissolve in the aqueous layer.
Several additional amine syntheses are effectively limited to making primary amines. The reduction of azides and nitrocompounds and the Gabriel synthesis leave the carbon chain unchanged. Formation and reduction of a nitrile adds onecarbon atom. Show how these amine syntheses can be used for the following conversions. (c) 1@bromo@3@phenylheptane S 3@phenylheptan@1@amine (d) 1@bromo@3@phenylheptane S 4@phenyloctan@1@amine